3,4-dihydroxyphenylacetic acid has been researched along with Hepatic Encephalopathy in 4 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intracerebral microdialysis was applied to monitor the neocortical extracellular levels of the aromatic amino acids phenylalanine, tyrosine, and tryptophan, the neurotransmitters dopamine (DA), noradrenaline (NA), and serotonin (5-HT), and the metabolites 3,4-dihydroxyphenylacetic acid (DOPAC) and 5-hydroxyindole-3-acetic acid (5-HIAA) in rats with various forms of experimental hepatic encephalopathy (HE)." | 3.69 | Neocortical dialysate monoamines of rats after acute, subacute, and chronic liver shunt. ( Bengtsson, F; Bergqvist, PB; Bosman, DK; Chamuleau, RA; Hjorth, S; Maas, MA; Vogels, BA, 1995) |
| "Acute hepatic encephalopathy (HE) is associated with disturbances in motor functions, but the underlying mechanisms remain obscure." | 1.30 | N-methyl-D-aspartate-evoked changes in the striatal extracellular levels of dopamine and its metabolites in vivo in rats with acute hepatic encephalopathy. ( Albrecht, J; Borkowska, HD; Hilgier, W; Oja, OS; Oja, SS; Saransaari, P, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bergqvist, PB | 1 |
| Vogels, BA | 1 |
| Bosman, DK | 1 |
| Maas, MA | 1 |
| Hjorth, S | 1 |
| Chamuleau, RA | 1 |
| Bengtsson, F | 1 |
| Hadesman, R | 1 |
| Wiesner, RH | 1 |
| Go, VL | 1 |
| Tyce, GM | 1 |
| Bergeron, M | 1 |
| Swain, MS | 1 |
| Reader, TA | 1 |
| Butterworth, RF | 1 |
| Borkowska, HD | 1 |
| Oja, SS | 1 |
| Oja, OS | 1 |
| Saransaari, P | 1 |
| Hilgier, W | 1 |
| Albrecht, J | 1 |
4 other studies available for 3,4-dihydroxyphenylacetic acid and Hepatic Encephalopathy
| Article | Year |
|---|---|
Neocortical dialysate monoamines of rats after acute, subacute, and chronic liver shunt.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acute Disease; Amino Acids; Ammonia; Animals; Biogenic Monoamines; B | 1995 |
Concentrations of 3,4-dihydroxyphenylalanine and catecholamines and metabolites in brain in an anhepatic model of hepatic encephalopathy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Catecholamines; Dihydroxyphenylalan | 1995 |
Regional alterations of dopamine and its metabolites in rat brain following portacaval anastomosis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anastomosis, Surgical; Animals; Brain; Dopamine; Hepatic Encephalopa | 1995 |
N-methyl-D-aspartate-evoked changes in the striatal extracellular levels of dopamine and its metabolites in vivo in rats with acute hepatic encephalopathy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Excitatory Amino Acid Agonists; | 1999 |