3,4-dihydroxyphenylacetic acid has been researched along with Dementia in 6 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a single-blind study, 12 men (mean age 63 years) with senile dementia were given nafronyl in a dosage of 100 mg eight times daily for a week, followed by 100 mg four times daily for 12 weeks." | 7.66 | Effect of nafronyl on lactate and pyruvate in the cerebrospinal fluid of patients with senile dementia. ( Berger, PA; Hollister, LE; Tinklenberg, JR; Yesavage, JA, 1982) |
| "Mean levels of the two hydrolases angiotensin-converting enzyme (ACE) and acetylcholinesterase (AChE), the dopamine metabolites dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA), and total protein concentration were examined in cerebrospinal fluid (CSF) samples from a group of patients with dementia of the Alzheimer's type, a group of comparably demented patients with Parkinson's disease, and a neurologically healthy elderly control group." | 3.67 | Cerebrospinal fluid levels of angiotensin-converting enzyme, acetylcholinesterase, and dopamine metabolites in dementia associated with Alzheimer's disease and Parkinson's disease: a correlative study. ( Direnfeld, LK; Langlais, PJ; Marquis, JK; Nixon, RA; Volicer, L; Zubenko, GS, 1986) |
| "In a single-blind study, 12 men (mean age 63 years) with senile dementia were given nafronyl in a dosage of 100 mg eight times daily for a week, followed by 100 mg four times daily for 12 weeks." | 3.66 | Effect of nafronyl on lactate and pyruvate in the cerebrospinal fluid of patients with senile dementia. ( Berger, PA; Hollister, LE; Tinklenberg, JR; Yesavage, JA, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lei, P | 1 |
| Ayton, S | 1 |
| Appukuttan, AT | 1 |
| Volitakis, I | 1 |
| Adlard, PA | 1 |
| Finkelstein, DI | 1 |
| Bush, AI | 1 |
| Yesavage, JA | 1 |
| Tinklenberg, JR | 1 |
| Hollister, LE | 1 |
| Berger, PA | 1 |
| Lindner, MD | 1 |
| Cain, CK | 1 |
| Plone, MA | 1 |
| Frydel, BR | 1 |
| Blaney, TJ | 1 |
| Emerich, DF | 1 |
| Hoane, MR | 1 |
| Zubenko, GS | 1 |
| Marquis, JK | 1 |
| Volicer, L | 1 |
| Direnfeld, LK | 1 |
| Langlais, PJ | 1 |
| Nixon, RA | 1 |
| Nakamura, S | 1 |
| Fukuda, H | 1 |
| Hara, K | 1 |
| Fukuyama, H | 1 |
| Kameyama, M | 1 |
| Bridge, TP | 1 |
| Kleinman, JE | 1 |
| Karoum, F | 1 |
| Wyatt, RJ | 1 |
6 other studies available for 3,4-dihydroxyphenylacetic acid and Dementia
| Article | Year |
|---|---|
Clioquinol rescues Parkinsonism and dementia phenotypes of the tau knockout mouse.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Clioquinol; Dementia; Disease Models, Animal; Dopami | 2015 |
Effect of nafronyl on lactate and pyruvate in the cerebrospinal fluid of patients with senile dementia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Dementia; Furans; Glucose; Homovanillic Acid; Humans; Hydroxyi | 1982 |
Incomplete nigrostriatal dopaminergic cell loss and partial reductions in striatal dopamine produce akinesia, rigidity, tremor and cognitive deficits in middle-aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Brain Mapping; Corpus Striatum; Dementia; Dopa | 1999 |
Cerebrospinal fluid levels of angiotensin-converting enzyme, acetylcholinesterase, and dopamine metabolites in dementia associated with Alzheimer's disease and Parkinson's disease: a correlative study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholinesterase; Aged; Alzheimer Disease; Cerebrospinal Fluid P | 1986 |
Biochemical aspects of Parkinson-dementia complex.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dement | 1988 |
Postmortem central catecholamines and antemortem cognitive impairment in elderly schizophrenics and controls.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Brain Chemistry; Catecholamines; Cognition; Dementia; Dopamine | 1985 |