Page last updated: 2024-10-26

3,3'-diindolylmethane and Precancerous Conditions

3,3'-diindolylmethane has been researched along with Precancerous Conditions in 1 studies

3,3'-diindolylmethane: anti-inflammatory from edible cruciferous vegetables; a cytochrome P-450 antagonist

Precancerous Conditions: Pathological conditions that tend eventually to become malignant.

Research Excerpts

ExcerptRelevanceReference
"In C33A cervical cancer cells, DIM was more potent than I3C [dose at which the number of viable cells was 50% of that in untreated cultures (LD(50)) = 50-60 micromol/L for DIM and 200 micromol/L for I3C in a mitochondrial function assay] and faster acting."1.31Indole-3-carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16-transgenic preneoplastic cervical epithelium. ( Auborn, KJ; Carter, TH; Chen, DZ; Qi, M, 2001)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, DZ1
Qi, M1
Auborn, KJ1
Carter, TH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Single-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of 3,3'-Diindolylmethane (BR-DIM) in Patients With Systemic Lupus Erythematosus (SLE)[NCT02483624]Phase 16 participants (Actual)Interventional2016-01-31Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for 3,3'-diindolylmethane and Precancerous Conditions

ArticleYear
Indole-3-carbinol and diindolylmethane induce apoptosis of human cervical cancer cells and in murine HPV16-transgenic preneoplastic cervical epithelium.
    The Journal of nutrition, 2001, Volume: 131, Issue:12

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspases; DNA Fragmentati

2001