3,4-dihydroxyphenylacetic acid has been researched along with Alcohol Abuse in 23 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Altogether, this indicates that semaglutide reduces alcohol drinking behaviours, possibly via a reduction in alcohol-induced reward and NAc dependent mechanisms." | 4.31 | Semaglutide reduces alcohol intake and relapse-like drinking in male and female rats. ( Aranäs, C; Blid Sköldheden, S; Edvardsson, CE; Jerlhag, E; Shevchouk, OT; Tufvesson-Alm, M; Vallöf, D; Witley, S; Zentveld, L; Zhang, Q, 2023) |
| " After chronic alcoholism, there was a decrease in the ratio of dihydroxyphenylacetic acid (DOPA) and homovanillic acid (HVA) to dopamine in the nucleus accumbens and striatum in rats subjected to alcoholism, as compared with intact controls." | 3.72 | Mechanisms of the influences of the central administration of substance P on ethanol consumption in chronically alcoholic rats. ( Bychkov, ER; Dambinova, SA; Lebedev, AA; Nikolaev, SV, 2003) |
| " There were significant, negative correlations between interview-derived lifetime aggression scores and cerebrospinal fluid concentrations of both the serotonin metabolite 5-hydroxyindoleacetic acid and the dopamine metabolite homovanillic acid." | 3.68 | Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls. ( Adinoff, B; Goldman, D; Lamparski, D; Limson, R; Linnoila, M; Ravitz, B; Roy, A, 1991) |
| " Dose-response curves for DA and 5-HT release indicated no marked difference in the sensitivity to ethanol between the lines." | 1.28 | Ethanol enhances the release of dopamine and serotonin in the nucleus accumbens of HAD and LAD lines of rats. ( Li, TK; Lumeng, L; McBride, WJ; Yoshimoto, K, 1992) |
| "The dose-response curve for morphine-induced stimulation of striatal dopamine metabolism was shifted to the right in mice which had been withdrawn for 24 hours after chronic consumption of an ethanol-containing liquid diet." | 1.26 | Alterations in opiate receptor function after chronic ethanol exposure. ( Hoffman, PL; Tabakoff, B; Urwyler, S, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (17.39) | 18.7374 |
| 1990's | 12 (52.17) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Aranäs, C | 1 |
| Edvardsson, CE | 1 |
| Shevchouk, OT | 1 |
| Zhang, Q | 1 |
| Witley, S | 1 |
| Blid Sköldheden, S | 1 |
| Zentveld, L | 1 |
| Vallöf, D | 1 |
| Tufvesson-Alm, M | 1 |
| Jerlhag, E | 1 |
| Hirth, N | 1 |
| Meinhardt, MW | 1 |
| Noori, HR | 1 |
| Salgado, H | 1 |
| Torres-Ramirez, O | 1 |
| Uhrig, S | 1 |
| Broccoli, L | 1 |
| Vengeliene, V | 1 |
| Roßmanith, M | 1 |
| Perreau-Lenz, S | 1 |
| Köhr, G | 1 |
| Sommer, WH | 1 |
| Spanagel, R | 1 |
| Hansson, AC | 1 |
| Ward, RJ | 1 |
| Colivicchi, MA | 1 |
| Allen, R | 1 |
| Schol, F | 1 |
| Lallemand, F | 1 |
| de Witte, P | 1 |
| Ballini, C | 1 |
| Corte, LD | 1 |
| Dexter, D | 1 |
| Nikolaev, SV | 2 |
| Bychkov, ER | 2 |
| Lebedev, AA | 2 |
| Dambinova, SA | 2 |
| Ojanen, S | 1 |
| Koistinen, M | 1 |
| Bäckström, P | 1 |
| Kankaanpää, A | 1 |
| Tuomainen, P | 1 |
| Hyytiä, P | 1 |
| Kiianmaa, K | 1 |
| Quintanilla, ME | 1 |
| Bustamante, D | 1 |
| Tampier, L | 1 |
| Israel, Y | 1 |
| Herrera-Marschitz, M | 1 |
| Murphy, JM | 2 |
| McBride, WJ | 3 |
| Lumeng, L | 3 |
| Li, TK | 3 |
| Hoffman, PL | 2 |
| Urwyler, S | 1 |
| Tabakoff, B | 1 |
| Barbaccia, ML | 1 |
| Bosio, A | 1 |
| Lucchi, L | 1 |
| Spano, PF | 1 |
| Trabucchi, M | 1 |
| Blanchard, BA | 1 |
| Glick, SD | 1 |
| Hegarty, AA | 1 |
| Vogel, WH | 1 |
| Philpot, RM | 1 |
| Kirstein, CL | 1 |
| Anokhina, IP | 1 |
| Vertinskaia, AG | 1 |
| Vekshina, NL | 1 |
| Nebarakova, TP | 1 |
| Ovchinnikov, IV | 1 |
| Druzhina, EV | 1 |
| Ovchinnikova, OI | 1 |
| Diana, M | 2 |
| Gessa, GL | 3 |
| Rossetti, ZL | 2 |
| Yoshimoto, K | 1 |
| Pellegrino, SM | 1 |
| Druse, MJ | 1 |
| Melis, F | 1 |
| Carboni, S | 1 |
| Limson, R | 1 |
| Goldman, D | 1 |
| Roy, A | 1 |
| Lamparski, D | 1 |
| Ravitz, B | 1 |
| Adinoff, B | 1 |
| Linnoila, M | 1 |
| Wahlström, G | 1 |
| Magnusson, O | 1 |
| Nordberg, A | 1 |
| Stenström, A | 1 |
| Tiger, G | 1 |
| Fadda, F | 1 |
| Colombo, G | 1 |
| Eisenhofer, G | 1 |
| Szabo, G | 1 |
23 other studies available for 3,4-dihydroxyphenylacetic acid and Alcohol Abuse
| Article | Year |
|---|---|
Semaglutide reduces alcohol intake and relapse-like drinking in male and female rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Dopamine; Ethanol; Exenatide; | 2023 |
Convergent evidence from alcohol-dependent humans and rats for a hyperdopaminergic state in protracted abstinence.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Alcohol Abstinence; Alcoholism; Animals; Benzazepines; | 2016 |
Neuro-inflammation induced in the hippocampus of 'binge drinking' rats may be mediated by elevated extracellular glutamate content.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Amino Acids; Animals; Biogenic Monoamines; Conditioning, | 2009 |
[The influence of substance P central administration on ethanol intake in rats chronically exposed to alcohol].
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Corpus Striatum; Dopamine; Dr | 2002 |
Differential behavioural sensitization to intermittent morphine treatment in alcohol-preferring AA and alcohol-avoiding ANA rats: role of mesolimbic dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Chromatography, High Pressure Liquid; Dopamine; | 2003 |
Mechanisms of the influences of the central administration of substance P on ethanol consumption in chronically alcoholic rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Dopamine; Ethanol; Homovanill | 2003 |
Dopamine release in the nucleus accumbens (shell) of two lines of rats selectively bred to prefer or avoid ethanol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Anesthesia, Inhalation; Animals; Breed | 2007 |
Monoamine and metabolite levels in CNS regions of the P line of alcohol-preferring rats after acute and chronic ethanol treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholic Intoxication; Alcoholism; Animals; Brain Chemistry; Choice | 1983 |
Alterations in opiate receptor function after chronic ethanol exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Caudate Nucleus; Corpus Striatum; Dihydromorphi | 1982 |
Neuronal mechanisms regulating ethanol effects on the dopaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Dopamine; Ethanol; Haloperidol; Humans; Male; M | 1982 |
Sex differences in mesolimbic dopamine responses to ethanol and relationship to ethanol intake in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Arousal; Corpus Striatum; Dos | 1995 |
Modulation of the stress response by ethanol in the rat frontal cortex.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Cerebral Cortex; Dopamine; Dose-Response Relati | 1993 |
The effects of repeated alcohol exposure on the neurochemistry of the periadolescent nucleus accumbens septi.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Alcoholism; Animals; Dopamine; Dose-Response Relationship, Dr | 1998 |
[Hereditary alcoholism: some neurochemical and genetic mechanisms].
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Alleles; Brain; Dihydroxyphenylalanine; DNA; Genetic Dis | 1999 |
Lack of tolerance to ethanol-induced stimulation of mesolimbic dopamine system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholic Intoxication; Alcoholism; Animals; Corpus Striatum; Dopami | 1992 |
Ethanol enhances the release of dopamine and serotonin in the nucleus accumbens of HAD and LAD lines of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Dopamine; Dose-Response Relationship, Drug; Eth | 1992 |
The effects of chronic ethanol consumption on the mesolimbic and nigrostriatal dopamine systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Benzazepines; Brain Mapping; Corpus Striatum; D | 1992 |
Alcohol withdrawal in rats is associated with a marked fall in extraneuronal dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Withdrawal Delirium; Alcoholism; Animals; Corpus Striatum; D | 1992 |
Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aggression; Alcoholism; Homovanillic Acid; Humans; Hydroxyind | 1991 |
Temporal studies of the inhibition of voluntary ethanol intake in the rat induced by intermittent ethanol treatment and some long term neurochemical consequences.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Brain; Brain Mapping; Dopamin | 1991 |
Genetic sensitivity to effect of ethanol on dopaminergic system in alcohol preferring rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Brain; Caudate Nucleus; Dopamine; Ethanol; Fron | 1991 |
Opposite changes in turnover of noradrenaline and dopamine in the CNS of ethanol-dependent mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcoholism; Animals; Brain; Catecholamines; Dopamine; Heart; Male; M | 1990 |
Contents of monoamines in forebrain regions of alcohol-preferring (P) and -nonpreferring (NP) lines of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Biogenic Amines; Brain; Cereb | 1987 |