3,3'-diindolylmethane has been researched along with Thyroid Neoplasms in 4 studies
3,3'-diindolylmethane: anti-inflammatory from edible cruciferous vegetables; a cytochrome P-450 antagonist
Thyroid Neoplasms: Tumors or cancer of the THYROID GLAND.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The incidence of thyroid cancer is four to five times higher in women than in men, suggesting a role for estrogen (E₂) in the pathogenesis of thyroid proliferative disease (TPD) that comprises cancer and goiter." | 2.76 | 3,3'-diindolylmethane modulates estrogen metabolism in patients with thyroid proliferative disease: a pilot study. ( Bradlow, HL; Geliebter, J; Megwalu, U; Moscatello, A; Parmar, PS; Rajoria, S; Schantz, SP; Sepkovic, DW; Suriano, R; Tiwari, RK; Wilson, YL, 2011) |
| "In this study, three human thyroid cancer cells (B-CPAP, CGTH-W-1, ML-1) were treated with estrogen alone or estrogen and anti-estrogens (fulvestrant and 3,3'-diindolylmethane, a natural dietary compound) for 24 hours." | 1.38 | Molecular target based combinational therapeutic approaches in thyroid cancer. ( Geliebter, J; George, AL; Kamat, A; Rajoria, S; Schantz, SP; Suriano, R; Tiwari, RK, 2012) |
| "Current treatments for thyroid cancer, such as surgery or radioactive iodine therapy, often require patients to be on lifelong thyroid hormone replacement therapy and given the significant recurrence rates of thyroid cancer, new preventive modalities are needed." | 1.37 | Estrogen induced metastatic modulators MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in thyroid cancer. ( Geliebter, J; George, A; Rajoria, S; Schantz, SP; Shanmugam, A; Suriano, R; Tiwari, RK, 2011) |
| "We have been studying the anti-thyroid cancer (TCa) activity of indole-3-carbinol (I3C) found in cruciferous vegetables and its acid catalyzed dimer, 3,3'-diindolylmethane (DIM)." | 1.33 | 3,3'-Diindolylmethane, a cruciferous vegetable derived synthetic anti-proliferative compound in thyroid disease. ( Ashok, BT; Chang, Y; Chen, Y; Geliebter, J; Moscatello, A; Policastro, AJ; Schaefer, SD; Schantz, SP; Tadi, K; Tiwari, RK, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rajoria, S | 3 |
| Suriano, R | 3 |
| Parmar, PS | 1 |
| Wilson, YL | 1 |
| Megwalu, U | 1 |
| Moscatello, A | 2 |
| Bradlow, HL | 1 |
| Sepkovic, DW | 1 |
| Geliebter, J | 4 |
| Schantz, SP | 4 |
| Tiwari, RK | 4 |
| George, A | 1 |
| Shanmugam, A | 1 |
| George, AL | 1 |
| Kamat, A | 1 |
| Tadi, K | 1 |
| Chang, Y | 1 |
| Ashok, BT | 1 |
| Chen, Y | 1 |
| Schaefer, SD | 1 |
| Policastro, AJ | 1 |
1 trial available for 3,3'-diindolylmethane and Thyroid Neoplasms
| Article | Year |
|---|---|
3,3'-diindolylmethane modulates estrogen metabolism in patients with thyroid proliferative disease: a pilot study.
Topics: Estrogens; Female; Humans; Indoles; Pilot Projects; Thyroid Gland; Thyroid Neoplasms; Thyroidectomy | 2011 |
3 other studies available for 3,3'-diindolylmethane and Thyroid Neoplasms
| Article | Year |
|---|---|
Estrogen induced metastatic modulators MMP-2 and MMP-9 are targets of 3,3'-diindolylmethane in thyroid cancer.
Topics: Anticarcinogenic Agents; Cell Adhesion; Cell Line, Tumor; Cell Movement; Estrogen Receptor alpha; Es | 2011 |
Molecular target based combinational therapeutic approaches in thyroid cancer.
Topics: Antibodies, Neutralizing; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Mov | 2012 |
3,3'-Diindolylmethane, a cruciferous vegetable derived synthetic anti-proliferative compound in thyroid disease.
Topics: Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Respon | 2005 |