3,4-dihydroxyphenylacetic acid has been researched along with Lewy Body Disease in 4 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Lewy Body Disease: A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The most common is Parkinson's disease (PD), in which putamen dopamine content is drastically reduced." | 2.66 | The "Sick-but-not-Dead" Phenomenon Applied to Catecholamine Deficiency in Neurodegenerative Diseases. ( Goldstein, DS, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldstein, DS | 4 |
| Sharabi, Y | 2 |
| Holmes, C | 1 |
| Kopin, IJ | 1 |
3 reviews available for 3,4-dihydroxyphenylacetic acid and Lewy Body Disease
| Article | Year |
|---|---|
"Sick-but-not-dead": multiple paths to catecholamine deficiency in Lewy body diseases.
Topics: 3,4-Dihydroxyphenylacetic Acid; Catecholamines; Humans; Lewy Bodies; Lewy Body Disease; Stress, Psyc | 2020 |
The "Sick-but-not-Dead" Phenomenon Applied to Catecholamine Deficiency in Neurodegenerative Diseases.
Topics: 3,4-Dihydroxyphenylacetic Acid; Autonomic Nervous System Diseases; Dopamine; Humans; Lewy Body Disea | 2020 |
The heart of PD: Lewy body diseases as neurocardiologic disorders.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Catecholamines; Dopamine; Heart; Humans; Lewy Bodie | 2019 |
1 other study available for 3,4-dihydroxyphenylacetic acid and Lewy Body Disease
| Article | Year |
|---|---|
Intra-neuronal vesicular uptake of catecholamines is decreased in patients with Lewy body diseases.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Catecholamines; Cytosol; Desipramine; Dopamine; Female; Fluori | 2011 |