3,4-dihydroxyphenylacetic acid has been researched along with Ischemic Attack, Transient in 26 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rat striatal extracellular fluid levels of dopamine, serotonin, 3-methoxytyramine (3-MT), 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5-HIAA) were measured before, during and after transient, global cerebral ischemia in awake rats using in vivo brain microdialysis." | 3.67 | Effects of transient, global, cerebral ischemia on striatal extracellular dopamine, serotonin and their metabolites. ( Clemens, JA; Phebus, LA, 1989) |
| "In the seizure animals, neurotransmitter metabolites remained at low levels, as if the hypoxia had continued after the period of ischemia, inhibiting monoamine oxidase activity and, perhaps, neurotransmitter recapture." | 1.29 | Temporal profile of aminergic neurotransmitter release in striatal dialysates in rats with post-ischemic seizures. ( Allain, H; Bellissant, E; Bentué-Ferrer, D; Decombe, R, 1994) |
| "Propentofylline (HWA285) has been reported to protect neuronal cells through the inhibition of glutamate release during transient ischemia." | 1.29 | Propentofylline (HWA285) inhibits the release of dopamine during transient ischemia and modulates its metabolism in rat striatum. ( Kawase, T; Mitani, S; Ogino, M; Saito, R; Shimizu, K; Toya, S; Yamaguchi, N, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (19.23) | 18.7374 |
| 1990's | 18 (69.23) | 18.2507 |
| 2000's | 3 (11.54) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frölich, L | 1 |
| Dirr, A | 1 |
| Riederer, P | 2 |
| Hoyer, S | 3 |
| Bentué-Ferrer, D | 3 |
| Bellissant, E | 1 |
| Decombe, R | 2 |
| Allain, H | 3 |
| Chang, CJ | 2 |
| Ishii, H | 2 |
| Yamamoto, H | 1 |
| Yamamoto, T | 1 |
| Spatz, M | 2 |
| Van den Driessche, J | 2 |
| Läer, S | 1 |
| Block, F | 1 |
| Huether, G | 1 |
| Heim, C | 2 |
| Sontag, KH | 2 |
| Richards, DA | 1 |
| Obrenovitch, TP | 1 |
| Johonson-Mora, A | 1 |
| Islekel, S | 1 |
| Symon, L | 1 |
| Curzon, G | 1 |
| Kahn, RA | 2 |
| Weinberger, J | 2 |
| Brannan, T | 1 |
| Prikhojan, A | 1 |
| Reich, DL | 2 |
| Koorn, R | 1 |
| Brannan, TS | 1 |
| Martinez-Tica, J | 1 |
| Shimizu, K | 1 |
| Ogino, M | 1 |
| Yamaguchi, N | 1 |
| Mitani, S | 1 |
| Saito, R | 1 |
| Kawase, T | 1 |
| Toya, S | 1 |
| Stanimirovic, DB | 1 |
| Mrsulja, BB | 1 |
| Yao, H | 2 |
| Nagao, T | 2 |
| Ooboshi, H | 1 |
| Matsumoto, T | 1 |
| Hirano, M | 1 |
| Nakahara, T | 1 |
| Sadoshima, S | 2 |
| Uchimura, H | 2 |
| Fujishima, M | 2 |
| Kanthan, R | 1 |
| Shuaib, A | 1 |
| Griebel, R | 1 |
| el-Alazounni, H | 1 |
| Miyashita, H | 1 |
| Kalra, J | 1 |
| Zhang, J | 1 |
| Lan, J | 1 |
| Sieklucka, M | 1 |
| Kurz, T | 1 |
| Gerlach, M | 1 |
| Ste-Marie, L | 1 |
| Vachon, P | 1 |
| Vachon, L | 1 |
| Bémeur, C | 1 |
| Guertin, MC | 1 |
| Montgomery, J | 1 |
| Cheng, FC | 1 |
| Wang, J | 1 |
| Yang, DY | 1 |
| Wood, ER | 1 |
| Coury, A | 1 |
| Blaha, CD | 1 |
| Phillips, AG | 1 |
| Ding, A | 2 |
| Németh, G | 2 |
| Cintra, A | 1 |
| Herb, JM | 1 |
| Goldstein, M | 1 |
| Agnati, LF | 1 |
| Fuxe, K | 1 |
| Uemura, Y | 1 |
| Miller, JM | 1 |
| Matson, WR | 1 |
| Beal, MF | 1 |
| Matsui, Y | 1 |
| Kumagae, Y | 1 |
| Haba, K | 1 |
| Ogawa, N | 1 |
| Mori, A | 1 |
| Reymann, JM | 1 |
| Bagot, H | 1 |
| de Certaines, J | 1 |
| Phebus, LA | 1 |
| Clemens, JA | 1 |
| Miyazaki, M | 1 |
| Nazarali, AJ | 1 |
| Boisvert, DP | 1 |
| Bayens-Simmonds, J | 1 |
| Baker, GB | 1 |
| Globus, MY | 1 |
| Busto, R | 1 |
| Dietrich, WD | 1 |
| Martinez, E | 1 |
| Valdes, I | 1 |
| Ginsberg, MD | 1 |
| Ishitsuka, T | 1 |
| Tsutsumi, T | 1 |
26 other studies available for 3,4-dihydroxyphenylacetic acid and Ischemic Attack, Transient
| Article | Year |
|---|---|
Effects of long-term recovery from transient cerebral ischemia in rat brain: tissue levels of acetylcholine, monoamines, and their metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Biogenic Monoamines; Brain; Choline; Chromat | 1993 |
Temporal profile of aminergic neurotransmitter release in striatal dialysates in rats with post-ischemic seizures.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydroxyin | 1994 |
Effects of cerebral ischemia on regional dopamine release and D1 and D2 receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebral Cortex; Corpus Striatum; Dopamine; Female; | 1993 |
Alteration of aminergic neurotransmitter release after two consecutive transient global ischaemias: an in vivo microdialysis study in rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Hyd | 1993 |
Effect of transient reduction of cerebral blood flow in normotensive rats on striatal dopamine-release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carotid Arteries; Chromatography, High Pressure Liquid; Cor | 1993 |
Effect of global ischaemia, under simulated penumbral conditions, on brain monoamine neurochemistry and subsequent neurological and histological deficits.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cerebral Cortex; Corpus Striatum; Dopamine; Electroe | 1993 |
Nitric oxide modulates dopamine release during global temporary cerebral ischemia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arginine; Corpus Striatum; Dopamine; Homovanillic Acid; Isc | 1995 |
Effect of isoflurane and halothane on in vivo ischemia-induced dopamine release in the corpus striatum of the rat. A study using cerebral microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blood Pressure; Chloral Hydrate; Corpus Striatum; Dopamine; | 1993 |
Propentofylline (HWA285) inhibits the release of dopamine during transient ischemia and modulates its metabolism in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Ulcer Agents; Corpus Striatum; Dopamine; Homovanillic | 1993 |
Dopamine metabolism and free-radical related mitochondrial injury during transient brain ischemia in gerbils.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Dialysis; Dopamine; F | 1993 |
Ischemia-induced changes in brain monoamine metabolism in aged spontaneously hypertensive rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Brain; Corpus Striatum; Dopamin | 1993 |
Evaluation of monoaminergic neurotransmitters in the acute focal ischemic human brain model by intracerebral in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Catecholamines; Chromatography, High Pressure | 1996 |
Cerebral oligaemia episode triggers free radical formation and late cognitive deficiencies.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Carotid Stenosis; Cognition Disorders; Corpu | 2000 |
Hydroxyl radical production in the cortex and striatum in a rat model of focal cerebral ischemia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Temperature; Cerebral Cortex; Cerebrovascular Circulat | 2000 |
A dual-probe microdialysis study in simultaneously monitoring extracellular pyruvate, lactate, and biogenic amines in gerbil striata during unilateral cerebral ischemia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Corpus Striatum; Dopamine; Functional Late | 2000 |
Extracellular dopamine in the rat striatum during ischemia and reperfusion as measured by in vivo electrochemistry and in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dial | 1992 |
Age influences abnormalities in striatal dopamine metabolism during and after transient forebrain ischemia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; | 1992 |
Changes in striatal dopamine neurohistochemistry and biochemistry after incomplete transient cerebral ischemia in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopa | 1991 |
Neurochemical analysis of focal ischemia in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cysteine; Free Radicals; Glutathione; Guanosine; Hydroxyind | 1991 |
Monoamine oxidase inhibitors prevent striatal neuronal necrosis induced by transient forebrain ischemia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Clorgyline; Corpus Striatum; Dopamine; Ischemic Attack, Tra | 1991 |
The effects of sho-saiko-to-go-keishi-ka-shakuyaku-to (TJ-960) on ischemia-induced changes of brain acetylcholine and monoamine levels in gerbils.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Biogenic Monoamines; Brain; Cerebral Cortex; | 1990 |
Aminergic neurotransmitter and water content changes in rats after transient forebrain ischemia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Water; Brain Chemistry; Cerebral Cortex; Corpus Striat | 1986 |
Effects of transient, global, cerebral ischemia on striatal extracellular dopamine, serotonin and their metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Ischemia; Corpus Striatum; Dopamine; Extracellular Sp | 1989 |
Inhibition of ischemia-induced brain catecholamine alterations by clonidine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Clonidine; Gerbillinae; Homovanillic Acid; | 1989 |
Effect of ischemia on the in vivo release of striatal dopamine, glutamate, and gamma-aminobutyric acid studied by intracerebral microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebrovascular Circulation; Corpus Striatum; Denervation; | 1988 |
Massive striatal dopamine release in acute cerebral ischemia in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carotid Arteries; Cerebrovascular Circulation; Corpus Stria | 1988 |