3,4-dihydroxybenzohydroxamic acid and Neoplasms studies

3,4-dihydroxybenzohydroxamic acid and Neoplasms

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

Excerpt	Relevance	Reference
" Results of treatment of B16 melanoma and Lewis lung carcinoma with 3,4-dihydroxybenzohydroxamic acid are used to demonstrate this definition."	3.66	Drug activity and therapeutic synergism in cancer treatment. ( Campbell, ED; Carter, WH; Stablein, DM; Wampler, GL, 1982)
" Pharmacokinetic studies showed that a peak level of didox was achieved within 5 minutes of injection."	1.27	A phase 1 and pharmacokinetic study of didox: a ribonucleotide reductase inhibitor. ( Blackie, R; Cantwell, BM; Carmichael, J; Elford, HL; Harris, AL; Kaye, SB; Kerr, DJ; Veale, D, 1988)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (66.67)	18.7374
1990's	1 (33.33)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

2 (66.67)

18.7374

1990's

1 (33.33)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Carter, WH	1
Wampler, GL	1
Stablein, DM	1
Campbell, ED	1
Carmichael, J	2
Cantwell, BM	2
Mannix, KA	1
Veale, D	2
Elford, HL	2
Blackie, R	2
Kerr, DJ	2
Kaye, SB	2
Harris, AL	2

Studies

Carter, WH

Wampler, GL

Stablein, DM

Campbell, ED

Carmichael, J

Cantwell, BM

Mannix, KA

Veale, D

Elford, HL

Blackie, R

Kerr, DJ

Kaye, SB

Harris, AL

Trials

1 trial available for 3,4-dihydroxybenzohydroxamic acid and Neoplasms

Article	Year
A phase I and pharmacokinetic study of didox administered by 36 hour infusion. The Cancer Research Campaign Phase I/II Clinical Trials Committee. British journal of cancer, 1990, Volume: 61, Issue:3 Topics: Adult; Aged; Drug Administration Schedule; Drug Evaluation; Female; Humans; Hydroxamic Acids; Infusi	1990

Article

Year

A phase I and pharmacokinetic study of didox administered by 36 hour infusion. The Cancer Research Campaign Phase I/II Clinical Trials Committee.

British journal of cancer, 1990, Volume: 61, Issue:3

Topics: Adult; Aged; Drug Administration Schedule; Drug Evaluation; Female; Humans; Hydroxamic Acids; Infusi

1990

Other Studies

2 other studies available for 3,4-dihydroxybenzohydroxamic acid and Neoplasms

Article	Year
Drug activity and therapeutic synergism in cancer treatment. Cancer research, 1982, Volume: 42, Issue:8 Topics: Animals; Antineoplastic Agents; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration S	1982
A phase 1 and pharmacokinetic study of didox: a ribonucleotide reductase inhibitor. British journal of cancer, 1988, Volume: 58, Issue:1 Topics: Adult; Aged; Drug Evaluation; Female; Humans; Hydroxamic Acids; Liver Function Tests; Male; Middle A	1988

Article

Year

Drug activity and therapeutic synergism in cancer treatment.

Cancer research, 1982, Volume: 42, Issue:8

Topics: Animals; Antineoplastic Agents; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration S

1982

A phase 1 and pharmacokinetic study of didox: a ribonucleotide reductase inhibitor.

British journal of cancer, 1988, Volume: 58, Issue:1

Topics: Adult; Aged; Drug Evaluation; Female; Humans; Hydroxamic Acids; Liver Function Tests; Male; Middle A

1988