3,3'-diindolylmethane has been researched along with Parkinsonian Disorders in 1 studies
3,3'-diindolylmethane: anti-inflammatory from edible cruciferous vegetables; a cytochrome P-450 antagonist
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We postulated that the pharmacokinetic behavior of C-DIM compounds after oral administration would correlate with neuroprotective efficacy in vivo in a mouse model of Parkinson's disease." | 1.39 | Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson's disease. ( Colagiovanni, D; De Miranda, BR; Gustafson, DL; Hansen, RJ; Lunghofer, PJ; Miller, JA; Safe, S; Tjalkens, RB, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Miranda, BR | 1 |
| Miller, JA | 1 |
| Hansen, RJ | 1 |
| Lunghofer, PJ | 1 |
| Safe, S | 1 |
| Gustafson, DL | 1 |
| Colagiovanni, D | 1 |
| Tjalkens, RB | 1 |
1 other study available for 3,3'-diindolylmethane and Parkinsonian Disorders
| Article | Year |
|---|---|
Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson's disease.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Chromatography, High Pressure Liquid; Corpu | 2013 |