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3,4-dihydroxyphenylacetic acid and Melanoma

3,4-dihydroxyphenylacetic acid has been researched along with Melanoma in 5 studies

3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"3 mM) moderately increased the tyrosinase activity of cultured human melanoma cells, while another beta-adrenoceptor agonist, terbutaline (1-3 mM) and a catechol compound, dopac (0."3.67Stimulation of tyrosinase by dihydroxy phenyl derivatives. ( Karg, E; Rorsman, H; Rosengren, E, 1989)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karg, E3
Odh, G1
Wittbjer, A1
Rosengren, E3
Rorsman, H3
Pavel, S1
Matous, B1
Duchon, J1
Ito, S1
Kato, T1
Maruta, K1
Jimbow, K1
Fujita, K1

Other Studies

5 other studies available for 3,4-dihydroxyphenylacetic acid and Melanoma

ArticleYear
Hydrogen peroxide as an inducer of elevated tyrosinase level in melanoma cells.
    The Journal of investigative dermatology, 1993, Volume: 100, Issue:2 Suppl

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amitrole; Catalase; Glucose Oxidase; Humans; Hydrogen Peroxide; Mela

1993
Simple screening test for estimation of some phenolic and indolic compounds in urine application to melanoma.
    The Journal of investigative dermatology, 1978, Volume: 70, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Dihydroxyphenylalanine; Humans; Hydroxyindoleacetic Acid; Indoles; M

1978
Hydrogen peroxide as a mediator of dopac-induced effects on melanoma cells.
    The Journal of investigative dermatology, 1991, Volume: 96, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Catalase; Cell Line; Humans; Hydrogen Peroxide; Levodopa; Melanins;

1991
Stimulation of tyrosinase by dihydroxy phenyl derivatives.
    Acta dermato-venereologica, 1989, Volume: 69, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Catechol Oxidase; Cell Line; Enzyme Activation; Humans; Isoprotereno

1989
"Total" acidic metabolites of catecholamines in urine as determined by hydrolysis with hydriodic acid and liquid chromatography: application to patients with neuroblastoma and melanoma.
    Clinical chemistry, 1985, Volume: 31, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acids; Adult; Catecholamines; Child; Child, Preschool; Chromatograph

1985