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3,4-dihydroxyphenylacetic acid and Depressive Disorder

3,4-dihydroxyphenylacetic acid has been researched along with Depressive Disorder in 21 studies

3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.

Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.

Research Excerpts

ExcerptRelevanceReference
" Chronic administration of curcumin significantly reversed levels of 3, 4-dihydroxyphenylacetic acid, noradrenaline, serotonin and 5-hydroxyindoleacetic acid in the hippocampus region of male albino rats."1.43Analysis of anti-depressant potential of curcumin against depression induced male albino wistar rats. ( Chang, XR; Li, J; Wang, L; Wu, DS, 2016)
" Previous studies have shown that chronic administration of antidepressants can reverse this behavioural deficit."1.30Behavioural and neurochemical effects of dizocilpine in the olfactory bulbectomized rat model of depression. ( Kelly, JP; Leonard, BE; Redmond, AM, 1997)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19907 (33.33)18.7374
1990's9 (42.86)18.2507
2000's3 (14.29)29.6817
2010's2 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Możdżeń, E1
Babińska, I1
Wójcikowski, J1
Antkiewicz-Michaluk, L1
Chang, XR1
Wang, L1
Li, J1
Wu, DS1
Fajardo, O1
Galeno, J1
Urbina, M1
Carreira, I1
Lima, L1
Malkesman, O1
Shayit, M1
Genud, R1
Zangen, A1
Kinor, N2
Maayan, R1
Weizman, A1
Weller, A2
Yadid, G2
Lavi-Avnon, Y1
Finberg, JP1
Gispan-Herman, I1
Stern, Y1
Schroeder, M1
Gelber, V1
Bergman, SY1
Overstreet, DH1
Linnoila, M3
Karoum, F3
Potter, WZ1
Roy, A5
Pollack, S2
Radat, F1
Berlin, I1
Spreux-Varoquaux, O1
Elatki, S1
Ferreri, M1
Puech, AJ1
Arranz, B1
Blennow, K1
Eriksson, A1
Månsson, JE1
Marcusson, J1
Redmond, AM1
Kelly, JP1
Leonard, BE1
Yoshida, K1
Higuchi, H1
Kamata, M1
Yoshimoto, M1
Shimizu, T1
Hishikawa, Y1
Maggioni, M1
Picotti, GB1
Bondiolotti, GP1
Panerai, A1
Cenacchi, T1
Nobile, P1
Brambilla, F1
Lester, D1
Pickar, D2
Doran, AR1
Ninan, P1
Paul, SM1
Koyama, T1
Lowy, MT1
Meltzer, HY1
France, RD1
Urban, BJ1
Pelton, S1
Kilts, CD1
Hong, JS1
Nemeroff, CB1
Faull, KF1
Berger, PA1
Kilkowski, J1
Anderson, PJ1
Kraemer, H1
Davis, KL1
Barchas, JD1
Kruzik, P1
Sofic, E1
Riederer, P1
Gabriel, E1
Douillet, P1

Reviews

1 review available for 3,4-dihydroxyphenylacetic acid and Depressive Disorder

ArticleYear
Recent biologic studies on suicide.
    Suicide & life-threatening behavior, 1994,Spring, Volume: 24, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Brain; Depressive Disorder; Dopamine; Follow-Up Studies; Homovanilli

1994

Trials

3 trials available for 3,4-dihydroxyphenylacetic acid and Depressive Disorder

ArticleYear
Effects of antidepressant treatments on dopamine turnover in depressed patients.
    Archives of general psychiatry, 1983, Volume: 40, Issue:9

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antidepressive Agents; Bipolar Disorder; Brompheniramine; Clo

1983
Initial monoamine oxidase-A inhibition by moclobemide does not predict the therapeutic response in patients with major depression. A double blind, randomized study.
    Psychopharmacology, 1996, Volume: 127, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antidepressive Agents; Benzamides; Biomarkers; Depressive Dis

1996
Effects of phosphatidylserine therapy in geriatric patients with depressive disorders.
    Acta psychiatrica Scandinavica, 1990, Volume: 81, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aged, 80 and over; Arousal; beta-Endorphin; beta-Lipotropin; C

1990

Other Studies

17 other studies available for 3,4-dihydroxyphenylacetic acid and Depressive Disorder

ArticleYear
1-Methyl-1,2,3,4-tetrahydroisoquinoline - The toxicological research on an exo/endogenous amine with antidepressant-like activity - In vivo, in vitro and in silico studies.
    Pharmacological reports : PR, 2019, Volume: 71, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amines; Animals; Antidepressive Agents; Brain; Depression; Depressiv

2019
Analysis of anti-depressant potential of curcumin against depression induced male albino wistar rats.
    Brain research, 2016, 07-01, Volume: 1642

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal

2016
Serotonin, serotonin 5-HT(1A) receptors and dopamine in blood peripheral lymphocytes of major depression patients.
    International immunopharmacology, 2003, Volume: 3, Issue:9

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adolescent; Adult; Chromatog

2003
Dehydroepiandrosterone in the nucleus accumbens is associated with early onset of depressive-behavior: a study in an animal model of childhood depression.
    Neuroscience, 2007, Nov-09, Volume: 149, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Age of Onset; Animals; Biogenic Monoamines; Child; Dehydroepiandrost

2007
The reward system and maternal behavior in an animal model of depression: a microdialysis study.
    Psychopharmacology, 2008, Volume: 196, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Animals, Newborn; Behavior, Animal; Body Weigh

2008
Are cerebrospinal fluid or urinary monoamine metabolite measures stronger correlates of suicidal behavior in depression?
    Neuropsychobiology, 1994, Volume: 29, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Depressive Disorder; Dopamine; Female; Homovanillic Aci

1994
Serotonergic, noradrenergic, and dopaminergic measures in suicide brains.
    Biological psychiatry, 1997, May-15, Volume: 41, Issue:10

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Adult; Brain; Depressive Disorder; Dopamine; Fe

1997
Behavioural and neurochemical effects of dizocilpine in the olfactory bulbectomized rat model of depression.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 58, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Depressive Disorder; Disease Models, Anim

1997
Single and repeated electroconvulsive shocks activate dopaminergic and 5-hydroxytryptaminergic neurotransmission in the frontal cortex of rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 1998, Volume: 22, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Depressive Disorder; Dopamine; Electric Stimulation; Electr

1998
Marked reduction in indexes of dopamine metabolism among patients with depression who attempt suicide.
    Archives of general psychiatry, 1992, Volume: 49, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Circadian Rhythm; Depressive Disorder; Dopamine; Female; Foll

1992
Concentrations of cerebrospinal fluid monoamine metabolites in suicides.
    Psychological reports, 1991, Volume: 68, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic

1991
Cerebrospinal fluid monoamine and monoamine metabolite concentrations in melancholia.
    Psychiatry research, 1985, Volume: 15, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Bipolar Disorder; Depressive Disorder; Dopamine; Female

1985
5-Hydroxytryptophan-induced cortisol response and CSF 5-HIAA in depressed patients.
    The American journal of psychiatry, 1987, Volume: 144, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Adult; Brain; Depressive Disorder; Female; Homo

1987
CSF monoamine metabolites in chronic pain.
    Pain, 1987, Volume: 31, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Back Pain; Biogenic Amines; Chronic Disease; Depressive

1987
Corrections to a 1980 article on CSF monoamine metabolites.
    The American journal of psychiatry, 1989, Volume: 146, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic

1989
Biochemical aspects of dysphoria: case study for hypothesis generation.
    Psychopathology, 1987, Volume: 20, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Affective Disorders, Psychotic; Aged; Bipolar Disorder; Brain; Depre

1987
Urinary monoamines and monoamine metabolites in subtypes of unipolar depressive disorder and normal controls.
    Psychological medicine, 1986, Volume: 16, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Catecholamines; Depressive Disorder; Dopamine; Female;

1986