3,4-dihydroxyphenylacetic acid has been researched along with Brain Disorders in 15 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
| Excerpt | Relevance | Reference |
|---|---|---|
| " All of these effects of ATR were observed at levels that were not toxic to the tissue, as LDH release into the medium (lactate dehydrogenase, an index of non-specific cytotoxicity) was not affected by ATR." | 1.34 | Dopaminergic toxicity of the herbicide atrazine in rat striatal slices. ( Carr, RL; Filipov, NM; Sistrunk, SC; Stewart, MA, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 8 (53.33) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Winter, C | 1 |
| Djodari-Irani, A | 1 |
| Sohr, R | 1 |
| Morgenstern, R | 1 |
| Feldon, J | 1 |
| Juckel, G | 1 |
| Meyer, U | 1 |
| Moroz, IA | 1 |
| Peciña, S | 1 |
| Schallert, T | 1 |
| Stewart, J | 1 |
| Filipov, NM | 1 |
| Stewart, MA | 1 |
| Carr, RL | 1 |
| Sistrunk, SC | 1 |
| Melamed, E | 1 |
| Hefti, F | 1 |
| Bird, ED | 1 |
| Hantraye, P | 1 |
| Guibert, B | 1 |
| Biguet, NF | 1 |
| Lavergne, A | 1 |
| Leviel, V | 1 |
| Obata, T | 1 |
| Yamanaka, Y | 1 |
| Kondoh, T | 1 |
| Low, WC | 1 |
| Hossain, MA | 1 |
| Weiner, N | 1 |
| Lan, J | 1 |
| Jiang, DH | 1 |
| Klivenyi, P | 1 |
| St Clair, D | 1 |
| Wermer, M | 1 |
| Yen, HC | 1 |
| Oberley, T | 1 |
| Yang, L | 1 |
| Flint Beal, M | 1 |
| Xia, XG | 1 |
| Schmidt, N | 1 |
| Teismann, P | 1 |
| Ferger, B | 1 |
| Schulz, JB | 1 |
| Gordon, K | 1 |
| Statman, D | 1 |
| Johnston, MV | 1 |
| Robinson, TE | 2 |
| Becker, JB | 1 |
| Silverstein, FS | 1 |
| Castañeda, E | 1 |
| Whishaw, IQ | 1 |
| Bradbury, AJ | 1 |
| Costall, B | 1 |
| Domeney, AM | 1 |
| Testa, B | 1 |
| Jenner, PG | 1 |
| Marsden, CD | 1 |
| Naylor, RJ | 1 |
| Fibiger, HC | 1 |
| LePiane, FG | 1 |
| Jakubovic, A | 1 |
| Phillips, AG | 1 |
1 review available for 3,4-dihydroxyphenylacetic acid and Brain Disorders
| Article | Year |
|---|---|
Desferrioxamine and vitamin E protect against iron and MPTP-induced neurodegeneration in mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Disease | 1997 |
14 other studies available for 3,4-dihydroxyphenylacetic acid and Brain Disorders
| Article | Year |
|---|---|
Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin such as schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Brain Diseases; Chromatography, High Press | 2009 |
Sparing of behavior and basal extracellular dopamine after 6-hydroxydopamine lesions of the nigrostriatal pathway in rats exposed to a prelesion sensitizing regimen of amphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Behav | 2004 |
Dopaminergic toxicity of the herbicide atrazine in rat striatal slices.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atrazine; Brain Diseases; Corpus Striatum; Dopamine; Dopami | 2007 |
Huntington chorea is not associated with hyperactivity of nigrostriatal dopaminergic neurons: studies in postmortem tissues and in rats with kainic acid lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Dopamine; Female; Homovani | 1982 |
TH mRNA over-expression in rats with chronic excitotoxic striatal lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Diseases; Caudate Nucleus; Chronic Disease; Co | 1994 |
Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation by monoamine oxidase inhibitor in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Diseases; Corpus Striatum; Dopamine; Free Radi | 1995 |
Glutamate uptake blockade induces striatal dopamine release in 6-hydroxydopamine rats with intrastriatal grafts: evidence for host modulation of transplanted dopamine neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Diseases; Brain Tissue Transplantation; Corpus | 1994 |
Dopaminergic functional supersensitivity: effects of chronic L-dopa and carbidopa treatment in an animal model of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biopterins; Brain Diseases; Carbidopa; Corpus Striatum; Cyc | 1993 |
Manganese superoxide dismutase overexpression attenuates MPTP toxicity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic | 1998 |
Dopamine mediates striatal malonate toxicity via dopamine transporter-dependent generation of reactive oxygen species and D2 but not D1 receptor activation.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Benzazepines; Brain Diseases; Carbido | 2001 |
Transient hypoxia alters striatal catecholamine metabolism in immature brain: an in vivo microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain Diseases; Corpus Striatum; Dialysis | 1990 |
Changes in striatal dopamine neurotransmission assessed with microdialysis following recovery from a bilateral 6-OHDA lesion: variation as a function of lesion size.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Brain Diseases; Corpus Striatum; Dialysis; Dop | 1990 |
The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic | 1985 |
The role of dopamine in intracranial self-stimulation of the ventral tegmental area.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Dopamine; Electric Stimula | 1987 |