3,3'-diindolylmethane has been researched along with Liver Neoplasms in 8 studies
3,3'-diindolylmethane: anti-inflammatory from edible cruciferous vegetables; a cytochrome P-450 antagonist
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Late stage hepatocellular carcinoma (HCC) usually has a low survival rate because it has high potential of metastases and there is no effective cure." | 5.42 | 3'3-Diindolylmethane inhibits migration, invasion and metastasis of hepatocellular carcinoma by suppressing FAK signaling. ( Chen, LP; Li, JT; Li, WX; Liu, HZ; Sun, MY; Zhu, W, 2015) |
| "Late stage hepatocellular carcinoma (HCC) usually has a low survival rate because it has high potential of metastases and there is no effective cure." | 1.42 | 3'3-Diindolylmethane inhibits migration, invasion and metastasis of hepatocellular carcinoma by suppressing FAK signaling. ( Chen, LP; Li, JT; Li, WX; Liu, HZ; Sun, MY; Zhu, W, 2015) |
| "In cultured human hepatoma HepG2 cells, DIM blocked DNA synthesis and mitosis in a concentration-dependent manner, which was consistent with the outcome of topoisomerase inhibition in these cell-cycle phases." | 1.33 | 3,3'-diindolylmethane is a novel topoisomerase IIalpha catalytic inhibitor that induces S-phase retardation and mitotic delay in human hepatoma HepG2 cells. ( Bjeldanes, LF; Firestone, GL; Gong, Y, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Munakarmi, S | 1 |
| Shrestha, J | 1 |
| Shin, HB | 1 |
| Lee, GH | 1 |
| Jeong, YJ | 1 |
| Hoffman, TE | 1 |
| Acerbo, ER | 1 |
| Carranza, KF | 1 |
| Gilberto, VS | 1 |
| Wallis, LE | 1 |
| Hanneman, WH | 1 |
| Zhu, W | 2 |
| Liu, Y | 1 |
| Hu, K | 1 |
| Li, W | 1 |
| Chen, J | 1 |
| Li, J | 1 |
| Yang, G | 1 |
| Wu, J | 1 |
| Liang, X | 1 |
| Fu, C | 1 |
| Hu, Q | 1 |
| Li, WX | 1 |
| Chen, LP | 1 |
| Sun, MY | 1 |
| Li, JT | 1 |
| Liu, HZ | 1 |
| Cheng, JS | 1 |
| Shu, SS | 1 |
| Kuo, CC | 1 |
| Chou, CT | 1 |
| Tsai, WL | 1 |
| Fang, YC | 1 |
| Kuo, LN | 1 |
| Yeh, JH | 1 |
| Chen, WC | 1 |
| Chien, JM | 1 |
| Lu, T | 1 |
| Pan, CC | 1 |
| Cheng, HH | 1 |
| Chai, KL | 1 |
| Jan, CR | 1 |
| Saw, CL | 1 |
| Cintrón, M | 1 |
| Wu, TY | 1 |
| Guo, Y | 1 |
| Huang, Y | 1 |
| Jeong, WS | 1 |
| Kong, AN | 1 |
| Gong, Y | 1 |
| Firestone, GL | 1 |
| Bjeldanes, LF | 1 |
| Tilton, SC | 1 |
| Hendricks, JD | 1 |
| Orner, GA | 1 |
| Pereira, CB | 1 |
| Bailey, GS | 1 |
| Williams, DE | 1 |
8 other studies available for 3,3'-diindolylmethane and Liver Neoplasms
| Article | Year |
|---|---|
3,3'-Diindolylmethane Suppresses the Growth of Hepatocellular Carcinoma by Regulating Its Invasion, Migration, and ER Stress-Mediated Mitochondrial Apoptosis.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Carcinoma, He | 2021 |
Ultrasensitivity dynamics of diverse aryl hydrocarbon receptor modulators in a hepatoma cell line.
Topics: Animals; Benzo(a)pyrene; Carcinoma, Hepatocellular; Cell Line, Tumor; Hazardous Substances; Indoles; | 2019 |
Vitronectin [correction of Vitronetcin] promotes cell growth and inhibits apoptotic stimuli in a human hepatoma cell line via the activation of caspases.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; Caspases | 2014 |
3'3-Diindolylmethane inhibits migration, invasion and metastasis of hepatocellular carcinoma by suppressing FAK signaling.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Cell Mov | 2015 |
Effect of diindolylmethane on Ca(2+) movement and viability in HA59T human hepatoma cells.
Topics: Apoptosis; Calcium; Calcium Channel Blockers; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Surv | 2011 |
Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates.
Topics: Anticarcinogenic Agents; Antioxidants; Carcinoma, Hepatocellular; Drug Synergism; Gene Expression Re | 2011 |
3,3'-diindolylmethane is a novel topoisomerase IIalpha catalytic inhibitor that induces S-phase retardation and mitotic delay in human hepatoma HepG2 cells.
Topics: Antigens, Neoplasm; Carcinoma, Hepatocellular; Cell Line, Tumor; Comet Assay; DNA Topoisomerases, Ty | 2006 |
Gene expression analysis during tumor enhancement by the dietary phytochemical, 3,3'-diindolylmethane, in rainbow trout.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cell Transformation, Neop | 2007 |