3,4-dihydroxyphenylacetic acid has been researched along with Delayed Effects, Prenatal Exposure in 52 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Children whose mothers used cocaine during pregnancy appear to have an increased incidence of certain neurobehavioral deficits." | 3.71 | Prenatal cocaine exposure increases mesoprefrontal dopamine neuron responsivity to mild stress. ( Elsworth, JD; Morrow, BA; Roth, RH, 2001) |
| "The present study was designed to examine more fully the neurochemical and behavioral interactions that derive from continued lead and cadmium poisoning in pups, whose mothers were exposed via drinking water (300 mg/l of Pb and 10 mg/l of Cd) throughout pregnancy and lactation." | 3.71 | Pb and Cd poisoning during development alters cerebellar and striatal function in rats. ( Antonio, MT; Leret, ML; López, N, 2002) |
| " In addition, the exposure to new environmental condition elevated blood corticosterone levels and enhanced behavioral activities to a greater extent in the Dex group than in controls at 7 wk of life, suggesting that elevated glucocorticoid levels during the pregnancy mimicked prenatal mild stress, producing developmental alterations in brain monoamine metabolism, endocrine response, and behavior in adult offspring." | 3.69 | Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring. ( Kamei, K; Kitera, K; Mikuni, M; Muneoka, K; Ogawa, T; Takahashi, K; Takigawa, M, 1997) |
| " The dopaminergic turnover was measured by 3,4-dihyroxyphenilacetic acid content and 3H-Spiperone binding has been carried out to determine dopaminergic receptor alterations induced by chronic ethanol consumption during pregnancy." | 3.66 | Effects of ethanol, given during pregnancy, on the offspring dopaminergic system. ( Covelli, V; Lucchi, L; Petkov, VV; Spano, PF; Trabucchi, M, 1983) |
| "Schizophrenia is probably ascribed to perinatal neurodevelopmental deficits, and its onset might be affected by environmental factors." | 1.62 | Preventive role of regular low-intensity exercise during adolescence in schizophrenia model mice with abnormal behaviors. ( Hata, T; Hiraga, T; Koizumi, H; Mouri, A; Nabeshima, T; Oharomari, LK; Okamoto, M; Shima, T; Soya, H; Yook, JS, 2021) |
| "Idiopathic Parkinson's disease (PD) is a neurodegenerative disorder of mature and older individuals." | 1.36 | Modeling a sensitization stage and a precipitation stage for Parkinson's disease using prenatal and postnatal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration. ( Charlton, CG; King, J; Mackey, V; Muthian, G, 2010) |
| "Bisphenol A (BPA) is an endocrine-disrupting chemical, widely used in industry and dentistry." | 1.36 | Prenatal and lactational exposure to low-doses of bisphenol A alters brain monoamine concentration in adult mice. ( Fushiki, S; Itoh, K; Nakamura, K; Sugimoto, T; Yoshimoto, K, 2010) |
| " Acute or chronic administration of methamphetamine elevates the levels of the extracellular monoamine neurotransmitters, such as dopamine." | 1.35 | Prenatal methamphetamine exposure affects the mesolimbic dopaminergic system and behavior in adult offspring. ( Bubenikova-Valesova, V; Hruba, L; Janovsky, M; Kacer, P; Rambousek, L; Schutova, B; Slamberova, R; Syslova, K, 2009) |
| "Styrene was evaluated to determine its neurochemical effects in the offspring of rats exposed during the gestation period." | 1.30 | Effects of prenatal exposure to styrene on neurochemical levels in rat brain. ( Ikeda, T; Katakura, Y; Kishi, R; Miyake, H, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (13.46) | 18.7374 |
| 1990's | 17 (32.69) | 18.2507 |
| 2000's | 18 (34.62) | 29.6817 |
| 2010's | 9 (17.31) | 24.3611 |
| 2020's | 1 (1.92) | 2.80 |
| Authors | Studies |
|---|---|
| Koizumi, H | 1 |
| Hiraga, T | 1 |
| Oharomari, LK | 1 |
| Hata, T | 1 |
| Shima, T | 1 |
| Yook, JS | 1 |
| Okamoto, M | 1 |
| Mouri, A | 1 |
| Nabeshima, T | 1 |
| Soya, H | 1 |
| Dutra-Tavares, AC | 1 |
| Silva, JO | 1 |
| Nunes-Freitas, AL | 1 |
| Guimarães, VMS | 1 |
| Araújo, UC | 1 |
| Conceição, EPS | 1 |
| Moura, EG | 1 |
| Lisboa, PC | 1 |
| Filgueiras, CC | 1 |
| Manhães, AC | 1 |
| Abreu-Villaça, Y | 1 |
| Ribeiro-Carvalho, A | 1 |
| Huang, Y | 1 |
| Chen, S | 1 |
| Xu, H | 1 |
| Yu, X | 1 |
| Lai, H | 1 |
| Ho, G | 1 |
| Huang, Q | 1 |
| Shi, X | 1 |
| Rose, KM | 1 |
| Parmar, MS | 1 |
| Cavanaugh, JE | 1 |
| Walters, JL | 1 |
| Lansdell, TA | 1 |
| Lookingland, KJ | 1 |
| Baker, LE | 1 |
| Ratajczak, P | 1 |
| Kus, K | 1 |
| Gołembiowska, K | 1 |
| Noworyta-Sokołowska, K | 1 |
| Woźniak, A | 1 |
| Zaprutko, T | 1 |
| Nowakowska, E | 1 |
| Winter, C | 1 |
| Djodari-Irani, A | 1 |
| Sohr, R | 1 |
| Morgenstern, R | 1 |
| Feldon, J | 1 |
| Juckel, G | 1 |
| Meyer, U | 1 |
| Yokota, S | 1 |
| Mizuo, K | 1 |
| Moriya, N | 1 |
| Oshio, S | 1 |
| Sugawara, I | 1 |
| Takeda, K | 1 |
| Ling, Z | 1 |
| Zhu, Y | 1 |
| Tong, CW | 1 |
| Snyder, JA | 1 |
| Lipton, JW | 1 |
| Carvey, PM | 1 |
| Malanga, CJ | 1 |
| Ren, JQ | 1 |
| Guerriero, RM | 1 |
| Kosofsky, BE | 1 |
| Bubenikova-Valesova, V | 1 |
| Kacer, P | 1 |
| Syslova, K | 1 |
| Rambousek, L | 1 |
| Janovsky, M | 1 |
| Schutova, B | 1 |
| Hruba, L | 1 |
| Slamberova, R | 1 |
| Muthian, G | 1 |
| Mackey, V | 1 |
| King, J | 1 |
| Charlton, CG | 1 |
| Nakamura, K | 1 |
| Itoh, K | 1 |
| Yoshimoto, K | 1 |
| Sugimoto, T | 1 |
| Fushiki, S | 1 |
| Matsuda, S | 1 |
| Matsuzawa, D | 1 |
| Ishii, D | 1 |
| Tomizawa, H | 1 |
| Sutoh, C | 1 |
| Nakazawa, K | 1 |
| Amano, K | 1 |
| Sajiki, J | 1 |
| Shimizu, E | 1 |
| Phillips, PE | 1 |
| Johns, JM | 1 |
| Lubin, DA | 1 |
| Budygin, EA | 2 |
| Gainetdinov, RR | 2 |
| Lieberman, JA | 1 |
| Wightman, RM | 1 |
| Galineau, L | 1 |
| Belzung, C | 1 |
| Kodas, E | 1 |
| Bodard, S | 1 |
| Guilloteau, D | 1 |
| Chalon, S | 1 |
| McArthur, S | 1 |
| McHale, E | 1 |
| Dalley, JW | 1 |
| Buckingham, JC | 1 |
| Gillies, GE | 1 |
| Aldridge, JE | 1 |
| Meyer, A | 1 |
| Seidler, FJ | 2 |
| Slotkin, TA | 2 |
| Kreider, ML | 1 |
| Tate, CA | 1 |
| Yim, AJ | 1 |
| Miranda-Paiva, CM | 1 |
| Flório, JC | 1 |
| Oliveira, CA | 1 |
| Nasello, AG | 1 |
| Felicio, LF | 1 |
| Naef, L | 1 |
| Srivastava, L | 1 |
| Gratton, A | 1 |
| Hendrickson, H | 1 |
| Owens, SM | 1 |
| Walker, CD | 1 |
| Romero, E | 1 |
| Guaza, C | 1 |
| Castellano, B | 1 |
| Borrell, J | 1 |
| Lucchi, L | 1 |
| Covelli, V | 1 |
| Petkov, VV | 1 |
| Spano, PF | 1 |
| Trabucchi, M | 1 |
| Henderson, MG | 1 |
| McMillen, BA | 1 |
| Pérez-Otaño, I | 2 |
| Luquin, MR | 2 |
| Oset, C | 2 |
| Herrero, MT | 1 |
| Kupsch, A | 2 |
| Oertel, W | 2 |
| Obeso, JA | 2 |
| Del Río, J | 2 |
| Ali, SF | 2 |
| Holson, RR | 1 |
| Newport, GD | 1 |
| Slikker, W | 1 |
| Bowyer, JF | 1 |
| Alonso, SJ | 1 |
| Navarro, E | 1 |
| Rodriguez, M | 1 |
| Meyer, JS | 1 |
| Dupont, SA | 1 |
| Kovalev, GI | 1 |
| Kudrin, VS | 1 |
| Trofimov, SS | 1 |
| Ostrovskaia, RU | 1 |
| Robinson, SE | 1 |
| Guo, H | 1 |
| Maher, JR | 1 |
| McDowell, KP | 1 |
| Kunko, PM | 1 |
| Gorio, A | 1 |
| Malosio, ML | 1 |
| Vergani, L | 1 |
| Di Giulio, AM | 1 |
| Bonnin, A | 1 |
| de Miguel, R | 1 |
| Castro, JG | 1 |
| Ramos, JA | 1 |
| Fernandez-Ruiz, JJ | 1 |
| Silva-Araújo, A | 1 |
| Silva, MC | 1 |
| Simon, A | 1 |
| Nguyen-Legros, J | 1 |
| Tavares, MA | 1 |
| Sajnani, GG | 1 |
| Abreu, P | 1 |
| Castro, R | 1 |
| Muneoka, K | 1 |
| Mikuni, M | 1 |
| Ogawa, T | 1 |
| Kitera, K | 1 |
| Kamei, K | 1 |
| Takigawa, M | 1 |
| Takahashi, K | 1 |
| Watanabe, M | 1 |
| Nonaka, R | 1 |
| Hagino, Y | 1 |
| Kodama, Y | 1 |
| Schneider, ML | 1 |
| Clarke, AS | 1 |
| Kraemer, GW | 1 |
| Roughton, EC | 1 |
| Lubach, GR | 1 |
| Rimm-Kaufman, S | 1 |
| Schmidt, D | 1 |
| Ebert, M | 1 |
| Katakura, Y | 1 |
| Kishi, R | 1 |
| Ikeda, T | 1 |
| Miyake, H | 1 |
| Du, W | 1 |
| Aloyo, VJ | 1 |
| Pazdelski, PS | 1 |
| Harvey, JA | 1 |
| Peyronnet, J | 1 |
| Roux, JC | 1 |
| Geloën, A | 1 |
| Tang, LQ | 1 |
| Pequignot, JM | 1 |
| Lagercrantz, H | 1 |
| Dalmaz, Y | 1 |
| Devoto, P | 1 |
| Flore, G | 1 |
| Ibba, A | 1 |
| Fratta, W | 1 |
| Pani, L | 1 |
| Elsworth, JD | 1 |
| Morrow, BA | 1 |
| Roth, RH | 1 |
| Lee, BC | 1 |
| Bing, G | 1 |
| Jhoo, WK | 1 |
| Yoon, JM | 1 |
| Kang, KS | 1 |
| Shin, EJ | 1 |
| Kim, WK | 1 |
| Ko, KH | 1 |
| Kim, HC | 1 |
| Won, L | 1 |
| Bubula, N | 1 |
| Heller, A | 1 |
| Antonio, MT | 1 |
| López, N | 1 |
| Leret, ML | 1 |
| Trinidad Herrero, M | 1 |
| Rathbun, W | 1 |
| Druse, MJ | 1 |
| Fride, E | 1 |
| Weinstock, M | 1 |
| Fung, YK | 1 |
| Lau, YS | 1 |
| Yanai, J | 1 |
| Sze, PY | 1 |
| Iser, C | 1 |
| Melamed, E | 1 |
| Brioni, JD | 1 |
| Keller, EA | 1 |
| Levin, LE | 1 |
| Córdoba, N | 1 |
| Orsingher, OA | 1 |
| Guilarte, TR | 1 |
| Wagner, HN | 1 |
| Frost, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial of Adjunctive Siltuximab in Schizophrenia[NCT02796859] | Phase 1/Phase 2 | 30 participants (Anticipated) | Interventional | 2016-05-31 | Recruiting | ||
| An Open-Label Trial of Tocilizumab in Schizophrenia[NCT01696929] | Phase 1 | 8 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The Brief Assessment of Cognition in Schizophrenia (BACS) is the metric used to characterize cognition in this study. The BACS consists of 6 subscales: Verbal Memory (range 0-75), Working Memory (range 0-28), Motor Speed (range 0-100), Verbal Fluency (measure is total number of words generated in two 60 second trials), Attention and Processing speed (range 0-110), and Executive Function (range 0-22). For each subscale, higher scores reflect better cognition. For each subscale, a Standard Deviation Score was calculated based on normative data (Keefe et al. Norms and standardization of the Brief Assessment of Cognition in Schizophrenia (BACS). Schizophrenia Research 102 (2008) 108-115). The BACS composite score is calculated as the average Standard Deviation Score of the 6 subscale scores. The change in BACS composite score was calculated as the BACS composite score at 8 weeks minus the BACS composite score at baseline. (NCT01696929)
Timeframe: Change in BACS composite score from baseline to 8 weeks
| Intervention | Change in BACS Composite Score (Mean) |
|---|---|
| Tocilizumab | 0.7 |
The Positive and Negative Symptoms Scale (PANSS) is the metric used to characterize psychotic symptoms in this study. The PANSS consists of 30 items, each scored 1-7. The range for the PANSS total score is 30-210. There are 3 subscales - PANSS positive score (range 7-49), PANSS negative score (range 7-49), and PANSS general score (range 16-112). PANSS total score is the summation of these 3 subscales. Higher values for the total and subscale scores reflect more severe psychopathology. A positive change in PANSS total score reflects an increase in psychopathology. A negative change in PANSS total score reflects a decrease in psychopathology. (NCT01696929)
Timeframe: Change in PANSS total score from baseline to 8 weeks
| Intervention | Change in PANSS Total Score (Mean) |
|---|---|
| Tocilizumab | -2.6 |
52 other studies available for 3,4-dihydroxyphenylacetic acid and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Preventive role of regular low-intensity exercise during adolescence in schizophrenia model mice with abnormal behaviors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Behavior, Animal; Disease Models, Animal; Dopa | 2021 |
Maternal undernutrition during lactation alters nicotine reward and DOPAC/dopamine ratio in cerebral cortex in adolescent mice, but does not affect nicotine-induced nAChRs upregulation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Anima | 2018 |
Pre-gestational stress alters stress-response of pubertal offspring rat in sexually dimorphic and hemispherically asymmetric manner.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Catech | 2013 |
Dietary supplementation with resveratrol protects against striatal dopaminergic deficits produced by in utero LPS exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dietary Supplements; Disease Models, Anima | 2014 |
The effects of gestational and chronic atrazine exposure on motor behaviors and striatal dopamine in male Sprague-Dawley rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Atrazine; Behavior, Animal; Cognition; Corpus | 2015 |
The influence of aripiprazole and olanzapine on neurotransmitters level in frontal cortex of prenatally stressed rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Dopami | 2016 |
Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin such as schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Brain Diseases; Chromatography, High Press | 2009 |
Effect of prenatal exposure to diesel exhaust on dopaminergic system in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Circadian Rhythm; Dopamine; Female; Homovanillic Aci | 2009 |
Prenatal lipopolysaccharide does not accelerate progressive dopamine neuron loss in the rat as a result of normal aging.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; Analysis of Variance; Animals; Body Weight; Brai | 2009 |
Augmentation of cocaine-sensitized dopamine release in the nucleus accumbens of adult mice following prenatal cocaine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Hydr | 2009 |
Prenatal methamphetamine exposure affects the mesolimbic dopaminergic system and behavior in adult offspring.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Disease Mod | 2009 |
Modeling a sensitization stage and a precipitation stage for Parkinson's disease using prenatal and postnatal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Birth | 2010 |
Prenatal and lactational exposure to low-doses of bisphenol A alters brain monoamine concentration in adult mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Benzhydryl Compounds; Brain; Chromato | 2010 |
Effects of perinatal exposure to low dose of bisphenol A on anxiety like behavior and dopamine metabolites in brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amygdala; Animals; Anxiety; Benzhydryl Compounds; Dopamine; Endocrin | 2012 |
Presynaptic dopaminergic function is largely unaltered in mesolimbic and mesostriatal terminals of adult rats that were prenatally exposed to cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoreceptors; Cocaine; Corpus Striatum; Dopamine; Dopamine | 2003 |
Prenatal 3,4-methylenedioxymethamphetamine (ecstasy) exposure induces long-term alterations in the dopaminergic and serotonergic functions in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Age Fac | 2005 |
Altered mesencephalic dopaminergic populations in adulthood as a consequence of brief perinatal glucocorticoid exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Dexamethasone; Dopamine; Female; Glucocor | 2005 |
Alterations in central nervous system serotonergic and dopaminergic synaptic activity in adulthood after prenatal or neonatal chlorpyrifos exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain; Chlorpyrifos; Dopamine; Female; Ho | 2005 |
Critical prenatal and postnatal periods for persistent effects of dexamethasone on serotonergic and dopaminergic systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Developmental Disabilities; Dexamethasone; Dopamine; | 2006 |
A comparative study of morphine treatment regimen prior to mating and during late pregnancy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Brain | 2006 |
Maternal high fat diet during the perinatal period alters mesocorticolimbic dopamine in the adult rat offspring: reduction in the behavioral responses to repeated amphetamine administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Arousal; Central Nervous System Stimulant | 2008 |
Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Age Factors; Analysis of Variance; Animals; An | 2010 |
Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Age Factors; Analysis of Variance; Animals; An | 2010 |
Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Age Factors; Analysis of Variance; Animals; An | 2010 |
Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Age Factors; Analysis of Variance; Animals; An | 2010 |
Effects of ethanol, given during pregnancy, on the offspring dopaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dextroamphetamine; Dopamine; Ethanol; Fema | 1983 |
Changes in dopamine, serotonin and their metabolites in discrete brain areas of rat offspring after in utero exposure to cocaine or related drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amitriptyline; Amygdala; Analysis of Variance; Animals; Brain | 1993 |
Neurotoxicity induced by prenatal exposure to MPTP on the monoaminergic and peptidergic systems of the marmoset brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Callithrix; Dopamine; Enkephalin, Methionine; Female | 1995 |
Development of dopamine and N-methyl-D-aspartate systems in rat brain: the effect of prenatal phencyclidine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Female; | 1993 |
Permanent dopaminergic alterations in the n. accumbens after prenatal stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Dopamine; Female; Functional Laterality; H | 1994 |
Prenatal cocaine administration stimulates fetal brain tyrosine hydroxylase activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cocaine; Dopamine; Embryonic and Fetal Development; | 1993 |
[The sodium oxybutyrate and nooglutil correction of dopamine release in the striatum of prenatally alcoholized rat pups].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Ethanol; Female; Glutamates; Mal | 1993 |
Postnatal methadone exposure doe not prevent prenatal methadone-induced changes in striatal cholinergic neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Dopamine; Female; Hydroxyindoleacetic Acid; | 1996 |
Exposure to perinatal morphine promotes developmental changes in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Enkephalin, Methionine; Enkephalins; Female; In S | 1996 |
Effects of perinatal exposure to delta 9-tetrahydrocannabinol on the fetal and early postnatal development of tyrosine hydroxylase-containing neurons in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Brain; Dronabinol; Female; Gene Ex | 1996 |
The effects of prenatal exposure to cocaine on the dopaminergic cells in the rat retina. An immunocytochemical and neurochemical study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Homo | 1996 |
Pre/postnatal dopamine D1 receptor stimulation induces a differential reduction of serotonin levels in hippocampus and superior colliculus of puber rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Aging; A | 1997 |
Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Cortex; Aging; Analysis of Variance; Animals; Biogenic Monoa | 1997 |
Effects of prenatal methylazoxymethanol treatment on striatal dopaminergic systems in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Brain; Carrier Proteins; Corpus Striatum; | 1998 |
Prenatal stress alters brain biogenic amine levels in primates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Behavior, Animal; Biogenic Amines; Brain; Female; Ho | 1998 |
Effects of prenatal exposure to styrene on neurochemical levels in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Birth Weight; Brain; Brain Chemistry; Dop | 1999 |
Effects of prenatal cocaine exposure on amphetamine-induced dopamine release in the caudate nucleus of the adult rabbit.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Caudate Nucleus; Cocaine; Dopamine; Dopamine U | 1999 |
Prenatal hypoxia impairs the postnatal development of neural and functional chemoafferent pathway in rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Afferent Pathways; Animals; Body Temperature; Brain Stem; Catecholam | 2000 |
Lead intoxication during intrauterine life and lactation but not during adulthood reduces nucleus accumbens dopamine release as studied by brain microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Female; Lactation; Lead; Male; Microdialys | 2001 |
Prenatal cocaine exposure increases mesoprefrontal dopamine neuron responsivity to mild stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Electr | 2001 |
Prenatal exposure to magnetic field increases dopamine levels in the striatum of offspring.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Female; Fetus; Magnetics; Mice; | 2001 |
Fetal exposure to methamphetamine in utero stimulates development of serotonergic neurons in three-dimensional reaggregate tissue culture.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine-Related Disorders; Animals; Brain; Cell Aggregation; Cel | 2002 |
Pb and Cd poisoning during development alters cerebellar and striatal function in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Abnormalities, Drug-Induced; Animals; Animals, Newborn; Cadmium; Cer | 2002 |
Neurotoxic effect of prenatal exposure to MPTP on the dopaminergic systems of the marmoset brain.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Adolescent; Animals; C | 1992 |
Dopamine, serotonin, and acid metabolites in brain regions from the developing offspring of ethanol-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liqui | 1985 |
Alterations in behavioral and striatal dopamine asymmetries induced by prenatal stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Behavior, Animal; Body Weight; Caudate Nucleus | 1989 |
Effects of prenatal nicotine exposure on rat striatal dopaminergic and nicotinic systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Weight; Corpus Striatum; Cotinine; Female; Gestational | 1989 |
Studies on brain monoamine neurotransmitters in mice after prenatal exposure to barbiturate.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Barbiturates; Biogenic Amines; Brain; Brain Stem; Catechola | 1985 |
Reactivity to amphetamine in perinatally undernourished rats: behavioral and neurochemical correlates.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Amphetamine; Animals; Behavior, Animal; Brain | 1986 |
Effects of perinatal vitamin B6 deficiency on dopaminergic neurochemistry.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Weight; Chromatography, High Pressure Liquid; Corpus S | 1987 |