3,4-dihydroxybenzohydroxamic acid has been researched along with AIDS, Murine in 5 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, the novel RR inhibitors didox (DX; 3,4-dihydroxybenzohydroxamic acid), and trimidox (TX; 3,4,5-trihydroxybenzamidoxime) were evaluated along with HU for anti-retroviral efficacy in LPBM5-induced retro-viral disease (MAIDS) both as monotherapeutic regimens and in combination with the guanine containing NRTI abacavir (ABC)." | 1.32 | In vivo examination of hydroxyurea and the novel ribonucleotide reductase inhibitors trimidox and didox in combination with the reverse transcriptase inhibitor abacavir: suppression of retrovirus-induced immunodeficiency disease. ( Duvall, W; Elford, HL; Gallicchio, VS; Hagan, E; Inayat, MS; Mayhew, CN; Sumpter, LR; Yost, EE, 2004) |
| " However, appeal for the long-term use of HU in HIV-1 infection may be limited by its propensity to induce hematopoietic toxicity." | 1.31 | Suppression of retrovirus-induced immunodeficiency disease (murine AIDS) by trimidox and didox: novel ribonucleotide reductase inhibitors with less bone marrow toxicity than hydroxyurea. ( Ahmed, MM; Chendil, D; Elford, HL; Gallicchio, VS; Greenberg, RN; Mampuru, LJ; Mayhew, CN; Phillips, JD, 2002) |
| " We examined a new series of RRIs, 3,4-dihydroxybenzohydroxamic acid (Didox) and 3,4,5-trihydroxybenzohydroxamidoxime (Trimidox) for their ability to alter disease progression in murine acquired immunodeficiency syndrome (MAIDS), both alone and in combination with 2',3'-dideoxyinosine (ddI)." | 1.30 | Effective use of ribonucleotide reductase inhibitors (Didox and Trimidox) alone or in combination with didanosine (ddI) to suppress disease progression and increase survival in murine acquired immunodeficiency syndrome (MAIDS). ( Birch, NJ; Elford, HL; Gallicchio, VS; Hughes, NK; Mayhew, C; Oakley, O; Phillips, J; Piper, J, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mayhew, CN | 3 |
| Mampuru, LJ | 1 |
| Chendil, D | 1 |
| Ahmed, MM | 1 |
| Phillips, JD | 2 |
| Greenberg, RN | 1 |
| Elford, HL | 4 |
| Gallicchio, VS | 4 |
| Sumpter, LR | 1 |
| Inayat, MS | 1 |
| Yost, EE | 1 |
| Duvall, W | 1 |
| Hagan, E | 1 |
| Sumpter, R | 1 |
| Inayat, M | 1 |
| Cibull, M | 1 |
| Mayhew, C | 1 |
| Oakley, O | 1 |
| Piper, J | 1 |
| Hughes, NK | 1 |
| Phillips, J | 1 |
| Birch, NJ | 1 |
| Smart, T | 1 |
5 other studies available for 3,4-dihydroxybenzohydroxamic acid and AIDS, Murine
| Article | Year |
|---|---|
Suppression of retrovirus-induced immunodeficiency disease (murine AIDS) by trimidox and didox: novel ribonucleotide reductase inhibitors with less bone marrow toxicity than hydroxyurea.
Topics: Animals; Benzamidines; Bone Marrow Cells; DNA, Viral; Female; Femur; Free Radical Scavengers; Hemato | 2002 |
In vivo examination of hydroxyurea and the novel ribonucleotide reductase inhibitors trimidox and didox in combination with the reverse transcriptase inhibitor abacavir: suppression of retrovirus-induced immunodeficiency disease.
Topics: Animals; Antiviral Agents; Benzamidines; Bone Marrow Cells; Dideoxynucleosides; Disease Models, Anim | 2004 |
Combination of inhibitors of lymphocyte activation (hydroxyurea, trimidox, and didox) and reverse transcriptase (didanosine) suppresses development of murine retrovirus-induced lymphoproliferative disease.
Topics: Animals; Antiviral Agents; B-Lymphocytes; Benzamidines; Didanosine; Drug Therapy, Combination; Enzym | 2005 |
Effective use of ribonucleotide reductase inhibitors (Didox and Trimidox) alone or in combination with didanosine (ddI) to suppress disease progression and increase survival in murine acquired immunodeficiency syndrome (MAIDS).
Topics: Animals; Antiviral Agents; Benzamidines; Biomarkers; Didanosine; Disease Progression; Drug Therapy, | 1997 |
Beyond hydroxyurea.
Topics: Animals; Antiviral Agents; Benzamidines; Dipyridamole; Disease Models, Animal; Floxuridine; Fluorour | 1995 |