3,4-dihydroxyphenylacetic acid has been researched along with Anterior Horn Cell Disease in 1 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Excerpt | Relevance | Reference |
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" VU0364770 showed efficacy alone or when administered in combination with L-DOPA or an adenosine 2A (A2A) receptor antagonist currently in clinical development (preladenant)." | 1.38 | The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease. ( Amalric, M; Blobaum, AL; Bode, J; Bridges, TM; Bubser, M; Conn, PJ; Daniels, JS; Dickerson, JW; Engers, DW; Hopkins, CR; Italiano, K; Jadhav, S; Jones, CK; Lindsley, CW; Morrison, RD; Niswender, CM; Thompson, AD; Turle-Lorenzo, N, 2012) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Jones, CK | 1 |
Bubser, M | 1 |
Thompson, AD | 1 |
Dickerson, JW | 1 |
Turle-Lorenzo, N | 1 |
Amalric, M | 1 |
Blobaum, AL | 1 |
Bridges, TM | 1 |
Morrison, RD | 1 |
Jadhav, S | 1 |
Engers, DW | 1 |
Italiano, K | 1 |
Bode, J | 1 |
Daniels, JS | 1 |
Lindsley, CW | 1 |
Hopkins, CR | 1 |
Conn, PJ | 1 |
Niswender, CM | 1 |
1 other study available for 3,4-dihydroxyphenylacetic acid and Anterior Horn Cell Disease
Article | Year |
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The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Brain; Calcium Signaling | 2012 |