3,3'-diindolylmethane has been researched along with Melanoma in 3 studies
3,3'-diindolylmethane: anti-inflammatory from edible cruciferous vegetables; a cytochrome P-450 antagonist
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, we investigated the anti-cancer effect of the phytochemicals kaempferol (Kaem), genistein (Gen), and 3'3-diindolylmethane (DIM) on melanoma cell viability." | 3.88 | Phytochemical-induced reactive oxygen species and endoplasmic reticulum stress-mediated apoptosis and differentiation in malignant melanoma cells. ( Choi, KC; Heo, JR; Hwang, KA; Kim, GS; Lee, GA, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Maciejewska, D | 1 |
| Rasztawicka, M | 1 |
| Wolska, I | 1 |
| Anuszewska, E | 1 |
| Gruber, B | 1 |
| Wang, X | 1 |
| Zhao, Y | 1 |
| Yu, M | 1 |
| Xu, Y | 1 |
| Heo, JR | 1 |
| Lee, GA | 1 |
| Kim, GS | 1 |
| Hwang, KA | 1 |
| Choi, KC | 1 |
3 other studies available for 3,3'-diindolylmethane and Melanoma
| Article | Year |
|---|---|
Novel 3,3'-diindolylmethane derivatives: synthesis and cytotoxicity, structural characterization in solid state.
Topics: Anticarcinogenic Agents; Cell Line; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumo | 2009 |
PTEN/Akt Signaling-Mediated Activation of the Mitochondrial Pathway Contributes to the 3,3'-Diindolylmethane-Mediated Antitumor Effect in Malignant Melanoma Cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Indoles; Melanoma; Proto-Oncogene Proteins | 2020 |
Phytochemical-induced reactive oxygen species and endoplasmic reticulum stress-mediated apoptosis and differentiation in malignant melanoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Differentiation; Cell Line, Tumor; Endoplasmic Re | 2018 |