3,3'-diindolylmethane has been researched along with Cell Transformation, Neoplastic in 4 studies
3,3'-diindolylmethane: anti-inflammatory from edible cruciferous vegetables; a cytochrome P-450 antagonist
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "DIM induces apoptosis in prostate cancer cells via the mitochondria- and death receptor-mediated pathways." | 5.37 | 3,3'-Diindolylmethane inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate model. ( Cho, HJ; Kim, EJ; Kim, JK; Park, JH; Park, SY, 2011) |
| "To determine if DIM has an antiinflammatory effect in vivo, we examined the therapeutic effects of DIM in dextran sodium sulfate (DSS)-induced experimental colitis and colitis-associated colon carcinogenesis induced by azoxymethane (AOM)/DSS in BALB/c mice." | 3.75 | 3,3'-diindolylmethane attenuates colonic inflammation and tumorigenesis in mice. ( Kang, YH; Kim, DH; Kim, JK; Kim, YH; Kwon, HS; Park, JH; Shin, EK; Shin, HK, 2009) |
| "The main reasons for the failure of most chemopreventive agents during clinical trials are poor in vivo bioavailability and dose-limiting side effects." | 1.39 | Chemoprevention of lung tumorigenesis by intranasally administered diindolylmethane in A/J mice. ( Kassie, F; Melkamu, T; Qian, X; Song, JM; Upadhyaya, P, 2013) |
| "DIM induces apoptosis in prostate cancer cells via the mitochondria- and death receptor-mediated pathways." | 1.37 | 3,3'-Diindolylmethane inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate model. ( Cho, HJ; Kim, EJ; Kim, JK; Park, JH; Park, SY, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, YH | 1 |
| Kwon, HS | 1 |
| Kim, DH | 1 |
| Shin, EK | 1 |
| Kang, YH | 1 |
| Park, JH | 2 |
| Shin, HK | 1 |
| Kim, JK | 2 |
| Cho, HJ | 1 |
| Park, SY | 1 |
| Kim, EJ | 1 |
| Qian, X | 1 |
| Song, JM | 1 |
| Melkamu, T | 1 |
| Upadhyaya, P | 1 |
| Kassie, F | 1 |
| Tilton, SC | 1 |
| Hendricks, JD | 1 |
| Orner, GA | 1 |
| Pereira, CB | 1 |
| Bailey, GS | 1 |
| Williams, DE | 1 |
4 other studies available for 3,3'-diindolylmethane and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
3,3'-diindolylmethane attenuates colonic inflammation and tumorigenesis in mice.
Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Body Weight; Carcinogens; Cell Transformation, Neopl | 2009 |
3,3'-Diindolylmethane inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate model.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Antigens, Polyomavirus Transforming; Apoptosis; Ap | 2011 |
Chemoprevention of lung tumorigenesis by intranasally administered diindolylmethane in A/J mice.
Topics: Administration, Intranasal; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Transform | 2013 |
Gene expression analysis during tumor enhancement by the dietary phytochemical, 3,3'-diindolylmethane, in rainbow trout.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cell Transformation, Neop | 2007 |