Compounds > 3,4-dihydroxyphenylacetic acid
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3,4-dihydroxyphenylacetic acid and Alcohol Drinking

3,4-dihydroxyphenylacetic acid has been researched along with Alcohol Drinking in 29 studies

3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.

Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.

Research Excerpts

ExcerptRelevanceReference
"Altogether, this indicates that semaglutide reduces alcohol drinking behaviours, possibly via a reduction in alcohol-induced reward and NAc dependent mechanisms."4.31Semaglutide reduces alcohol intake and relapse-like drinking in male and female rats. ( Aranäs, C; Blid Sköldheden, S; Edvardsson, CE; Jerlhag, E; Shevchouk, OT; Tufvesson-Alm, M; Vallöf, D; Witley, S; Zentveld, L; Zhang, Q, 2023)
" After chronic alcoholism, there was a decrease in the ratio of dihydroxyphenylacetic acid (DOPA) and homovanillic acid (HVA) to dopamine in the nucleus accumbens and striatum in rats subjected to alcoholism, as compared with intact controls."3.72Mechanisms of the influences of the central administration of substance P on ethanol consumption in chronically alcoholic rats. ( Bychkov, ER; Dambinova, SA; Lebedev, AA; Nikolaev, SV, 2003)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19905 (17.24)18.7374
1990's14 (48.28)18.2507
2000's9 (31.03)29.6817
2010's0 (0.00)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Aranäs, C1
Edvardsson, CE1
Shevchouk, OT1
Zhang, Q1
Witley, S1
Blid Sköldheden, S1
Zentveld, L1
Vallöf, D1
Tufvesson-Alm, M1
Jerlhag, E1
Philpot, RM1
Wecker, L1
Kirstein, CL1
Nikolaev, SV2
Bychkov, ER2
Lebedev, AA2
Dambinova, SA2
Tuomainen, P1
Patsenka, A1
Hyytiä, P1
Grinevich, V1
Kiianmaa, K6
Maul, B1
Krause, W1
Pankow, K1
Becker, M1
Gembardt, F1
Alenina, N1
Walther, T1
Bader, M1
Siems, WE1
Carlson, JN1
Drew Stevens, K1
Quintanilla, ME1
Bustamante, D1
Tampier, L1
Israel, Y1
Herrera-Marschitz, M1
Nurmi, M2
Nykänen, I1
Sinclair, JD2
Adell, A2
Myers, RD2
Blanchard, BA2
Glick, SD2
Steindorf, S1
Wang, S1
Woods, JM1
Druse, MJ1
Honkanen, A2
Ahtee, L2
Korpi, ER1
Yoshimoto, K1
Kaneda, S1
Kawai, Y1
Ueda, S1
Takeuchi, Y1
Matsushita, H1
Yuri, K1
Yasuhara, M1
Mikkola, JA1
Piepponen, TP1
Keung, WM1
Yukhananov, RY1
Tennilä, TM1
Miroshnicenko, TI1
Kudrin, VS1
Ushakov, AN1
Melnik, EI1
Michaleva, II1
Rayevsky, KS1
Airaksinen, MM1
Maisky, AI1
Wahlström, G1
Magnusson, O1
Nordberg, A1
Stenström, A1
Tiger, G1
Clarren, SK1
Astley, SJ1
Bowden, DM1
Lai, H1
Milam, AH1
Rudeen, PK1
Shoemaker, WJ1
Fadda, F3
Mosca, E3
Colombo, G3
Gessa, GL3
Maisky, A1
Murphy, JM2
McBride, WJ2
Lumeng, L2
Li, TK2
Aalto, J1
Hilakivi, LA1
Hilakivi, I1

Other Studies

29 other studies available for 3,4-dihydroxyphenylacetic acid and Alcohol Drinking

ArticleYear
Semaglutide reduces alcohol intake and relapse-like drinking in male and female rats.
    EBioMedicine, 2023, Volume: 93

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Dopamine; Ethanol; Exenatide;

2023
Repeated ethanol exposure during adolescence alters the developmental trajectory of dopaminergic output from the nucleus accumbens septi.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2009, Volume: 27, Issue:8

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Alcohol Drinking; Animals; Central Nervous System Depres

2009
[The influence of substance P central administration on ethanol intake in rats chronically exposed to alcohol].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2002, Volume: 88, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Corpus Striatum; Dopamine; Dr

2002
Extracellular levels of dopamine in the nucleus accumbens in AA and ANA rats after reverse microdialysis of ethanol into the nucleus accumbens or ventral tegmental area.
    Alcohol (Fayetteville, N.Y.), 2003, Volume: 29, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Central Nervous System Depressants; Dopam

2003
Mechanisms of the influences of the central administration of substance P on ethanol consumption in chronically alcoholic rats.
    Neuroscience and behavioral physiology, 2003, Volume: 33, Issue:9

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Dopamine; Ethanol; Homovanill

2003
Central angiotensin II controls alcohol consumption via its AT1 receptor.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:11

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Angiotensin II; Angiotensin II Type 1 Receptor Blo

2005
Individual differences in ethanol self-administration following withdrawal are associated with asymmetric changes in dopamine and serotonin in the medial prefrontal cortex and amygdala.
    Alcoholism, clinical and experimental research, 2006, Volume: 30, Issue:10

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Amygdala; Animals; Behavior, Animal; Central Nervo

2006
Dopamine release in the nucleus accumbens (shell) of two lines of rats selectively bred to prefer or avoid ethanol.
    European journal of pharmacology, 2007, Nov-14, Volume: 573, Issue:1-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Anesthesia, Inhalation; Animals; Breed

2007
Effect of ethanol on extracellular dopamine in the nucleus accumbens of alcohol-preferring AA and alcohol-avoiding ANA rats.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Central Nervous System Depressants; Chrom

1995
5-HT, dopamine, norepinephrine, and related metabolites in brain of low alcohol drinking (LAD) rats shift after chronic intra-hippocampal infusion of harman.
    Neurochemical research, 1995, Volume: 20, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Brain; Chromatography, High Pressure Liqu

1995
Sex differences in mesolimbic dopamine responses to ethanol and relationship to ethanol intake in rats.
    Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism, 1995, Volume: 12

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Arousal; Corpus Striatum; Dos

1995
Sex differences in ethanol-induced dopamine release in nucleus accumbens and in ethanol consumption in rats.
    Alcoholism, clinical and experimental research, 1993, Volume: 17, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Appetitive Behavior; Corpus Striatum; Dop

1993
Selective destruction of midbrain raphe nuclei by 5,7-DHT: is brain 5-HT involved in alcohol drinking in Sprague-Dawley rats?
    Brain research, 1995, Sep-25, Volume: 693, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Alcohol Drinking; Animals; Brain Chemistry;

1995
Effects of chronic ethanol consumption and aging on dopamine, serotonin, and metabolites.
    Journal of neurochemistry, 1996, Volume: 66, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Alcohol Drinking; Animals; Brain; Dopamine; Hydroxyindoleacet

1996
Genetically determined influences on voluntary ethanol consumption: extracellular levels of ethanol and monoamines in the nucleus accumbens of the alcohol preferring AA and alcohol avoiding ANA rat lines.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1994, Volume: 2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Biogenic Monoamines; Dopamine; Ethanol; E

1994
Voluntary alcohol drinking selectively accelerates dopamine release in the ventral striatum as reflected by 3-methoxytyramine levels.
    Brain research, 1997, Nov-07, Volume: 774, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Corpus Striatum; Dopamine; Drinking; Homo

1997
Treating neonatal rats with 6-hydroxydopamine induced an increase in voluntary alcohol consumption.
    Alcoholism, clinical and experimental research, 1999, Volume: 23, Issue:4 Suppl

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Animals, Newborn; Biogenic Monoamines; Br

1999
Effects of repeated morphine on cerebral dopamine release and metabolism in AA and ANA rats.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Analgesics, Opioid; Animals; Caudate Nucleus; Dopa

2000
Biogenic aldehyde(s) derived from the action of monoamine oxidase may mediate the antidipsotropic effect of daidzin.
    Chemico-biological interactions, 2001, Jan-30, Volume: 130-132, Issue:1-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Deterrents; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehy

2001
Ethanol and delta-sleep-inducing peptide: effects on brain monoamines.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Biogenic Monoamines; Brain Chemistry; Chr

1992
Temporal studies of the inhibition of voluntary ethanol intake in the rat induced by intermittent ethanol treatment and some long term neurochemical consequences.
    Drug and alcohol dependence, 1991, Volume: 28, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Brain; Brain Mapping; Dopamin

1991
Neuroanatomic and neurochemical abnormalities in nonhuman primate infants exposed to weekly doses of ethanol during gestation.
    Alcoholism, clinical and experimental research, 1990, Volume: 14, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Brain; Corpus Striatum; Ethanol; Eye; Fem

1990
Alcohol-preferring rats: genetic sensitivity to alcohol-induced stimulation of dopamine metabolism.
    Physiology & behavior, 1990, Volume: 47, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Arousal; Brain Mapping; Caudate Nucleus;

1990
Voluntary alcohol drinking increases brain dopamine metabolism in rats.
    Annali dell'Istituto superiore di sanita, 1990, Volume: 26, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Brain Chemistry; Dopamine; Ethanol; Homov

1990
Alcohol preference and regional brain monoamine contents of N/Nih heterogeneous stock rats.
    Alcohol and drug research, 1987, Volume: 7, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Biogenic Amines; Brain Chemistry; Dopamin

1987
Contents of monoamines in forebrain regions of alcohol-preferring (P) and -nonpreferring (NP) lines of rats.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Biogenic Amines; Brain; Cereb

1987
Role of brain monoaminergic systems in the increased ethanol drinking caused by REM-sleep deprivation.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1987, Volume: 1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Brain Chemistry; Catecholamines; Citalopr

1987
Neonatal antidepressant administration suppresses concurrent active (REM) sleep and increases adult alcohol consumption in rats.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1987, Volume: 1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Animals, Newborn; Brain Chemistry; Desipr

1987
Effect of spontaneous ingestion of ethanol on brain dopamine metabolism.
    Life sciences, 1989, Volume: 44, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Brain; Caudate Nucleus; Dopamine; Ethanol

1989