Compounds > 3,3'-diindolylmethane
Page last updated: 2024-10-26

3,3'-diindolylmethane and Cervix Dysplasia

3,3'-diindolylmethane has been researched along with Cervix Dysplasia in 7 studies

3,3'-diindolylmethane: anti-inflammatory from edible cruciferous vegetables; a cytochrome P-450 antagonist

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sepkovic, DW3
Stein, J2
Carlisle, AD2
Ksieski, HB2
Auborn, K2
Bradlow, HL3
Del Priore, G1
Gudipudi, DK1
Montemarano, N1
Restivo, AM1
Malanowska-Stega, J1
Arslan, AA1
Raucci, L1
Nyirenda, T1
Castañon, A2
Tristram, A2
Mesher, D1
Powell, N2
Beer, H1
Ashman, S1
Rieck, G1
Fielder, H1
Fiander, A2
Sasieni, P2
Lorincz, AT1
Brentnall, AR1
Vasiljević, N1
Scibior-Bentkowska, D1
Cuzick, J1
Auborn, KJ1
Bell, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Diindolylmethane (DIM) Dietary Supplementation: A Nonsurgical Treatment for Cervical Intraepithelial Neoplasia (CIN)[NCT00212381]Phase 362 participants (Anticipated)Interventional2000-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for 3,3'-diindolylmethane and Cervix Dysplasia

ArticleYear
Oral diindolylmethane (DIM): pilot evaluation of a nonsurgical treatment for cervical dysplasia.
    Gynecologic oncology, 2010, Volume: 116, Issue:3

    Topics: Administration, Oral; Adult; Double-Blind Method; Female; Humans; Indoles; Pilot Projects; Placebos;

2010
Effect of diindolylmethane supplementation on low-grade cervical cytological abnormalities: double-blind, randomised, controlled trial.
    British journal of cancer, 2012, Jan-03, Volume: 106, Issue:1

    Topics: Adult; Alphapapillomavirus; Anticarcinogenic Agents; Apoptosis; Double-Blind Method; Female; Humans;

2012
HPV16 L1 and L2 DNA methylation predicts high-grade cervical intraepithelial neoplasia in women with mildly abnormal cervical cytology.
    International journal of cancer, 2013, Aug-01, Volume: 133, Issue:3

    Topics: Capsid Proteins; Cervix Uteri; Colposcopy; DNA Methylation; DNA, Viral; Female; Human papillomavirus

2013

Other Studies

4 other studies available for 3,3'-diindolylmethane and Cervix Dysplasia

ArticleYear
Diindolylmethane inhibits cervical dysplasia, alters estrogen metabolism, and enhances immune response in the K14-HPV16 transgenic mouse model.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:11

    Topics: Animals; Anticarcinogenic Agents; Enzyme-Linked Immunosorbent Assay; Estrogens; Female; Immunity; In

2009
Results from a dose-response study using 3,3'-diindolylmethane in the K14-HPV16 transgenic mouse model: cervical histology.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans;

2011
Can indole-3-carbinol-induced changes in cervical intraepithelial neoplasia be extrapolated to other food components?
    The Journal of nutrition, 2006, Volume: 136, Issue:10

    Topics: Animals; Brassica; Female; Humans; Indoles; Randomized Controlled Trials as Topic; Uterine Cervical

2006
Quantitative determination of 3,3'-diindolylmethane in urine of individuals receiving indole-3-carbinol.
    Nutrition and cancer, 2001, Volume: 41, Issue:1-2

    Topics: Anticarcinogenic Agents; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Humans; Indoles; P

2001