3,4-dihydroxyphenylacetic acid has been researched along with Amphetamine-Related Disorders in 13 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Amphetamine-Related Disorders: Disorders related or resulting from use of amphetamines.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lobeline is currently being evaluated in clinical trials as a methamphetamine abuse treatment." | 3.76 | Lobelane inhibits methamphetamine-evoked dopamine release via inhibition of the vesicular monoamine transporter-2. ( Crooks, PA; Deaciuc, G; Dwoskin, LP; Krishnamurthy, S; Nickell, JR; Norrholm, S; Siripurapu, KB; Zheng, G, 2010) |
| " The period of escalating doses (EDs) is likely associated with development of tolerance to aspects of METH's pharmacologic and toxic effects but the relative contributions of pharmacokinetic and pharmacodynamic factors have not been well defined." | 1.33 | Escalating dose pretreatment induces pharmacodynamic and not pharmacokinetic tolerance to a subsequent high-dose methamphetamine binge. ( Cho, AK; Kuczenski, R; Lacan, G; Melega, WP; O'Neil, ML; Segal, DS, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Marusich, JA | 1 |
| Gay, EA | 1 |
| Watson, SL | 1 |
| Blough, BE | 1 |
| Taepavarapruk, P | 1 |
| Butts, KA | 1 |
| Phillips, AG | 1 |
| Janphet, S | 1 |
| Nudmamud-Thanoi, S | 1 |
| Thanoi, S | 1 |
| Schwendt, M | 1 |
| Rocha, A | 1 |
| See, RE | 1 |
| Pacchioni, AM | 1 |
| McGinty, JF | 1 |
| Kalivas, PW | 1 |
| Govitrapong, P | 1 |
| Boontem, P | 1 |
| Kooncumchoo, P | 1 |
| Pinweha, S | 1 |
| Namyen, J | 1 |
| Sanvarinda, Y | 1 |
| Vatanatunyakum, S | 1 |
| Nickell, JR | 2 |
| Krishnamurthy, S | 1 |
| Norrholm, S | 1 |
| Deaciuc, G | 1 |
| Siripurapu, KB | 2 |
| Zheng, G | 1 |
| Crooks, PA | 2 |
| Dwoskin, LP | 2 |
| Beckmann, JS | 1 |
| Horton, DB | 1 |
| Denehy, ED | 1 |
| Vartak, A | 1 |
| Bardo, MT | 1 |
| Good, RL | 1 |
| Liang, LP | 1 |
| Patel, M | 1 |
| Radcliffe, RA | 1 |
| Pereira, FC | 1 |
| Imam, SZ | 1 |
| Gough, B | 1 |
| Newport, GD | 1 |
| Ribeiro, CF | 1 |
| Slikker, W | 1 |
| Macedo, TR | 1 |
| Ali, SF | 2 |
| O'Neil, ML | 1 |
| Kuczenski, R | 1 |
| Segal, DS | 1 |
| Cho, AK | 1 |
| Lacan, G | 1 |
| Melega, WP | 1 |
| Kita, T | 1 |
| Matsunari, Y | 1 |
| Saraya, T | 1 |
| Shimada, K | 1 |
| O'Hara, K | 1 |
| Kubo, K | 1 |
| Wagner, GC | 1 |
| Nakashima, T | 1 |
| Won, L | 1 |
| Bubula, N | 1 |
| Heller, A | 1 |
| Itzhak, Y | 1 |
13 other studies available for 3,4-dihydroxyphenylacetic acid and Amphetamine-Related Disorders
| Article | Year |
|---|---|
Alpha-pyrrolidinopentiophenone and mephedrone self-administration produce differential neurochemical changes following short- or long-access conditions in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine-Related Disorders; Animals; Brain; Central Nervous Syste | 2021 |
Dopamine and glutamate interaction mediates reinstatement of drug-seeking behavior by stimulation of the ventral subiculum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine-Related Disorders; Animals; Central Nervous System Stimu | 2014 |
Alteration of catecholamine concentrations in rat testis after methamphetamine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine-Related Disorders; Animals; Chromatography, High Pressur | 2017 |
Extended methamphetamine self-administration in rats results in a selective reduction of dopamine transporter levels in the prefrontal cortex and dorsal striatum not accompanied by marked monoaminergic depletion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine-Related Disorders; Animals; Biogenic Monoamines; Brain C | 2009 |
Increased blood oxidative stress in amphetamine users.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Amphetamine-Related Disorders; Catalase; Chronic Disease; Dop | 2010 |
Lobelane inhibits methamphetamine-evoked dopamine release via inhibition of the vesicular monoamine transporter-2.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine-Related Disorders; Animals; Corpus Striatum; Dopamine; D | 2010 |
The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aconitine; Amphetamine-Related Disorders; Animals; Behavior, Animal; | 2010 |
Mouse strain- and age-dependent effects of binge methamphetamine on dopaminergic signaling.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Amphetamine-Related Disorders; Animals; Basal Ganglia; | 2011 |
Acute changes in dopamine release and turnover in rat caudate nucleus following a single dose of methamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acute Disease; Amphetamine-Related Disorders; Animals; Caudate Nucle | 2002 |
Escalating dose pretreatment induces pharmacodynamic and not pharmacokinetic tolerance to a subsequent high-dose methamphetamine binge.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Amphetamine-Related Disorders; Animals; Body Temperatur | 2006 |
Methamphetamine-induced striatal dopamine release, behavior changes and neurotoxicity in BALB/c mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine-Related Disorders; Animals; Behavior, Animal; Body Tempe | 2000 |
Fetal exposure to methamphetamine in utero stimulates development of serotonergic neurons in three-dimensional reaggregate tissue culture.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine-Related Disorders; Animals; Brain; Cell Aggregation; Cel | 2002 |
Behavioral consequences of methamphetamine-induced neurotoxicity in mice: relevance to the psychopathology of methamphetamine addiction.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine-Related Disorders; Animals; Behavior, Animal; Binding Si | 2002 |