3,3'-diindolylmethane has been researched along with Necrosis in 1 studies
3,3'-diindolylmethane: anti-inflammatory from edible cruciferous vegetables; a cytochrome P-450 antagonist
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In conclusion, ring-DIMs inhibited prostate cancer cell growth and induced cell death in LNCaP and PC-3 cells with greater potencies than DIM; they also structure-dependently activated different cell death pathways suggesting that these compounds have clinical potential as chemopreventive and chemotherapeutic agents in prostate cancer, regardless of hormone-dependency." | 5.40 | Ring-substituted analogs of 3,3'-diindolylmethane (DIM) induce apoptosis and necrosis in androgen-dependent and -independent prostate cancer cells. ( Abdelbaqi, K; Beach, A; Goldberg, AA; Safe, S; Sanderson, JT; Titorenko, VI, 2014) |
| "In conclusion, ring-DIMs inhibited prostate cancer cell growth and induced cell death in LNCaP and PC-3 cells with greater potencies than DIM; they also structure-dependently activated different cell death pathways suggesting that these compounds have clinical potential as chemopreventive and chemotherapeutic agents in prostate cancer, regardless of hormone-dependency." | 1.40 | Ring-substituted analogs of 3,3'-diindolylmethane (DIM) induce apoptosis and necrosis in androgen-dependent and -independent prostate cancer cells. ( Abdelbaqi, K; Beach, A; Goldberg, AA; Safe, S; Sanderson, JT; Titorenko, VI, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldberg, AA | 1 |
| Titorenko, VI | 1 |
| Beach, A | 1 |
| Abdelbaqi, K | 1 |
| Safe, S | 1 |
| Sanderson, JT | 1 |
1 other study available for 3,3'-diindolylmethane and Necrosis
| Article | Year |
|---|---|
Ring-substituted analogs of 3,3'-diindolylmethane (DIM) induce apoptosis and necrosis in androgen-dependent and -independent prostate cancer cells.
Topics: Androgens; Apoptosis; Caspase 3; Caspase 8; Cell Line, Tumor; Cell Proliferation; Dihydrotestosteron | 2014 |