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3,4-dihydroxyphenylacetic acid and Autism

3,4-dihydroxyphenylacetic acid has been researched along with Autism in 8 studies

3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.

Research Excerpts

ExcerptRelevanceReference
"Fifteen children with autism were treated with 60 mg d,l-fenfluramine (FEN) or placebo in a double-blind A-B-A protocol followed immediately by double-blind placebo-controlled crossover administration of FEN (total duration 62 weeks)."9.07Clinical and neurochemical effects of fenfluramine in children with autism. ( Cook, EH; Freedman, DX; Heller, W; Leventhal, BL; Morford, M; Ravitz, AJ, 1993)
"Fifteen children with autism were treated with 60 mg d,l-fenfluramine (FEN) or placebo in a double-blind A-B-A protocol followed immediately by double-blind placebo-controlled crossover administration of FEN (total duration 62 weeks)."5.07Clinical and neurochemical effects of fenfluramine in children with autism. ( Cook, EH; Freedman, DX; Heller, W; Leventhal, BL; Morford, M; Ravitz, AJ, 1993)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's4 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hameury, L1
Roux, S2
Barthélémy, C6
Adrien, JL1
Desombre, H1
Sauvage, D1
Garreau, B3
Lelord, G6
Leventhal, BL1
Cook, EH1
Morford, M1
Ravitz, AJ1
Heller, W1
Freedman, DX1
Martineau, J3
Jouve, J4
Muh, JP3
Bruneau, N3
Cottet-Eymard, JM1
Domenech-Jouve, J1
Peyrin, L1
Launay, JM1
Bursztejn, C1
Ferrari, P1
Dreux, C1
Braconnier, A1
Zarifian, E1
Lancrenon, S1
Fermanian, J1

Trials

3 trials available for 3,4-dihydroxyphenylacetic acid and Autism

ArticleYear
Clinical and neurochemical effects of fenfluramine in children with autism.
    The Journal of neuropsychiatry and clinical neurosciences, 1993,Summer, Volume: 5, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Autistic Disorder; Child; Child Behavior Disorders; Chil

1993
Auditory evoked potential modifications according to clinical and biochemical responsiveness to fenfluramine treatment in children with autistic behavior.
    Neuropsychobiology, 1989, Volume: 21, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Autistic Disorder; Child; Child, Preschool; Dopamine; Evoked Potenti

1989
Urinary dopamine metabolites as indicators of the responsiveness to fenfluramine treatment in children with autistic behavior.
    Journal of autism and developmental disorders, 1989, Volume: 19, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Autistic Disorder; Child; Child, Preschool; Dopamine; Double-Blind M

1989

Other Studies

5 other studies available for 3,4-dihydroxyphenylacetic acid and Autism

ArticleYear
Quantified multidimensional assessment of autism and other pervasive developmental disorders. Application for bioclinical research.
    European child & adolescent psychiatry, 1995, Volume: 4, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Autistic Disorder; Brain; Child; Child Development Disor

1995
Monoamines (serotonin and catecholamines) and their derivatives in infantile autism: age-related changes and drug effects.
    Developmental medicine and child neurology, 1992, Volume: 34, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Autistic Disorder; Catecholamines; Child; Child Develop

1992
[Development in the metabolism of dopamine and its derivatives. Application to gross development disorders].
    Neurophysiologie clinique = Clinical neurophysiology, 1992, Volume: 22, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Autistic Disorder; Child; Child, Presch

1992
Urinary free and conjugated catecholamines and metabolites in autistic children.
    Journal of autism and developmental disorders, 1988, Volume: 18, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Autistic Disorder; Catecholamines; Child; Child, Preschool; Dopamine

1988
Catecholamines metabolism in infantile autism: a controlled study of 22 autistic children.
    Journal of autism and developmental disorders, 1987, Volume: 17, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Autistic Disorder; Blood Platelets; Catecholamines; Chil

1987