3,4-dihydroxyphenylacetic acid has been researched along with Alcoholism in 23 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Altogether, this indicates that semaglutide reduces alcohol drinking behaviours, possibly via a reduction in alcohol-induced reward and NAc dependent mechanisms." | 4.31 | Semaglutide reduces alcohol intake and relapse-like drinking in male and female rats. ( Aranäs, C; Blid Sköldheden, S; Edvardsson, CE; Jerlhag, E; Shevchouk, OT; Tufvesson-Alm, M; Vallöf, D; Witley, S; Zentveld, L; Zhang, Q, 2023) |
| " After chronic alcoholism, there was a decrease in the ratio of dihydroxyphenylacetic acid (DOPA) and homovanillic acid (HVA) to dopamine in the nucleus accumbens and striatum in rats subjected to alcoholism, as compared with intact controls." | 3.72 | Mechanisms of the influences of the central administration of substance P on ethanol consumption in chronically alcoholic rats. ( Bychkov, ER; Dambinova, SA; Lebedev, AA; Nikolaev, SV, 2003) |
| " There were significant, negative correlations between interview-derived lifetime aggression scores and cerebrospinal fluid concentrations of both the serotonin metabolite 5-hydroxyindoleacetic acid and the dopamine metabolite homovanillic acid." | 3.68 | Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls. ( Adinoff, B; Goldman, D; Lamparski, D; Limson, R; Linnoila, M; Ravitz, B; Roy, A, 1991) |
| " Dose-response curves for DA and 5-HT release indicated no marked difference in the sensitivity to ethanol between the lines." | 1.28 | Ethanol enhances the release of dopamine and serotonin in the nucleus accumbens of HAD and LAD lines of rats. ( Li, TK; Lumeng, L; McBride, WJ; Yoshimoto, K, 1992) |
| "The dose-response curve for morphine-induced stimulation of striatal dopamine metabolism was shifted to the right in mice which had been withdrawn for 24 hours after chronic consumption of an ethanol-containing liquid diet." | 1.26 | Alterations in opiate receptor function after chronic ethanol exposure. ( Hoffman, PL; Tabakoff, B; Urwyler, S, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (17.39) | 18.7374 |
| 1990's | 12 (52.17) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Aranäs, C | 1 |
| Edvardsson, CE | 1 |
| Shevchouk, OT | 1 |
| Zhang, Q | 1 |
| Witley, S | 1 |
| Blid Sköldheden, S | 1 |
| Zentveld, L | 1 |
| Vallöf, D | 1 |
| Tufvesson-Alm, M | 1 |
| Jerlhag, E | 1 |
| Hirth, N | 1 |
| Meinhardt, MW | 1 |
| Noori, HR | 1 |
| Salgado, H | 1 |
| Torres-Ramirez, O | 1 |
| Uhrig, S | 1 |
| Broccoli, L | 1 |
| Vengeliene, V | 1 |
| Roßmanith, M | 1 |
| Perreau-Lenz, S | 1 |
| Köhr, G | 1 |
| Sommer, WH | 1 |
| Spanagel, R | 1 |
| Hansson, AC | 1 |
| Ward, RJ | 1 |
| Colivicchi, MA | 1 |
| Allen, R | 1 |
| Schol, F | 1 |
| Lallemand, F | 1 |
| de Witte, P | 1 |
| Ballini, C | 1 |
| Corte, LD | 1 |
| Dexter, D | 1 |
| Nikolaev, SV | 2 |
| Bychkov, ER | 2 |
| Lebedev, AA | 2 |
| Dambinova, SA | 2 |
| Ojanen, S | 1 |
| Koistinen, M | 1 |
| Bäckström, P | 1 |
| Kankaanpää, A | 1 |
| Tuomainen, P | 1 |
| Hyytiä, P | 1 |
| Kiianmaa, K | 1 |
| Quintanilla, ME | 1 |
| Bustamante, D | 1 |
| Tampier, L | 1 |
| Israel, Y | 1 |
| Herrera-Marschitz, M | 1 |
| Murphy, JM | 2 |
| McBride, WJ | 3 |
| Lumeng, L | 3 |
| Li, TK | 3 |
| Hoffman, PL | 2 |
| Urwyler, S | 1 |
| Tabakoff, B | 1 |
| Barbaccia, ML | 1 |
| Bosio, A | 1 |
| Lucchi, L | 1 |
| Spano, PF | 1 |
| Trabucchi, M | 1 |
| Blanchard, BA | 1 |
| Glick, SD | 1 |
| Hegarty, AA | 1 |
| Vogel, WH | 1 |
| Philpot, RM | 1 |
| Kirstein, CL | 1 |
| Anokhina, IP | 1 |
| Vertinskaia, AG | 1 |
| Vekshina, NL | 1 |
| Nebarakova, TP | 1 |
| Ovchinnikov, IV | 1 |
| Druzhina, EV | 1 |
| Ovchinnikova, OI | 1 |
| Diana, M | 2 |
| Gessa, GL | 3 |
| Rossetti, ZL | 2 |
| Yoshimoto, K | 1 |
| Pellegrino, SM | 1 |
| Druse, MJ | 1 |
| Melis, F | 1 |
| Carboni, S | 1 |
| Limson, R | 1 |
| Goldman, D | 1 |
| Roy, A | 1 |
| Lamparski, D | 1 |
| Ravitz, B | 1 |
| Adinoff, B | 1 |
| Linnoila, M | 1 |
| Wahlström, G | 1 |
| Magnusson, O | 1 |
| Nordberg, A | 1 |
| Stenström, A | 1 |
| Tiger, G | 1 |
| Fadda, F | 1 |
| Colombo, G | 1 |
| Eisenhofer, G | 1 |
| Szabo, G | 1 |
23 other studies available for 3,4-dihydroxyphenylacetic acid and Alcoholism
| Article | Year |
|---|---|
Semaglutide reduces alcohol intake and relapse-like drinking in male and female rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Dopamine; Ethanol; Exenatide; | 2023 |
Convergent evidence from alcohol-dependent humans and rats for a hyperdopaminergic state in protracted abstinence.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Alcohol Abstinence; Alcoholism; Animals; Benzazepines; | 2016 |
Neuro-inflammation induced in the hippocampus of 'binge drinking' rats may be mediated by elevated extracellular glutamate content.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Amino Acids; Animals; Biogenic Monoamines; Conditioning, | 2009 |
[The influence of substance P central administration on ethanol intake in rats chronically exposed to alcohol].
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Corpus Striatum; Dopamine; Dr | 2002 |
Differential behavioural sensitization to intermittent morphine treatment in alcohol-preferring AA and alcohol-avoiding ANA rats: role of mesolimbic dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Chromatography, High Pressure Liquid; Dopamine; | 2003 |
Mechanisms of the influences of the central administration of substance P on ethanol consumption in chronically alcoholic rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Dopamine; Ethanol; Homovanill | 2003 |
Dopamine release in the nucleus accumbens (shell) of two lines of rats selectively bred to prefer or avoid ethanol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Anesthesia, Inhalation; Animals; Breed | 2007 |
Monoamine and metabolite levels in CNS regions of the P line of alcohol-preferring rats after acute and chronic ethanol treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholic Intoxication; Alcoholism; Animals; Brain Chemistry; Choice | 1983 |
Alterations in opiate receptor function after chronic ethanol exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Caudate Nucleus; Corpus Striatum; Dihydromorphi | 1982 |
Neuronal mechanisms regulating ethanol effects on the dopaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Dopamine; Ethanol; Haloperidol; Humans; Male; M | 1982 |
Sex differences in mesolimbic dopamine responses to ethanol and relationship to ethanol intake in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Arousal; Corpus Striatum; Dos | 1995 |
Modulation of the stress response by ethanol in the rat frontal cortex.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Cerebral Cortex; Dopamine; Dose-Response Relati | 1993 |
The effects of repeated alcohol exposure on the neurochemistry of the periadolescent nucleus accumbens septi.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Alcoholism; Animals; Dopamine; Dose-Response Relationship, Dr | 1998 |
[Hereditary alcoholism: some neurochemical and genetic mechanisms].
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Alleles; Brain; Dihydroxyphenylalanine; DNA; Genetic Dis | 1999 |
Lack of tolerance to ethanol-induced stimulation of mesolimbic dopamine system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholic Intoxication; Alcoholism; Animals; Corpus Striatum; Dopami | 1992 |
Ethanol enhances the release of dopamine and serotonin in the nucleus accumbens of HAD and LAD lines of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Dopamine; Dose-Response Relationship, Drug; Eth | 1992 |
The effects of chronic ethanol consumption on the mesolimbic and nigrostriatal dopamine systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Benzazepines; Brain Mapping; Corpus Striatum; D | 1992 |
Alcohol withdrawal in rats is associated with a marked fall in extraneuronal dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Withdrawal Delirium; Alcoholism; Animals; Corpus Striatum; D | 1992 |
Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aggression; Alcoholism; Homovanillic Acid; Humans; Hydroxyind | 1991 |
Temporal studies of the inhibition of voluntary ethanol intake in the rat induced by intermittent ethanol treatment and some long term neurochemical consequences.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Brain; Brain Mapping; Dopamin | 1991 |
Genetic sensitivity to effect of ethanol on dopaminergic system in alcohol preferring rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Brain; Caudate Nucleus; Dopamine; Ethanol; Fron | 1991 |
Opposite changes in turnover of noradrenaline and dopamine in the CNS of ethanol-dependent mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Brain; Catecholamines; Dopamine; Heart; Male; M | 1990 |
Contents of monoamines in forebrain regions of alcohol-preferring (P) and -nonpreferring (NP) lines of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Biogenic Amines; Brain; Cereb | 1987 |