3,4-dihydroxyphenylacetic acid has been researched along with Hypotension, Orthostatic in 5 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Hypotension, Orthostatic: A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Parkinson disease with orthostatic hypotension (PD + OH) and the parkinsonian form of multiple system atrophy (MSA-P) can be difficult to distinguish clinically." | 1.42 | Plasma biomarkers of decreased vesicular storage distinguish Parkinson disease with orthostatic hypotension from the parkinsonian form of multiple system atrophy. ( Goldstein, DS; Holmes, C; Kopin, IJ; Sharabi, Y, 2015) |
| "Patients with neurogenic orthostatic hypotension can have deficits in sympathetic neural function at any of several levels of the sympathetic neuraxis." | 1.28 | Patterns of plasma levels of catechols in neurogenic orthostatic hypotension. ( Biaggioni, I; Brown, RT; Garty, M; Goldstein, DS; Kopin, IJ; Polinsky, RJ; Robertson, D; Stull, R, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, J | 1 |
| He, C | 1 |
| Yan, QX | 1 |
| Wang, HD | 1 |
| Li, KX | 1 |
| Sun, X | 1 |
| Feng, Y | 1 |
| Zha, RR | 1 |
| Cui, CP | 1 |
| Xiong, X | 1 |
| Gao, S | 1 |
| Wang, X | 1 |
| Yin, RX | 1 |
| Qiao, GF | 1 |
| Li, BY | 1 |
| Goldstein, DS | 4 |
| Kopin, IJ | 3 |
| Sharabi, Y | 1 |
| Holmes, C | 2 |
| Whittaker, N | 1 |
| Heredia-Moya, J | 1 |
| Yamamoto, T | 1 |
| Polinsky, RJ | 2 |
| Baucom, CE | 1 |
| Garty, M | 1 |
| Robertson, D | 1 |
| Brown, RT | 1 |
| Biaggioni, I | 1 |
| Stull, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Norepinephrine Transporter Blockade as a Pathophysiological Biomarker in Neurogenic Orthostatic Hypotension[NCT01316666] | 50 participants (Actual) | Observational | 2011-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for 3,4-dihydroxyphenylacetic acid and Hypotension, Orthostatic
| Article | Year |
|---|---|
Parkinson-like early autonomic dysfunction induced by vagal application of DOPAL in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Animals; Autonomic Nervous System Diseases; Baroref | 2021 |
Plasma biomarkers of decreased vesicular storage distinguish Parkinson disease with orthostatic hypotension from the parkinsonian form of multiple system atrophy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Biomarkers; Case-Control Studies; Comorbidity; Cross-Sectional | 2015 |
Contamination of the norepinephrine prodrug droxidopa by dihydroxyphenylacetaldehyde.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aged, 80 and over; Antiparkinson Agents; Chromatography, Liqui | 2010 |
Plasma sulfoconjugated dopamine levels are normal in patients with autonomic failure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Autonomic Nervous System Diseases; Case-Control Studies; Dihydroxyph | 1996 |
Patterns of plasma levels of catechols in neurogenic orthostatic hypotension.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Catecholamines; Dihydroxyphenylalanine; Humans; Hypotension, | 1989 |