3,4-dihydroxyphenylacetic acid has been researched along with Aging in 164 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Excerpt | Relevance | Reference |
---|---|---|
"Haloperidol treatment (2 hours) accelerated striatal DA turnover similarly in all age groups, by about 100%." | 5.26 | Aging and haloperidol-induced dopamine turnover in the nigro-striatal pathway of C57BL/6J mice. ( Finch, CE; Osterburg, HH; Severson, JA, 1981) |
"Children whose mothers used cocaine during pregnancy appear to have an increased incidence of certain neurobehavioral deficits." | 3.71 | Prenatal cocaine exposure increases mesoprefrontal dopamine neuron responsivity to mild stress. ( Elsworth, JD; Morrow, BA; Roth, RH, 2001) |
"The aging of the cochlear dopaminergic system has been analyzed by quantifying the levels of dopamine (DA) and its metabolites (3,4-dihydroxyphenylacetic acid, DOPAC, and homovanillic acid, HVA) in adult rats aged 3, 12 or 24 months." | 3.71 | Effects of aging on cochlear monoamine turnover. ( Dávila, D; Gil-Loyzaga, P; Muñoz, E; Vicente-Torres, MA, 2002) |
"Taurine is present in high concentration in the mammalian brain and is known to decline with aging." | 3.70 | An age-related decline in striatal taurine is correlated with a loss of dopaminergic markers. ( Cullen, MJ; Dawson, R; Gollub, M; Liu, S; Pelleymounter, MA, 1999) |
" In addition, the exposure to new environmental condition elevated blood corticosterone levels and enhanced behavioral activities to a greater extent in the Dex group than in controls at 7 wk of life, suggesting that elevated glucocorticoid levels during the pregnancy mimicked prenatal mild stress, producing developmental alterations in brain monoamine metabolism, endocrine response, and behavior in adult offspring." | 3.69 | Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring. ( Kamei, K; Kitera, K; Mikuni, M; Muneoka, K; Ogawa, T; Takahashi, K; Takigawa, M, 1997) |
" The results indicate that aging did not significantly alter the levels of norepinephrine (NE), dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) in frontal (FCX), parietal (PCX) and occipital cortices (OCX)." | 3.68 | Effect of aging and diet restriction on monoamines and amino acids in cerebral cortex of Fischer-344 rats. ( Friedman, E; Yeung, JM, 1991) |
"The long-term effect of the parkinsonism-inducing neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on central monoaminergic neurons in young (2-3 months) and aging (12 months) C57BL/6 mice has been studied using neurochemical and immunocytochemical techniques." | 3.68 | Long-term effect of MPTP in the mouse brain in relation to aging: neurochemical and immunocytochemical analysis. ( Date, I; Felten, DL; Felten, SY, 1990) |
" Neither cortical NE nor its metabolite methoxyhydroxyphenylglycol sulphate (MHPG-SO4) were significantly changed by aging." | 3.67 | Effect of aging on monoamines and their metabolites in the rat brain. ( Carfagna, N; Moretti, A; Trunzo, F, 1987) |
"Levodopa (l-DOPA, l-3,4-dihydroxyphenylalanine) is the most effective drug in the symptomatic treatment of Parkinson's disease (PD), but chronic use initiates a maladaptive process leading to l-DOPA-induced dyskinesia (LID)." | 1.46 | Cerebrospinal fluid levels of catecholamines and its metabolites in Parkinson's disease: effect of l-DOPA treatment and changes in levodopa-induced dyskinesia. ( Andersen, AD; Binzer, M; Blaabjerg, M; Gramsbergen, JBP; Kamal, A; Kjaer, TW; Stenager, E; Thagesen, H, 2017) |
"Idiopathic Parkinson's disease (PD) is a neurodegenerative disorder of mature and older individuals." | 1.36 | Modeling a sensitization stage and a precipitation stage for Parkinson's disease using prenatal and postnatal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration. ( Charlton, CG; King, J; Mackey, V; Muthian, G, 2010) |
" Although increasing the dosage of d-METH (20 to 80 mg/kg) did increase the GFAP response (100% over control), it was still well below that usually exhibited at the usual neurotoxic dosage (300-400% over control) in fully mature mice." | 1.31 | Age as a susceptibility factor in the striatal dopaminergic neurotoxicity observed in the mouse following substituted amphetamine exposure. ( Ali, SF; Miller, DB; O'Callaghan, JP, 2000) |
" A treatment history of high AMPH dosage was associated with a marked sensitization of the exploratory behavior in adults, whereas it induced a quite opposite profile in periadolescents." | 1.31 | Striatal dopamine sensitization to D-amphetamine in periadolescent but not in adult rats. ( Laviola, G; Pascucci, T; Pieretti, S, 2001) |
"The Fragile X syndrome, a common form of mental retardation in humans, is caused by silencing the fragile X mental retardation (FMR1) gene leading to the absence of the encoded fragile X mental retardation protein 1 (FMRP)." | 1.31 | Alterations of amino acids and monoamine metabolism in male Fmr1 knockout mice: a putative animal model of the human fragile X mental retardation syndrome. ( Braun, K; Gruss, M, 2001) |
"Nomifensine treatment significantly increased TH enzyme amount in substantia nigra (39." | 1.30 | Chronic inhibition of the high-affinity dopamine uptake system increases oxidative damage to proteins in the aged rat substantia nigra. ( Cano, J; Machado, A; Rodríguez-Gómez, JA; Romero-Ramos, M; Venero, JL, 1997) |
"Sodium azide is an inhibitor of cytochrome oxidase which produces selective striatal lesions in both rodents and primates." | 1.29 | Systemic or local administration of azide produces striatal lesions by an energy impairment-induced excitotoxic mechanism. ( Beal, MF; Brouillet, E; Henshaw, DR; Hyman, BT; Jenkins, BG; Rosen, BR; Schulz, JB; Sodhi, P, 1994) |
" These results suggest that SAM rapidly undergoes neurochemical changes which are considered to be part of the normal aging process, and these changes were attenuated by chronic administration of nimodipine." | 1.29 | Neurochemical changes related to ageing in the senescence-accelerated mouse brain and the effect of chronic administration of nimodipine. ( Kabuto, H; Mori, A; Murakami, M; Sawada, S; Yokoi, I, 1995) |
" Reducing the ET to 4 degrees C during dosing decreased the peak and average DA levels attained during the 4 x 5 mg/kg METH administration to about 50% of that observed at a 23 degrees C ET." | 1.29 | Effects of a cold environment or age on methamphetamine-induced dopamine release in the caudate putamen of female rats. ( Bowyer, JF; Gough, B; Holson, RR; Lipe, GW; Newport, GD; Slikker, W, 1993) |
" Eighteen-day-old rats were 35% and 63% more sensitive than adults to the effects of haloperidol on striatal and accumbens turnover and had steeper dose-response curves." | 1.29 | Developmental differences in acute nigrostriatal and mesocorticolimbic system response to haloperidol. ( Baldessarini, RJ; Barber, NI; Campbell, A; Gallitano, AL; Gelbard, HA; Marsh, E; Teicher, MH, 1993) |
" A dose-response effect of apomorphine on extracellular dopamine was observed in all age groups except at 10-11 days of age." | 1.29 | The ontogeny of apomorphine-induced alterations of neostriatal dopamine release: effects on spontaneous release. ( Andersen, SL; Gazzara, RA, 1993) |
" Part 1 of the study established a dose-response curve and the temporal pattern of GSH loss and recovery in the substantia nigra and striatum following acute BSO treatment." | 1.29 | Effect of buthionine sulfoximine, a synthesis inhibitor of the antioxidant glutathione, on the murine nigrostriatal neurons. ( Andersen, JK; Hamill, RW; Harnish, P; Hom, DG; Lee, FY; McNeill, TH; Mo, JQ, 1996) |
"Biogenic amines in pons and striatum have been dosed in twenty-four months old Wistar male rats." | 1.27 | [Biochemical changes in 24-month-old Wistar rats]. ( Della Zuana, O; Duhault, J; Lonchampt, M; Roman, F; Saint Romas, G, 1984) |
" Two different dosage schedules of MPTP, i." | 1.27 | Long-term effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal dopamine content in young and mature mice. ( Mizuno, Y; Niijima, K; Saitoh, T, 1987) |
"Haloperidol treatment (2 hours) accelerated striatal DA turnover similarly in all age groups, by about 100%." | 1.26 | Aging and haloperidol-induced dopamine turnover in the nigro-striatal pathway of C57BL/6J mice. ( Finch, CE; Osterburg, HH; Severson, JA, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 30 (18.29) | 18.7374 |
1990's | 82 (50.00) | 18.2507 |
2000's | 37 (22.56) | 29.6817 |
2010's | 15 (9.15) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Li, Y | 1 |
Sun, Y | 1 |
Yang, J | 1 |
Wu, Y | 1 |
Yu, J | 1 |
Li, B | 1 |
Mora-Gallegos, A | 1 |
Rojas-Carvajal, M | 1 |
Salas, S | 1 |
Saborío-Arce, A | 1 |
Fornaguera-Trías, J | 1 |
Brenes, JC | 1 |
Didriksen, M | 1 |
Fejgin, K | 1 |
Nilsson, SR | 1 |
Birknow, MR | 1 |
Grayton, HM | 1 |
Larsen, PH | 1 |
Lauridsen, JB | 1 |
Nielsen, V | 1 |
Celada, P | 1 |
Santana, N | 1 |
Kallunki, P | 1 |
Christensen, KV | 1 |
Werge, TM | 1 |
Stensbøl, TB | 1 |
Egebjerg, J | 1 |
Gastambide, F | 1 |
Artigas, F | 1 |
Bastlund, JF | 1 |
Nielsen, J | 1 |
Bergen, MA | 1 |
Park, HN | 1 |
Chakraborty, R | 1 |
Landis, EG | 1 |
Sidhu, C | 1 |
He, L | 1 |
Iuvone, PM | 2 |
Pardue, MT | 1 |
Andersen, AD | 1 |
Blaabjerg, M | 1 |
Binzer, M | 1 |
Kamal, A | 1 |
Thagesen, H | 1 |
Kjaer, TW | 1 |
Stenager, E | 1 |
Gramsbergen, JBP | 1 |
Minematsu, M | 1 |
Nakajima, K | 1 |
Topic, B | 1 |
Oitzl, MS | 1 |
Meijer, OC | 1 |
Huston, JP | 1 |
de Souza Silva, MA | 1 |
Ling, Z | 1 |
Zhu, Y | 1 |
Tong, CW | 1 |
Snyder, JA | 1 |
Lipton, JW | 1 |
Carvey, PM | 1 |
Natividad, LA | 1 |
Tejeda, HA | 1 |
Torres, OV | 1 |
O'Dell, LE | 1 |
Dluzen, DE | 4 |
Ji, J | 1 |
McDermott, JL | 4 |
Heermann, S | 1 |
Opazo, F | 1 |
Falkenburger, B | 1 |
Krieglstein, K | 1 |
Spittau, B | 1 |
Li, CR | 1 |
Huang, GB | 1 |
Sui, ZY | 1 |
Han, EH | 1 |
Chung, YC | 1 |
Muthian, G | 1 |
Mackey, V | 1 |
King, J | 1 |
Charlton, CG | 1 |
Oyama, G | 1 |
Yoshimi, K | 1 |
Natori, S | 1 |
Chikaoka, Y | 1 |
Ren, YR | 1 |
Funayama, M | 1 |
Shimo, Y | 1 |
Takahashi, R | 1 |
Nakazato, T | 1 |
Kitazawa, S | 1 |
Hattori, N | 1 |
Allen, E | 1 |
Carlson, KM | 1 |
Zigmond, MJ | 2 |
Cavanaugh, JE | 1 |
Schumm, S | 1 |
Sebban, C | 1 |
Cohen-Salmon, C | 2 |
Callebert, J | 1 |
Launay, JM | 2 |
Golmard, JL | 1 |
Boussicault, L | 1 |
Petropoulos, I | 1 |
Hild, A | 1 |
Rousselet, E | 1 |
Prigent, A | 1 |
Friguet, B | 1 |
Mariani, J | 1 |
Hirsch, EC | 1 |
Wu, G | 1 |
Lu, ZH | 1 |
Kulkarni, N | 1 |
Ledeen, RW | 1 |
Pruett, BS | 1 |
Salvatore, MF | 1 |
Miura, H | 1 |
Qiao, H | 1 |
Ohta, T | 1 |
Stanford, JA | 3 |
Vorontsova, E | 1 |
Surgener, SP | 1 |
Gerhardt, GA | 5 |
Fowler, SC | 1 |
Purdom, MS | 2 |
Currier, TD | 1 |
Dietz, DM | 1 |
Pletnikov, MV | 1 |
Alquicer, G | 1 |
Silva-Gómez, AB | 1 |
Peralta, F | 1 |
Flores, G | 1 |
Pardon, MC | 1 |
Hanoun, N | 1 |
Perez-Diaz, F | 1 |
Joubert, C | 1 |
Christen, Y | 1 |
Hamon, M | 1 |
Saito, S | 1 |
Takagi, T | 1 |
Koutoku, T | 1 |
Saito, ES | 1 |
Hirakawa, H | 1 |
Tomonaga, S | 1 |
Tachibana, T | 1 |
Denbow, DM | 1 |
Furuse, M | 1 |
Segovia, G | 1 |
Mora, F | 1 |
Götz, ME | 1 |
Malz, CR | 1 |
Dirr, A | 1 |
Blum, D | 1 |
Gsell, W | 1 |
Schmidt, S | 1 |
Burger, R | 1 |
Pohli, S | 1 |
Riederer, P | 1 |
Boyce, PJ | 1 |
Finlay, JM | 1 |
Chanut, E | 1 |
Labarthe, B | 1 |
Lacroix, B | 1 |
Noda, A | 1 |
Gasdeblay, S | 1 |
Bondier, JR | 1 |
Versaux-Botteri, C | 1 |
Hamaue, N | 1 |
Ogata, A | 1 |
Terado, M | 1 |
Ohno, K | 1 |
Kikuchi, S | 1 |
Sasaki, H | 1 |
Tashiro, K | 1 |
Hirafuji, M | 1 |
Minami, M | 1 |
Villégier, AS | 1 |
Lotfipour, S | 1 |
McQuown, SC | 1 |
Belluzzi, JD | 1 |
Leslie, FM | 1 |
Sawada, H | 1 |
Hishida, R | 1 |
Hirata, Y | 1 |
Ono, K | 1 |
Suzuki, H | 1 |
Muramatsu, S | 1 |
Nakano, I | 1 |
Nagatsu, T | 1 |
Sawada, M | 1 |
Roman, F | 1 |
Della Zuana, O | 1 |
Lonchampt, M | 1 |
Saint Romas, G | 1 |
Duhault, J | 1 |
Simpkins, JW | 1 |
Lasley, SM | 1 |
Greenland, RD | 1 |
Minnema, DJ | 1 |
Michaelson, IA | 1 |
Ponzio, F | 1 |
Calderini, G | 2 |
Lomuscio, G | 1 |
Vantini, G | 1 |
Toffano, G | 3 |
Algeri, S | 1 |
Yoshino, K | 1 |
Riccardi, F | 1 |
Covelli, V | 1 |
Spano, PF | 2 |
Govoni, S | 2 |
Trabucchi, M | 3 |
Montefusco, O | 1 |
Missale, C | 1 |
Rozzini, R | 1 |
Osterburg, HH | 3 |
Donahue, HG | 1 |
Severson, JA | 2 |
Finch, CE | 3 |
Roth, BL | 1 |
Galloway, MP | 1 |
Coscia, CJ | 1 |
Memo, M | 1 |
Lucchi, L | 1 |
Venero, JL | 5 |
de la Roza, C | 1 |
Machado, A | 9 |
Cano, J | 9 |
Henderson, MG | 1 |
McMillen, BA | 1 |
Jinnah, HA | 1 |
Wojcik, BE | 1 |
Hunt, M | 1 |
Narang, N | 1 |
Lee, KY | 1 |
Goldstein, M | 1 |
Wamsley, JK | 1 |
Langlais, PJ | 1 |
Friedmann, T | 1 |
Brouillet, E | 1 |
Hyman, BT | 1 |
Jenkins, BG | 1 |
Henshaw, DR | 1 |
Schulz, JB | 1 |
Sodhi, P | 1 |
Rosen, BR | 1 |
Beal, MF | 1 |
Irwin, I | 1 |
DeLanney, LE | 1 |
McNeill, T | 1 |
Chan, P | 1 |
Forno, LS | 1 |
Murphy, GM | 1 |
Di Monte, DA | 1 |
Sandy, MS | 1 |
Langston, JW | 1 |
Gupta, M | 1 |
Wiener, HL | 1 |
Kabuto, H | 1 |
Yokoi, I | 1 |
Mori, A | 1 |
Murakami, M | 1 |
Sawada, S | 1 |
Armando, I | 1 |
Nowicki, S | 1 |
Aguirre, J | 1 |
Barontini, M | 1 |
Erdtsieck-Ernste, EB | 1 |
Feenstra, MG | 1 |
Botterblom, M | 1 |
Boer, GJ | 1 |
Ali, SF | 6 |
Holson, RR | 2 |
Newport, GD | 3 |
Slikker, W | 3 |
Bowyer, JF | 2 |
Gilad, GM | 1 |
Li, R | 1 |
Wyatt, RJ | 1 |
Tizabi, Y | 1 |
Santiago, M | 4 |
Crawford, CA | 1 |
McDougall, SA | 1 |
Bardo, MT | 1 |
David, SN | 1 |
Cadet, JL | 1 |
Navarro, M | 1 |
Rodríguez de Fonseca, F | 1 |
Hernández, ML | 2 |
Ramos, JA | 3 |
Fernández-Ruiz, JJ | 2 |
Tsai, YF | 1 |
Tsai, HW | 1 |
Tai, MY | 1 |
Budygin, EA | 1 |
Kovalev, GI | 1 |
Gaĭntdinov, RR | 1 |
Kudrin, VS | 2 |
Voronina, TA | 1 |
Stewart, J | 1 |
Rajabi, H | 1 |
Gough, B | 1 |
Lipe, GW | 1 |
Tsuchida, K | 1 |
Ujike, H | 1 |
Kanzaki, A | 1 |
Fujiwara, Y | 1 |
Akiyama, K | 1 |
Joseph, SA | 1 |
Walker, DW | 1 |
Gazzara, RA | 2 |
Andersen, SL | 2 |
Teicher, MH | 1 |
Barber, NI | 1 |
Gelbard, HA | 1 |
Gallitano, AL | 1 |
Campbell, A | 1 |
Marsh, E | 1 |
Baldessarini, RJ | 1 |
Desole, MS | 1 |
Esposito, G | 1 |
Enrico, P | 1 |
Miele, M | 1 |
Fresu, L | 1 |
De Natale, G | 1 |
Miele, E | 1 |
Grella, G | 1 |
Afonso, D | 2 |
Santana, C | 2 |
Rodriguez, M | 2 |
Yao, H | 1 |
Nagao, T | 1 |
Ooboshi, H | 1 |
Matsumoto, T | 1 |
Hirano, M | 1 |
Nakahara, T | 1 |
Sadoshima, S | 1 |
Uchimura, H | 1 |
Fujishima, M | 1 |
Rose, S | 2 |
Nomoto, M | 1 |
Jackson, EA | 1 |
Gibb, WR | 1 |
Jaehnig, P | 1 |
Jenner, P | 2 |
Marsden, CD | 2 |
Jensen, EW | 1 |
Eldrup, E | 2 |
Kelbaek, H | 1 |
Nielsen, SL | 1 |
Christensen, NJ | 2 |
Cabib, S | 1 |
Puglisi-Allegra, S | 1 |
D'Amato, FR | 1 |
Hastings, JA | 3 |
Pavia, JM | 2 |
Morris, MJ | 3 |
Woods, JM | 1 |
Druse, MJ | 1 |
Nakano, M | 1 |
Mizuno, T | 1 |
Andersen, JK | 1 |
Mo, JQ | 1 |
Hom, DG | 1 |
Lee, FY | 1 |
Harnish, P | 1 |
Hamill, RW | 1 |
McNeill, TH | 1 |
Ueda, Y | 1 |
Komatsu, M | 1 |
Hiramatsu, M | 1 |
Cransac, H | 1 |
Peyrin, L | 2 |
Cottet-Emard, JM | 1 |
Farhat, F | 1 |
Pequignot, JM | 1 |
Reber, A | 1 |
Bonnin, A | 1 |
de Miguel, R | 2 |
Castro, JG | 1 |
Penit-Soria, J | 1 |
Durand, C | 1 |
Herve, D | 1 |
Besson, MJ | 1 |
Schneider, JS | 2 |
Romero-Ramos, M | 1 |
Rodríguez-Gómez, JA | 1 |
Sajnani, GG | 1 |
Abreu, P | 1 |
Castro, R | 1 |
Muneoka, K | 1 |
Mikuni, M | 1 |
Ogawa, T | 1 |
Kitera, K | 1 |
Kamei, K | 1 |
Takigawa, M | 1 |
Takahashi, K | 1 |
McClure-Sharp, JM | 1 |
Hebert, MA | 1 |
Philpot, RM | 2 |
Kirstein, CL | 2 |
Schneider, ML | 1 |
Clarke, AS | 1 |
Kraemer, GW | 2 |
Roughton, EC | 1 |
Lubach, GR | 1 |
Rimm-Kaufman, S | 1 |
Schmidt, D | 1 |
Ebert, M | 1 |
Míguez, JM | 1 |
Recio, J | 1 |
Sánchez-Barceló, E | 1 |
Aldegunde, M | 1 |
Lemierre, S | 1 |
Rouch, C | 1 |
Nicolaidis, S | 1 |
Orosco, M | 1 |
Maloney, RE | 1 |
Dawson, R | 1 |
Pelleymounter, MA | 1 |
Cullen, MJ | 1 |
Gollub, M | 1 |
Liu, S | 1 |
Kucherianu, VG | 1 |
Kryzhanovskiĭ, GN | 1 |
Iurasov, VV | 1 |
Nikushkin, EV | 1 |
Zhigal'tsev, IV | 1 |
Goettl, VM | 1 |
Wemlinger, TA | 1 |
Duchemin, AM | 1 |
Neff, NH | 1 |
Hadjiconstantinou, M | 1 |
Vieira-Coelho, MA | 1 |
Hussain, T | 1 |
Kansra, V | 1 |
Serrao, MP | 1 |
Guimaraes, JT | 1 |
Pestana, M | 2 |
Soares-Da-Silva, P | 4 |
Lokhandwala, MF | 1 |
Ueda, S | 1 |
Aikawa, M | 1 |
Ishizuya-Oka, A | 1 |
Yamaoka, S | 1 |
Koibuchi, N | 1 |
Yoshimoto, K | 1 |
Shui, H | 1 |
Peng, Y | 1 |
Wu, R | 1 |
Tsai, Y | 1 |
Miller, DB | 1 |
O'Callaghan, JP | 1 |
Mandavilli, BS | 1 |
Van Houten, B | 1 |
MohanKumar, PS | 1 |
MohanKumar, SM | 1 |
Quadri, SK | 1 |
Voogt, JL | 1 |
Lee, JJ | 1 |
Chang, CK | 1 |
Liu, IM | 1 |
Chi, TC | 1 |
Yu, HJ | 1 |
Cheng, JT | 1 |
Laviola, G | 1 |
Pascucci, T | 1 |
Pieretti, S | 1 |
Fox, CM | 1 |
Gash, DM | 1 |
Smoot, MK | 1 |
Cass, WA | 1 |
Bairam, A | 1 |
Néji, H | 1 |
Kinkead, R | 1 |
Marchal, F | 1 |
Campbell, BM | 1 |
Gresch, PJ | 1 |
Walker, PD | 1 |
Ferreira, A | 1 |
Bettencourt, P | 1 |
Correia, F | 1 |
Serrão, P | 1 |
Martins, L | 1 |
Cerqueira-Gomes, M | 1 |
Imam, SZ | 1 |
Elsworth, JD | 1 |
Morrow, BA | 1 |
Roth, RH | 1 |
Vicente-Torres, MA | 2 |
Muñoz, E | 2 |
Dávila, D | 2 |
Gil-Loyzaga, P | 2 |
Gruss, M | 1 |
Braun, K | 1 |
Meyer, JS | 1 |
Summavielle, T | 1 |
Magalhães, A | 1 |
Castro-Vale, I | 1 |
de Sousa, L | 1 |
Tavares, MA | 1 |
Muskiet, FA | 1 |
Fremouw-Ottevangers, DC | 1 |
van der Meulen, J | 1 |
Wolthers, BG | 1 |
de Vries, JA | 1 |
Dalmaz, Y | 1 |
Sann, L | 1 |
Dutruge, J | 1 |
Davis, AJ | 1 |
Holzbauer, M | 1 |
Sharman, DF | 1 |
Fernandes, MH | 2 |
Fernandez-Ruiz, J | 1 |
Cebeira, M | 1 |
Pasinetti, GM | 1 |
Kelly, AB | 1 |
Kohama, S | 1 |
Morgan, DG | 1 |
Reinhard, JF | 1 |
Stellwagen, RH | 1 |
Arevalo, R | 1 |
Darney, KJ | 1 |
Goldman, JM | 1 |
Vandenbergh, JG | 1 |
Martineau, J | 1 |
Garreau, B | 1 |
Barthélémy, C | 1 |
Jouve, J | 1 |
Lelord, G | 1 |
Hadfield, MG | 1 |
Milio, C | 1 |
Castañeda, E | 1 |
Whishaw, IQ | 1 |
Lermer, L | 1 |
Robinson, TE | 1 |
Taylor, MD | 1 |
de Ceballos, ML | 1 |
Chong, PN | 1 |
Tatton, WG | 1 |
Greenwood, CE | 1 |
Salo, PT | 1 |
Seniuk, NA | 1 |
Dluzen, D | 1 |
McDermott, J | 1 |
Sato, N | 1 |
Shimizu, H | 1 |
Shimomura, Y | 1 |
Uehara, Y | 1 |
Takahashi, M | 1 |
Negishi, M | 1 |
Yeung, JM | 1 |
Friedman, E | 1 |
Hetland, ML | 1 |
Bratholm, P | 1 |
Date, I | 1 |
Felten, DL | 1 |
Felten, SY | 1 |
Giorgi, O | 2 |
Porceddu, ML | 2 |
Pepitoni, S | 1 |
Serra, GP | 1 |
Biggio, G | 2 |
Walters, DE | 1 |
Chapman, CD | 1 |
Howard, SG | 1 |
Buu, NT | 1 |
Debinski, W | 1 |
Fornstedt, B | 1 |
Pileblad, E | 1 |
Carlsson, A | 1 |
Moretti, A | 2 |
Carfagna, N | 2 |
Trunzo, F | 2 |
Bruno, JP | 1 |
Jackson, D | 1 |
Stricker, EM | 1 |
Reinoso-Suárez, F | 1 |
McKeon, TW | 1 |
Hendley, ED | 1 |
Vaughn, DM | 1 |
Smyth, GB | 1 |
Whitmer, WL | 1 |
Satjawatcharaphong, C | 1 |
Ebert, MH | 1 |
Schmidt, DE | 1 |
McKinney, WT | 1 |
Tigges, M | 1 |
Fernandes, A | 1 |
Tigges, J | 1 |
Lun, A | 1 |
Szuecz, L | 1 |
Gross, J | 1 |
Horvath, G | 1 |
Nagy, I | 1 |
De Montis, G | 1 |
Mele, S | 1 |
MacRae, PG | 1 |
Spirduso, WW | 1 |
Walters, TJ | 1 |
Farrar, RP | 1 |
Wilcox, RE | 1 |
Roizen, MF | 1 |
Koblin, DD | 1 |
Johnson, BH | 1 |
Eger, EI | 1 |
Bainton, CR | 1 |
Lurz, FW | 1 |
Saitoh, T | 1 |
Niijima, K | 1 |
Mizuno, Y | 1 |
Cousin, KM | 1 |
Gerald, MC | 1 |
Uretsky, NJ | 1 |
164 other studies available for 3,4-dihydroxyphenylacetic acid and Aging
Article | Year |
---|---|
Age-dependent dopaminergic dysfunction following fetal exposure to atrazine in SD rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Atrazine; Corpus Striatum; Dopamine; Dopamine Plasma | 2014 |
Age-dependent effects of environmental enrichment on spatial memory and neurochemistry.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Environment; gamma-Aminobutyric Acid; Glut | 2015 |
Persistent gating deficit and increased sensitivity to NMDA receptor antagonism after puberty in a new mouse model of the human 22q11.2 microdeletion syndrome: a study in male mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Auditory Perception; Corpus Striatum; DiGeorge Syndr | 2017 |
Altered Refractive Development in Mice With Reduced Levels of Retinal Dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biomarkers; Disease Models, Animal; Disease Progress | 2016 |
Cerebrospinal fluid levels of catecholamines and its metabolites in Parkinson's disease: effect of l-DOPA treatment and changes in levodopa-induced dyskinesia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Aging; Antiparkinson Agents; Catecholamines; Dopamine; | 2017 |
Significant effect of dimethylsulfoniopropionate on Parkinson's disease of senescence-accelerated mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Alzheimer Disea | 2008 |
Differential susceptibility to extinction-induced despair and age-dependent alterations in the hypothalamic-pituitary-adrenal axis and neurochemical parameters.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Behavior, Animal; Biomarkers; Depression; Dopamine; | 2008 |
Prenatal lipopolysaccharide does not accelerate progressive dopamine neuron loss in the rat as a result of normal aging.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; Analysis of Variance; Animals; Body Weight; Brai | 2009 |
Nicotine withdrawal produces a decrease in extracellular levels of dopamine in the nucleus accumbens that is lower in adolescent versus adult male rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Bicuculline; Dopamine; Extracellular Space; GABA Ant | 2010 |
Age-related changes in nigrostriatal dopaminergic function in heterozygous mutant dopamine transporter knock-out mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; Dopamine Plasma Membrane | 2010 |
Aged Tgfbeta2/Gdnf double-heterozygous mice show no morphological and functional alterations in the nigrostriatal system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Animals; Chromatography, High Pressure | 2010 |
Effects of 6-hydroxydopamine lesioning of the medial prefrontal cortex on social interactions in adolescent and adult rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Exploratory Behavior; Interpersonal Relati | 2010 |
Modeling a sensitization stage and a precipitation stage for Parkinson's disease using prenatal and postnatal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Birth | 2010 |
Impaired in vivo dopamine release in parkin knockout mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Body Weight; Corpus Striatum; Dopamine; Homovanillic | 2010 |
L-DOPA reverses motor deficits associated with normal aging in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Brain Chemistry; Dopamine; Dopamine Agents; H | 2011 |
Aging of the dopaminergic system and motor behavior in mice intoxicated with the parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; An | 2012 |
Deficiency of ganglioside GM1 correlates with Parkinson's disease in mice and humans.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aged, 80 and over; Aging; Animals; Antiparkinson Agents; Blott | 2012 |
Nigral GFRα1 infusion in aged rats increases locomotor activity, nigral tyrosine hydroxylase, and dopamine content in synchronicity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Glial Cell Line-Derived Neurotrophic Facto | 2013 |
Influence of aging and social isolation on changes in brain monoamine turnover and biosynthesis of rats elicited by novelty stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Brain; Chromatography, High Pre | 2002 |
Aged Fischer 344 rats exhibit altered locomotion in the absence of decreased locomotor activity: exacerbation by nomifensine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; Analysis of Variance; Animals; Corpus Striatum; | 2002 |
Microdialysis studies of D-amphetamine-evoked striatal dopamine overflow in young versus aged F344 rats: effects of concentration and order of administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Central Nervous System Stimulants; Chromatography, H | 2003 |
Differential effects of post-implantation time on potassium- versus D-amphetamine-evoked dopamine overflow in the striatum of F344 rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dextroamphetamine; Dopamine; Extracellular Space; Mi | 2003 |
Postnatal weight gain inhibition does not account for neurobehavioral consequences of neonatal Borna disease virus infection.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, An | 2003 |
Neonatal ventral hippocampus lesion alters the dopamine content in the limbic regions in postpubertal rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Behavior, Animal; Denervation; Dis | 2004 |
Long-term treatment with the antioxidant drug EGb 761 at senescence restored some neurobehavioral effects of chronic ultramild stress exposure seen in young mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Antioxidants; Behavior, Animal; Brain; Brain Chemist | 2004 |
Differences in catecholamine metabolism and behaviour in neonatal broiler and layer chicks.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Body Weight; Brain; Catecholamines; Chickens; Dopami | 2004 |
Dopamine and GABA increases produced by activation of glutamate receptors in the nucleus accumbens are decreased during aging.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Ana | 2005 |
Brain aging phenomena in migrating sockeye salmon Oncorhynchus nerka nerka.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animal Migration; Animals; Antioxidants; Apoptosis; Brain; Ca | 2005 |
Neonatal depletion of cortical dopamine: effects on dopamine turnover and motor behavior in juvenile and adult rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Aging; Analysis of Variance; Animals; Animals, Ne | 2005 |
Variations of dopamine, serotonin, and amino acid concentrations in Noda epileptic rat (NER) retina.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amino Acids; Animals; Animals, Newborn; Biogenic Monoamines; | 2006 |
Brain catecholamine alterations and pathological features with aging in Parkinson disease model rat induced by Japanese encephalitis virus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Brain Chemistry; Catecholamines; Dopamine; En | 2006 |
Tranylcypromine enhancement of nicotine self-administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Benzazepines; Chromatography, High Pressure Liquid; | 2007 |
Activated microglia affect the nigro-striatal dopamine neurons differently in neonatal and aged mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animal | 2007 |
Aging and sex differences in striatal dopaminergic function.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amphetamine; Animals; Dopamine; Dopamine Uptake Inhibitors; F | 2007 |
[Biochemical changes in 24-month-old Wistar rats].
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholinesterase; Aging; Animals; Choline; Choline O-Acetyltrans | 1984 |
Regional changes in monoamine metabolism in the aging constant estrous rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Corpus Striatum; Dopamine; Estrus; Female; Ho | 1984 |
Influence of chronic inorganic lead exposure on regional dopamine and 5-hydroxytryptamine turnover in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Dopamine; Erythrocytes; Female; Homovanillic | 1984 |
Changes in monoamines and their metabolite levels in some brain regions of aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Dopamine; Homovanillic Acid; Hydroxyindoleace | 1982 |
[Concentrations of monoamines and monoamine metabolites in cerebrospinal fluid determined by high-performance liquid chromatography with electrochemical detection].
Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Aged; Aging; Biogenic Amines; Chromatography, Hig | 1982 |
Rat dopaminergic function in the retina during aging.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Binding Sites; Corpus Striatum; Enkephalins; Male; P | 1981 |
Effect of suloctidil on dopaminergic transmission in various rat brain areas: possible uses as drug for the elderly.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Male; Propanolamines; Rats; Rats, Inbred Stra | 1983 |
Catecholamine levels and turnover during aging in brain regions of male C57BL/6J mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Catecholamines; Dopamine; Epinephrine; Mice; | 1981 |
Aging and haloperidol-induced dopamine turnover in the nigro-striatal pathway of C57BL/6J mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; Haloperidol; Male; Methyl | 1981 |
The effects of morphine on catecholamine metabolism during postnatal development.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Medulla; Aging; Animals; Catecholamines; Corpus Striatum; Do | 1980 |
Aging process affects a single class of dopamine receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Aging; Animals; Corpus Striatum; Haloperidol; Hum | 1980 |
Age-related changes on monoamine turnover in hippocampus of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Hippocampus; Hydroxyindoleacetic Acid; Imm | 1993 |
Changes in dopamine, serotonin and their metabolites in discrete brain areas of rat offspring after in utero exposure to cocaine or related drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amitriptyline; Amygdala; Analysis of Variance; Animals; Brain | 1993 |
Dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Caudate Nucleus; Disease Models, Animal; Dopa | 1994 |
Effect of ageing on monoamine turnover in the prefrontal cortex of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hy | 1993 |
Systemic or local administration of azide produces striatal lesions by an energy impairment-induced excitotoxic mechanism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine Triphosphate; Aging; Animals; Azides; Biogenic Amines; Cor | 1994 |
Aging and the nigrostriatal dopamine system: a non-human primate study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analys | 1994 |
Effects of deprenyl on monoamine oxidase and neurotransmitters in the brains of MPTP-treated aging mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; | 1995 |
Neurochemical changes related to ageing in the senescence-accelerated mouse brain and the effect of chronic administration of nimodipine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Administration, Oral; Aging; Animals; Brain; Calcium | 1995 |
A decreased tubular uptake of dopa results in defective renal dopamine production in aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Biological Tra | 1995 |
Postnatal exposure to the beta-adrenoceptor agonist clenbuterol has regionally selective direct and long-term effects on rat brain beta-adrenoceptors and monoamine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Brain; Cerebellum; Clenbuterol; Do | 1993 |
Development of dopamine and N-methyl-D-aspartate systems in rat brain: the effect of prenatal phencyclidine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Female; | 1993 |
Effects of genotype on age-related alterations in the concentrations of stress hormones in plasma and hypothalamic monoamines in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenocorticotropic Hormone; Aging; Animals; Biogenic Monoamines; Co | 1993 |
Effects of age and dopamine agonists and antagonists on striatal dopamine release in the rat: an in vivo microdialysis study.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dialys | 1993 |
Effects of EEDQ on the synthesis and metabolism of dopamine in preweanling and adult rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Suckling; Dihydroxyphenylalanine; Dopamine; | 1994 |
MPTP-induced oxidative stress and neurotoxicity are age-dependent: evidence from measures of reactive oxygen species and striatal dopamine levels.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Homovanillic Acid; Male; Mice; Mice, Inbre | 1994 |
Motor behavior and nigrostriatal dopaminergic activity in adult rats perinatally exposed to cannabinoids.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Cannabinoids; Cannabis; Corpus Str | 1994 |
Comparison of brain dopamine depletion induced by low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in young and aged rats.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; | 1994 |
[Age-related changes in the dopaminergic system in rat striatum].
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Basal Metabolism; Corpus Striatum; Dopamine; Homovan | 1993 |
Estradiol derived from testosterone in prenatal life affects the development of catecholamine systems in the frontal cortex in the male rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Aromatase Inhibitors; Catecholamin | 1994 |
Effects of a cold environment or age on methamphetamine-induced dopamine release in the caudate putamen of female rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Caudate Nucleus; Chromatography | 1993 |
Ontogeny of enhanced striatal dopamine release in rats with methamphetamine-induced behavioral sensitization.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Behavior, Animal; Brain Chemistry; Chromatography, H | 1994 |
Monoamine concentrations in cerebrospinal fluid of fetal and newborn sheep.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Biogenic Monoamines; Dinoprostone; | 1994 |
Calcium dependency and tetrodotoxin sensitivity of neostriatal dopamine release in 5-day-old and adult rats as measured by in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Calcium; Dopamine; Kinetics; Micro | 1994 |
Developmental differences in acute nigrostriatal and mesocorticolimbic system response to haloperidol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; Dose-Response Relationshi | 1993 |
The ontogeny of apomorphine-induced alterations of neostriatal dopamine release: effects on spontaneous release.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Apomorphine; Corpus Striatum; Dopamine; Dose-Respons | 1993 |
Effects of ageing on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxic effects on striatum and brainstem in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Antioxidants; Ascorbic Acid; Brain Stem; Corpus Stri | 1993 |
Neonatal lateralization of behavior and brain dopaminergic asymmetry.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Dopamine; Female; Functional Later | 1993 |
Ischemia-induced changes in brain monoamine metabolism in aged spontaneously hypertensive rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Brain; Corpus Striatum; Dopamin | 1993 |
Age-related effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment of common marmosets.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Brain Chemistry; Callithrix; Chromatography, | 1993 |
Venous plasma noradrenaline increases with age: correlation to total blood volume and long-term smoking habits.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Aged, 80 and over; Aging; Benserazide; Blood Volume; Bo | 1993 |
Effects of postnatal stress on dopamine mesolimbic system responses to aversive experiences in adult life.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Animals; Apomorphine; Dopamine; Female; | 1993 |
Effects of estrogen upon dopamine release from the corpus striatum of young and aged female rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amphetamine; Animals; Corpus Striatum; Dopamine; Estrogens; F | 1993 |
Altered in vivo catecholamine release in the hypothalamic paraventricular nucleus of the aged rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Catecholamines; Homovanillic Acid; Male; Norepinephr | 1996 |
Effects of chronic ethanol consumption and aging on dopamine, serotonin, and metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Alcohol Drinking; Animals; Brain; Dopamine; Hydroxyindoleacet | 1996 |
Age-related changes in the metabolism of neurotransmitters in rat striatum: a microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; Male; Microdialysis; Mono | 1996 |
Effect of buthionine sulfoximine, a synthesis inhibitor of the antioxidant glutathione, on the murine nigrostriatal neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Antioxidants; Buthionine Sulfoximine; Corpus Striatu | 1996 |
Free radical scavenging activity of the Japanese herbal medicine toki-shakuyaku-san (TJ-23) and its effect on superoxide dismutase activity, lipid peroxides, glutamate, and monoamine metabolites in aged rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amino Acids; Animals; Bepridil; Biogenic Monoamines; Biphenyl | 1996 |
Age-related changes in monoamines within the olfactory bulbs of the Fischer 344 male rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Dopamine; Male; Olfactory Bulb; | 1996 |
Aging effects on monoamines in rat medial vestibular and cochlear nuclei.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Anterior Hypothalamic Nucleus; Auditory Threshold; C | 1996 |
Effects of perinatal exposure to delta 9-tetrahydrocannabinol on the fetal and early postnatal development of tyrosine hydroxylase-containing neurons in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Brain; Dronabinol; Female; Gene Ex | 1996 |
Morphological and biochemical adaptations to unilateral dopamine denervation of the neostriatum in newborn rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Basal Ganglia; Denervation; Dopami | 1997 |
Neuropeptide Y and [Leu31,Pro34]neuropeptide Y potentiate potassium-induced noradrenaline release in the paraventricular nucleus of the aged rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Cerebral Ventricles; Drug Synergism; Homovanillic Ac | 1997 |
Preservation of autoreceptor-mediated increases in dopamine synthesis in aged mice with experimentally-induced parkinsonism.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Aromat | 1997 |
Chronic inhibition of the high-affinity dopamine uptake system increases oxidative damage to proteins in the aged rat substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Blotting, Western; Dopamine; Dopamine Uptake Inhibit | 1997 |
Pre/postnatal dopamine D1 receptor stimulation induces a differential reduction of serotonin levels in hippocampus and superior colliculus of puber rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Aging; A | 1997 |
Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Cortex; Aging; Analysis of Variance; Animals; Biogenic Monoa | 1997 |
In vitro studies of endogenous noradrenaline and NPY overflow from the rat hypothalamus during maturation and ageing.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; Animals; Calcium; Chromatography, High Pressure | 1998 |
Normal and drug-induced locomotor behavior in aging: comparison to evoked DA release and tissue content in fischer 344 rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; Aging; Animals; Brain Chemistry; Chrom | 1998 |
The effects of repeated alcohol exposure on the neurochemistry of the periadolescent nucleus accumbens septi.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Alcoholism; Animals; Dopamine; Dose-Response Relationship, Dr | 1998 |
Prenatal stress alters brain biogenic amine levels in primates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Behavior, Animal; Biogenic Amines; Brain; Female; Ho | 1998 |
Changes with age in daytime and nighttime contents of melatonin, indoleamines, and catecholamines in the pineal gland: a comparative study in rat and Syrian hamster.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aging; Animals; Catecholamines; Circadian Rhyth | 1998 |
Combined effect of obesity and aging on feeding-induced monoamine release in the rostromedial hypothalamus of the Zucker rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Dopamine; Eating; Food; Hydroxy | 1998 |
Microdialysis studies of basal levels and stimulus-evoked overflow of dopamine and metabolites in the striatum of young and aged Fischer 344 rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Animals; Corpus Striatum; Dextroampheta | 1999 |
Repeated cocaine exposure: effects on catecholamines in the nucleus accumbens septi of periadolescent animals.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Catecholamines; Cocaine; Dopamine; Dopamine Uptake I | 1999 |
An age-related decline in striatal taurine is correlated with a loss of dopaminergic markers.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biomarkers; Brain-Derived Neurotrophic Factor; Corpu | 1999 |
[Effect of acidic fibroblast growth factor on experimental parkinsonism and levels of dopamine and its metabolites in the striatum of mice of various ages].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Administration, Intran | 1999 |
GM1 ganglioside restores dopaminergic neurochemical and morphological markers in aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; G(M1) Ganglioside; Male; | 1999 |
Aging, high salt intake, and renal dopaminergic activity in Fischer 344 rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Animals; Aromatic-L-Amino-Acid Decarbox | 1999 |
Age-related dopamine deficiency in the mesostriatal dopamine system of zitter mutant rats: regional fiber vulnerability in the striatum and the olfactory tubercle.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Antibodies; Disease Models, Animal; Dopamine; Free R | 2000 |
Evaluation of L-DOPA biotransformation during repeated L-DOPA infusion into the striatum in freely-moving young and old rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Antiparkinson Agents; Chromatography, High Pressure | 2000 |
Age as a susceptibility factor in the striatal dopaminergic neurotoxicity observed in the mouse following substituted amphetamine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Area Under Curve; Body Temperature; Central Nervous | 2000 |
DNA damage in brain mitochondria caused by aging and MPTP treatment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; Animals; Brain Chemistry; DNA Damage; DNA, Mitoc | 2000 |
Effects of chronic bromocriptine treatment on tyrosine hydroxylase (TH) mRNA expression, TH activity and median eminence dopamine concentrations in ageing rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Arcuate Nucleus of Hypothalamus; Bromocriptine; Dopa | 2001 |
Changes in endogenous monoamines in aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Catechol O-Methyltransferase; C | 2001 |
Striatal dopamine sensitization to D-amphetamine in periadolescent but not in adult rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Caud | 2001 |
Neuroprotective effects of GDNF against 6-OHDA in young and aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Cell Survival; Dopamine; Glial Cell Line-Derived Neu | 2001 |
Carbachol effect on carotid body dopamine in vitro release in response to hypoxia in adult and pup rabbit.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Carbachol; Carotid Body; Cholinergic Agonists; Dopam | 2001 |
Neonatal dopamine depletion reveals a synergistic mechanism of mRNA regulation that is mediated by dopamine(D1) and serotonin(2) receptors and is targeted to tachykinin neurons of the dorsomedial striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Dopamine; Dopamine Agonists; Dopam | 2001 |
Heart failure, aging, and renal synthesis of dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Age Factors; Aged; Aging; Aldosterone; Cardiac Output, Low; C | 2001 |
Aging increases the susceptiblity to methamphetamine-induced dopaminergic neurotoxicity in rats: correlation with peroxynitrite production and hyperthermia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain Chemistry; Central Nervous System Stimulants; | 2001 |
Prenatal cocaine exposure increases mesoprefrontal dopamine neuron responsivity to mild stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Electr | 2001 |
Changes in the cochlear dopaminergic system of the aged rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Chromatography, High Pressure Liquid; Cochlea; Dopam | 2001 |
Effects of aging on cochlear monoamine turnover.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Chromatography, High Pressure L | 2002 |
Alterations of amino acids and monoamine metabolism in male Fmr1 knockout mice: a putative animal model of the human fragile X mental retardation syndrome.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain St | 2001 |
Serotonergic neurotoxicity of MDMA (ecstasy) in the developing rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Apoptosis; Brain; Dopamine; Female; Homovanillic Aci | 2002 |
Neonatal exposure to cocaine: altered dopamine levels in the amygdala and behavioral outcomes in the developing rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amygdala; Animals; Animals, Newborn; Cocaine; Dopamine; Femal | 2002 |
Determination of some L-3,4-dihydroxyphenylalanine and dopamine metabolites in urine by means of mass fragmentography.
Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Adult; Aging; Child; Child, Presch | 1978 |
Age-related changes in catecholamine metabolites of human urine from birth to adulthood.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adolescent; Adult; Aging; Catecholamines; Child; Child, Preschool; D | 1979 |
Postnatal development of dopamine deamination in the striatum of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Deamination; Dopamine; Female; Homo | 1975 |
Effect of alpha-human atrial natriuretic peptide on the synthesis of dopamine in the rat kidney.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3',5'-Cyclic-GMP Phosphodiesterases; Aging; Animals; Atrial Natriure | 1992 |
Comparisons between brain dopaminergic neurons of juvenile and aged rats: sex-related differences.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Dopamine; Female; Male; Neurons; Rats; Rats, | 1992 |
Slow changes of tyrosine hydroxylase gene expression in dopaminergic brain neurons after neurotoxin lesioning: a model for neuron aging.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amino Acid Sequence; Animals; Biogenic Monoamines; Corpus Str | 1992 |
Dopaminergic neuron development in rats: biochemical study from prenatal life to adulthood.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Female; Hydroxyindoleacetic Acid; Mesencep | 1992 |
Effects of age on GM1 ganglioside-induced recovery of concentrations of dopamine in the striatum in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus | 1992 |
Neuroendocrine responses to social regulation of puberty in the female house mouse.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Estradiol; Female; Hypothalamus; Hypothala | 1992 |
[Development in the metabolism of dopamine and its derivatives. Application to gross development disorders].
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Autistic Disorder; Child; Child, Presch | 1992 |
Regional brain monoamine levels and utilization in middle-aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Brain; Dopamine; Hydroxyindolea | 1990 |
Dopamine depletion in neonatal rats: effects on behavior and striatal dopamine release assessed by intracerebral microdialysis during adulthood.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Behavior, Animal; Corpus Striatum; | 1990 |
Turnover of dopamine and serotonin and their metabolites in the striatum of aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydraz | 1991 |
Neuropeptide levels in the basal ganglia of aged common marmosets following prolonged treatment with MPTP.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Basal | 1991 |
Transmitter synthesis increases in substantia nigra neurons of the aged mouse.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Axonal Transport; Corpus Striatum; Dihydroxyphenylal | 1991 |
Age effects on monoamine turnover of the rat substantia nigra.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aging; Animals; Aromatic Amino Acid Decarboxyla | 1991 |
Striatal dopamine release in vitro from immature male rats shows enhanced responsiveness to pulsatile, but not continuous, infusions of L-dopa.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; Levodopa; Male; Pulsatile | 1991 |
A study on the renal synthesis of dopamine in aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Chromatography, High Pressure Liquid; Dopamine; Kidn | 1991 |
Sucrose feeding at weaning alters the preference for sucrose in adolescence.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Chromatography, High Pressure Liquid; Dopamine; Drin | 1991 |
Effect of aging and diet restriction on monoamines and amino acids in cerebral cortex of Fischer-344 rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amino Acids; Animals; Biogenic Monoamines; Cerebral Cortex; C | 1991 |
The relationship between age and venous plasma concentrations of noradrenaline, catecholamine metabolites, DOPA and neuropeptide Y-like immunoreactivity in normal human subjects.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Catecholamine | 1991 |
The effect of long-term treatment with deprenyl on basal and L-dopa evoked dopamine release in vitro from the corpus striatum of aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amphetamine; Animals; Corpus Striatum; Dopamine; In Vitro Tec | 1991 |
Long-term effect of MPTP in the mouse brain in relation to aging: neurochemical and immunocytochemical analysis.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; | 1990 |
Differential effect of aging on 3H-SCH 23390 binding sites in the retina and in distinct areas of the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Benzazepines; Brain Chemistry; Cerebral Cortex; Corp | 1990 |
Development of haloperidol-induced dopamine release in the rat striatum using intracerebral dialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dialysis; Dopamine; Female; Haloper | 1990 |
Vesicular and ganglionic norepinephrine in the rat: progressive increase with age.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Catecholamines; Chromatography, High Pressure | 1990 |
In vivo autoxidation of dopamine in guinea pig striatum increases with age.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Cerebral Cortex; Corpus Striatum; Cysteinyldo | 1990 |
Effect of aging on monoamines and their metabolites in the rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Brain Chemistry; Dopamine; Homovanillic Acid; | 1987 |
Effect of dopamine-depleting brain lesions in rat pups: role of striatal serotonergic neurons in behavior.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Behavior, Animal; Brain; Corpus St | 1987 |
Changes in biogenic amines in rat hippocampus during development and aging.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aging; Animals; Dopamine; Hippocampus; Homovani | 1988 |
Brain monoamines and metabolites in hypertensive and hyperactive rat strains.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Brain Chemistry; Dopamine; Fema | 1988 |
Analysis of equine cisterna magna cerebrospinal fluid for the presence of some monoamine neurotransmitters and transmitter metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Monoamines; Cisterna Magna; Female; Homovan | 1989 |
A longitudinal study of the effect of different social rearing conditions on cerebrospinal fluid norepinephrine and biogenic amine metabolites in rhesus monkeys.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biogenic Amines; Female; Homovanillic Acid; Hydroxyi | 1989 |
Dopamine synthesis and metabolism in rhesus monkey retina: development, aging, and the effects of monocular visual deprivation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Dopamine; Macaca mulatta; Osmolar | 1989 |
Age-related changes of catecholamines and their metabolites content in the visual system of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Catecholamines; Dopamine; Geniculate Bodies; Homovan | 1989 |
Effect of mild postnatal hypoxia and L-dopa administration on dopamine concentration in striata of the newborn rat and long term sequelae on dopamine turnover.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Hypoxia | 1989 |
Developmental and age-related changes in D1-dopamine receptors and dopamine content in the rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Aging; Animals; Benzazepines; Binding Sites; Corp | 1987 |
Endurance training effects on striatal D2 dopamine receptor binding and striatal dopamine metabolites in presenescent older rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Kineti | 1987 |
Mechanism of age-related and nitrous oxide-associated anesthetic sensitivity: the role of brain catecholamines.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain Chemistry; Dopamine; Drug Resistance; Male; Mi | 1988 |
Long-term effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal dopamine content in young and mature mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus | 1987 |
The change with age in biogenic amines and their metabolites in the striatum of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; Animals; Biogenic Amines; Corpus Striatum; Dopam | 1986 |
Effect of nialamide on the metabolism of dopamine injected into the nucleus accumbens of old rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Homovanillic Acid; Limbic System; Male; Mo | 1986 |
Brain catecholamine content and turnover in aging rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; alpha-Methyltyrosine; Animals; Brain; Catecholamines; Corpus | 1985 |