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3,4-dihydroxyphenylacetic acid and Chronic Illness

3,4-dihydroxyphenylacetic acid has been researched along with Chronic Illness in 22 studies

3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.

Research Excerpts

ExcerptRelevanceReference
"Intracerebral microdialysis was applied to monitor the neocortical extracellular levels of the aromatic amino acids phenylalanine, tyrosine, and tryptophan, the neurotransmitters dopamine (DA), noradrenaline (NA), and serotonin (5-HT), and the metabolites 3,4-dihydroxyphenylacetic acid (DOPAC) and 5-hydroxyindole-3-acetic acid (5-HIAA) in rats with various forms of experimental hepatic encephalopathy (HE)."3.69Neocortical dialysate monoamines of rats after acute, subacute, and chronic liver shunt. ( Bengtsson, F; Bergqvist, PB; Bosman, DK; Chamuleau, RA; Hjorth, S; Maas, MA; Vogels, BA, 1995)
"The content and turnover of dopamine, 3,4-dihydroxyphenylacetic acid and norepinephrine have been investigated in the superior cervical, coeliac and mesenteric ganglia of rats exposed to moderate normobaric hypoxia (10% O2 in N2) lasting for 2-28 days."3.67Long-term hypoxia increases the turnover of dopamine but not norepinephrine in rat sympathetic ganglia. ( Cottet-Emard, JM; Dalmaz, Y; Pequignot, JM; Peyrin, L; Tavitian, E, 1988)
"Rosiglitazone is a commonly prescribed insulin-sensitizing drug with a selective agonistic activity on the peroxisome proliferator-activated receptor-gamma (PPAR-gamma)."1.35PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson's disease. ( Caboni, P; Carboni, E; Carta, AR; Frau, L; Garau, A; Ibba, M; Schintu, N, 2009)
"Treatment with imipramine (10mg/kg i."1.33Behavioural and neurochemical effects induced by chronic mild stress applied to two different rat strains. ( Antoniou, K; Bekris, S; Daskas, S; Papadopoulou-Daifoti, Z, 2005)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19907 (31.82)18.7374
1990's5 (22.73)18.2507
2000's9 (40.91)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schintu, N1
Frau, L1
Ibba, M1
Caboni, P1
Garau, A1
Carboni, E1
Carta, AR1
Pais-Vieira, M1
Mendes-Pinto, MM1
Lima, D1
Galhardo, V1
Govitrapong, P1
Boontem, P1
Kooncumchoo, P1
Pinweha, S1
Namyen, J1
Sanvarinda, Y1
Vatanatunyakum, S1
Pacak, K2
Tjurmina, O1
Palkovits, M2
Goldstein, DS2
Koch, CA1
Hoff, T1
Chrousos, GP1
Kosten, TA1
Zhang, XY1
Kehoe, P1
Pardon, MC1
Hanoun, N1
Perez-Diaz, F1
Joubert, C1
Launay, JM1
Christen, Y1
Hamon, M1
Cohen-Salmon, C1
Bekris, S1
Antoniou, K1
Daskas, S1
Papadopoulou-Daifoti, Z1
Baksi, SN1
Hughes, MJ1
Bergqvist, PB1
Vogels, BA1
Bosman, DK1
Maas, MA1
Hjorth, S1
Chamuleau, RA1
Bengtsson, F1
Hantraye, P1
Guibert, B1
Biguet, NF1
Lavergne, A1
Leviel, V1
Prell, GD1
Green, JP1
Elkashef, AM1
Khandelwal, JK1
Linnoila, M1
Wyatt, RJ1
Lawson, WB1
Jaeger, AC1
Kaufmann, CA1
Kirch, DG1
Pestana, M1
Jardim, H1
Serrão, P1
Soares-da-Silva, P1
Guerra, L1
Fuertes, G1
Laorden, ML1
Milanés, MV1
Hildebrand, BE1
Svensson, TH1
Rothblat, DS1
Rubin, E1
Schneider, JS1
Armando, I1
Fukuhara, K1
Kvetnansky, R1
Kopin, IJ1
France, RD1
Urban, BJ1
Pelton, S1
Kilts, CD1
Hong, JS1
Nemeroff, CB1
Bagdy, G2
Perényi, A2
Frecska, E2
Révai, K2
Papp, Z1
Fekete, MI1
Arató, M1
Contreras, SA1
Maas, JW1
Seleshi, E1
Bowden, CL1
Dalmaz, Y1
Pequignot, JM1
Tavitian, E1
Cottet-Emard, JM1
Peyrin, L1
Cabib, S1
Kempf, E1
Schleef, C1
Mele, A1
Puglisi-Allegra, S1

Trials

1 trial available for 3,4-dihydroxyphenylacetic acid and Chronic Illness

ArticleYear
Urine and plasma levels of dopamine metabolites in response to apomorphine and neuroleptics in schizophrenics.
    Biological psychiatry, 1988, Volume: 24, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Apomorphine; Chronic Disease; Clinical Trials as Topic; Diben

1988

Other Studies

21 other studies available for 3,4-dihydroxyphenylacetic acid and Chronic Illness

ArticleYear
PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson's disease.
    The European journal of neuroscience, 2009, Volume: 29, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catalepsy; CD11b Antigen; Chromatography, High Pressure Liq

2009
Cognitive impairment of prefrontal-dependent decision-making in rats after the onset of chronic pain.
    Neuroscience, 2009, Jul-07, Volume: 161, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amygdala; Animals; Chronic Disease; Cognition; Decision Making; Dise

2009
Increased blood oxidative stress in amphetamine users.
    Addiction biology, 2010, Volume: 15, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Amphetamine-Related Disorders; Catalase; Chronic Disease; Dop

2010
Chronic hypercortisolemia inhibits dopamine synthesis and turnover in the nucleus accumbens: an in vivo microdialysis study.
    Neuroendocrinology, 2002, Volume: 76, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Chronic Disea

2002
Chronic neonatal isolation stress enhances cocaine-induced increases in ventral striatal dopamine levels in rat pups.
    Brain research. Developmental brain research, 2003, Mar-14, Volume: 141, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Chronic Disease; Cocaine; Cocaine-Related

2003
Long-term treatment with the antioxidant drug EGb 761 at senescence restored some neurobehavioral effects of chronic ultramild stress exposure seen in young mice.
    Neurobiology of aging, 2004, Volume: 25, Issue:8

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Antioxidants; Behavior, Animal; Brain; Brain Chemist

2004
Behavioural and neurochemical effects induced by chronic mild stress applied to two different rat strains.
    Behavioural brain research, 2005, Jun-03, Volume: 161, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Beh

2005
Chronic vitamin D deficiency in the weanling rat alters catecholamine metabolism in the cortex.
    Brain research, 1982, Jun-24, Volume: 242, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Cortex; Cholecalciferol; Chronic Disease; Corpus S

1982
Neocortical dialysate monoamines of rats after acute, subacute, and chronic liver shunt.
    Journal of neurochemistry, 1995, Volume: 64, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acute Disease; Amino Acids; Ammonia; Animals; Biogenic Monoamines; B

1995
TH mRNA over-expression in rats with chronic excitotoxic striatal lesions.
    Neuroreport, 1994, Dec-20, Volume: 5, Issue:18

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Diseases; Caudate Nucleus; Chronic Disease; Co

1994
The relationship between urine excretion and biogenic amines and their metabolites in cerebrospinal fluid of schizophrenic patients.
    Schizophrenia research, 1996, Volume: 19, Issue:2-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Biogenic Amines; Chronic Disease; Drinking; Female; Histamine

1996
Reduced urinary excretion of dopamine and metabolites in chronic renal parenchymal disease.
    Kidney & blood pressure research, 1998, Volume: 21, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Biopsy; Catechol O-Methyltransferase; Chromatography, H

1998
Noradrenergic and dopaminergic activity in the hypothalamic paraventricular nucleus after naloxone-induced morphine withdrawal.
    Neuroendocrinology, 2000, Volume: 71, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Chroni

2000
Intraaccumbal mecamylamine infusion does not affect dopamine output in the nucleus accumbens of chronically nicotine-treated rats.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:8-9

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Chronic Disease; Dopamine; Extracellular

2000
Effects of chronic alcohol ingestion on the mesostriatal dopamine system in the rat.
    Neuroscience letters, 2001, Mar-09, Volume: 300, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol-Induced Disorders, Nervous System; Animals; Carrier Proteins

2001
Noradrenergic activation in the paraventricular nucleus during acute and chronic immobilization stress in rats: an in vivo microdialysis study.
    Brain research, 1992, Aug-28, Volume: 589, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acute Disease; Animals; Chronic Disease; Dialysis; Disease Models, A

1992
CSF monoamine metabolites in chronic pain.
    Pain, 1987, Volume: 31, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Back Pain; Biogenic Amines; Chronic Disease; Depressive

1987
Decrease in dopamine, its metabolites and noradrenaline in cerebrospinal fluid of schizophrenic patients after withdrawal of long-term neuroleptic treatment.
    Psychopharmacology, 1985, Volume: 85, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antipsychotic Agents; Chronic Disease; Dopamine; Female; Halo

1985
CSF dopamine turnover and positive schizophrenic symptoms after withdrawal of long-term neuroleptic treatment.
    Psychiatry research, 1985, Volume: 16, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antipsychotic Agents; Brain; Chronic Disease; Dopamine; Femal

1985
Long-term hypoxia increases the turnover of dopamine but not norepinephrine in rat sympathetic ganglia.
    Journal of the autonomic nervous system, 1988, Volume: 24, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chronic Disease; Dopamine; Ganglia, Sympathetic; Hypoxia; M

1988
Different effects of acute and chronic stress on two dopamine-mediated behaviors in the mouse.
    Physiology & behavior, 1988, Volume: 43, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acute Disease; Animals; Apomorphine; Brain; Caudate Nucleus; Chronic

1988