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3,4-dihydroxyphenylacetic acid and Depressive Disorder, Major

3,4-dihydroxyphenylacetic acid has been researched along with Depressive Disorder, Major in 5 studies

3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.

Depressive Disorder, Major: Disorder in which five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous functioning; at least one of the symptoms is either (1) depressed mood or (2) loss of interest or pleasure. Symptoms include: depressed mood most of the day, nearly every daily; markedly diminished interest or pleasure in activities most of the day, nearly every day; significant weight loss when not dieting or weight gain; Insomnia or hypersomnia nearly every day; psychomotor agitation or retardation nearly every day; fatigue or loss of energy nearly every day; feelings of worthlessness or excessive or inappropriate guilt; diminished ability to think or concentrate, or indecisiveness, nearly every day; or recurrent thoughts of death, recurrent suicidal ideation without a specific plan, or a suicide attempt. (DSM-5)

Research Excerpts

ExcerptRelevanceReference
"In this study, plasma obtained from monozygotic twin pairs discordant for schizophrenia (n = 10) or major affective disorder (n = 3) was assayed for epinephrine, norepinephrine, dihydroxyphenylacetic acid, homovanillic acid, adrencorticotropin hormone, and cortisol."3.71Plasma hormones and catecholamine metabolites in monozygotic twins discordant for psychosis. ( Bonsall, R; Walder, DJ; Walker, EF, 2002)
"Major depressive disorder is a prevalent disease, and current pharmacotherapy is considered to be inadequate."1.38Effects of the triple reuptake inhibitor amitifadine on extracellular levels of monoamines in rat brain regions and on locomotor activity. ( Bymaster, FP; Golembiowska, K; Kowalska, M, 2012)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Wang, L1
Yang, P1
Yang, C1
Yang, D1
Wu, X1
Cao, T1
Zeng, C1
Chen, Q1
Zhang, S1
Zhu, Z1
Jiao, S1
Cai, H1
de Melo Martins, GM1
Petersen, BD1
Rübensam, G1
da Silva, JMK1
Gaspary, KV1
Wiprich, MT1
Altenhofen, S1
Bonan, CD1
Golembiowska, K1
Kowalska, M1
Bymaster, FP1
Laifenfeld, D1
Klein, E1
Ben-Shachar, D1
Walker, EF1
Bonsall, R1
Walder, DJ1

Other Studies

5 other studies available for 3,4-dihydroxyphenylacetic acid and Depressive Disorder, Major

ArticleYear
Disturbance of neurotransmitter metabolism in drug-naïve, first-episode major depressive disorder: a comparative study on adult and adolescent cohorts.
    European archives of psychiatry and clinical neuroscience, 2022, Volume: 272, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Biomarkers; Depressive Disorder, Major; Dopamine;

2022
Physical exercise prevents behavioral alterations in a reserpine-treated zebrafish: A putative depression model.
    Pharmacology, biochemistry, and behavior, 2022, Volume: 220

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Behavior, Animal; COVID-19; Depressi

2022
Effects of the triple reuptake inhibitor amitifadine on extracellular levels of monoamines in rat brain regions and on locomotor activity.
    Synapse (New York, N.Y.), 2012, Volume: 66, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Aza Co

2012
Norepinephrine alters the expression of genes involved in neuronal sprouting and differentiation: relevance for major depression and antidepressant mechanisms.
    Journal of neurochemistry, 2002, Volume: 83, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Antigens, Differentiation; Cell Differentiation; Cell Division; Cell

2002
Plasma hormones and catecholamine metabolites in monozygotic twins discordant for psychosis.
    Neuropsychiatry, neuropsychology, and behavioral neurology, 2002, Volume: 15, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adrenocorticotropic Hormone; Adult; Bipolar Disorder; Ca

2002