3,3'-diindolylmethane has been researched along with Cirrhosis in 4 studies
3,3'-diindolylmethane: anti-inflammatory from edible cruciferous vegetables; a cytochrome P-450 antagonist
| Excerpt | Relevance | Reference |
|---|---|---|
| "3,3'-Diindolylmethane (DIM), a natural acid condensation extracted from cruciferous plants, exhibits anti-fibrotic effects in hepatic and cardiac fibrosis models." | 7.88 | 3,3'-Diindolylmethane ameliorates renal fibrosis through the inhibition of renal fibroblast activation in vivo and in vitro. ( Shi, L; Xi, JL; Xia, ZE, 2018) |
| "In both experiments, DIM reduced to cardiac hypertrophy and fibrosis induced by aortic banding through the activation of 5'-adenosine monophosphate-activated protein kinase-α2 (AMPKα2) and inhibition of mammalian target of the rapamycin (mTOR) signaling pathway." | 5.39 | 3,3'-Diindolylmethane protects against cardiac hypertrophy via 5'-adenosine monophosphate-activated protein kinase-α2. ( Bian, ZY; Dai, J; Deng, W; Guo, HP; Li, HL; Tang, QZ; Wu, QQ; Yuan, Y; Zhang, JY; Zhang, R; Zhang, Y; Zhou, H; Zong, J, 2013) |
| "3,3'-Diindolylmethane (DIM), a natural acid condensation extracted from cruciferous plants, exhibits anti-fibrotic effects in hepatic and cardiac fibrosis models." | 3.88 | 3,3'-Diindolylmethane ameliorates renal fibrosis through the inhibition of renal fibroblast activation in vivo and in vitro. ( Shi, L; Xi, JL; Xia, ZE, 2018) |
| "In both experiments, DIM reduced to cardiac hypertrophy and fibrosis induced by aortic banding through the activation of 5'-adenosine monophosphate-activated protein kinase-α2 (AMPKα2) and inhibition of mammalian target of the rapamycin (mTOR) signaling pathway." | 1.39 | 3,3'-Diindolylmethane protects against cardiac hypertrophy via 5'-adenosine monophosphate-activated protein kinase-α2. ( Bian, ZY; Dai, J; Deng, W; Guo, HP; Li, HL; Tang, QZ; Wu, QQ; Yuan, Y; Zhang, JY; Zhang, R; Zhang, Y; Zhou, H; Zong, J, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xia, ZE | 1 |
| Xi, JL | 1 |
| Shi, L | 1 |
| Li, J | 1 |
| Zhang, W | 1 |
| Jiao, R | 1 |
| Yang, Z | 1 |
| Yuan, Y | 2 |
| Wu, Q | 1 |
| Hu, Z | 1 |
| Xiang, S | 1 |
| Tang, Q | 1 |
| Zong, J | 1 |
| Deng, W | 1 |
| Zhou, H | 1 |
| Bian, ZY | 1 |
| Dai, J | 1 |
| Zhang, JY | 1 |
| Zhang, R | 1 |
| Zhang, Y | 1 |
| Wu, QQ | 1 |
| Guo, HP | 1 |
| Li, HL | 1 |
| Tang, QZ | 1 |
| Yao, Z | 1 |
| Hu, W | 1 |
| Yin, S | 1 |
| Huang, Z | 1 |
| Zhu, Q | 1 |
| Chen, J | 1 |
| Zang, Y | 1 |
| Dong, L | 1 |
| Zhang, J | 1 |
4 other studies available for 3,3'-diindolylmethane and Cirrhosis
| Article | Year |
|---|---|
3,3'-Diindolylmethane ameliorates renal fibrosis through the inhibition of renal fibroblast activation in vivo and in vitro.
Topics: Animals; Cadherins; Cell Line; Cell Proliferation; Fibronectins; Fibrosis; Indoles; Kidney; Kidney D | 2018 |
DIM attenuates TGF-β1-induced myofibroblast differentiation in neonatal rat cardiac fibroblasts.
Topics: Actins; Animals; Animals, Newborn; Cell Differentiation; Cell Proliferation; Cells, Cultured; Collag | 2015 |
3,3'-Diindolylmethane protects against cardiac hypertrophy via 5'-adenosine monophosphate-activated protein kinase-α2.
Topics: AMP-Activated Protein Kinases; Animals; Cardiomegaly; Cardiotonic Agents; Fibrosis; Indoles; Male; M | 2013 |
3,3'-Diindolymethane ameliorates adriamycin-induced cardiac fibrosis via activation of a BRCA1-dependent anti-oxidant pathway.
Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Blotting, Western; BRCA1 Protein; Cells, Culture | 2013 |