3,3'-diindolylmethane has been researched along with Adenocarcinoma in 9 studies
3,3'-diindolylmethane: anti-inflammatory from edible cruciferous vegetables; a cytochrome P-450 antagonist
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "DIM induces apoptosis in prostate cancer cells via the mitochondria- and death receptor-mediated pathways." | 5.37 | 3,3'-Diindolylmethane inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate model. ( Cho, HJ; Kim, EJ; Kim, JK; Park, JH; Park, SY, 2011) |
| "The administration of BR-DIM to prostate cancer patients before prostatectomy yields detectable plasma levels but without consistent or significant tissue accumulation or biomarker modulation." | 2.82 | Phase Ib placebo-controlled, tissue biomarker trial of diindolylmethane (BR-DIMNG) in patients with prostate cancer who are undergoing prostatectomy. ( Bailey, HH; Gee, JR; Harris, L; Havighurst, TC; House, M; Huang, W; Jarrard, D; Kim, K; Kolesar, J; Messing, E; Parnes, H; Saltzstein, DR; Wollmer, BW, 2016) |
| "DIM induces apoptosis in prostate cancer cells via the mitochondria- and death receptor-mediated pathways." | 1.37 | 3,3'-Diindolylmethane inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate model. ( Cho, HJ; Kim, EJ; Kim, JK; Park, JH; Park, SY, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gee, JR | 1 |
| Saltzstein, DR | 1 |
| Messing, E | 1 |
| Kim, K | 1 |
| Kolesar, J | 1 |
| Huang, W | 1 |
| Havighurst, TC | 1 |
| Harris, L | 1 |
| Wollmer, BW | 1 |
| Jarrard, D | 1 |
| House, M | 1 |
| Parnes, H | 1 |
| Bailey, HH | 1 |
| Khwaja, FS | 1 |
| Wynne, S | 1 |
| Posey, I | 1 |
| Djakiew, D | 1 |
| Bhatnagar, N | 1 |
| Li, X | 1 |
| Chen, Y | 1 |
| Zhou, X | 1 |
| Garrett, SH | 1 |
| Guo, B | 1 |
| Choi, HJ | 1 |
| Lim, DY | 1 |
| Park, JH | 2 |
| Cho, HJ | 1 |
| Park, SY | 1 |
| Kim, EJ | 1 |
| Kim, JK | 1 |
| Zhu, J | 1 |
| Li, Y | 1 |
| Guan, C | 1 |
| Chen, Z | 1 |
| Le, HT | 1 |
| Schaldach, CM | 1 |
| Firestone, GL | 3 |
| Bjeldanes, LF | 3 |
| Leong, H | 2 |
| Riby, JE | 1 |
1 trial available for 3,3'-diindolylmethane and Adenocarcinoma
| Article | Year |
|---|---|
Phase Ib placebo-controlled, tissue biomarker trial of diindolylmethane (BR-DIMNG) in patients with prostate cancer who are undergoing prostatectomy.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Biomarkers, Tumor; Double-Blind Method; Follow-Up Studies; | 2016 |
8 other studies available for 3,3'-diindolylmethane and Adenocarcinoma
| Article | Year |
|---|---|
3,3'-diindolylmethane induction of p75NTR-dependent cell death via the p38 mitogen-activated protein kinase pathway in prostate cancer cells.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents | 2009 |
3,3'-diindolylmethane enhances the efficacy of butyrate in colon cancer prevention through down-regulation of survivin.
Topics: Adenocarcinoma; Adenomatous Polyposis Coli; Animals; Anticarcinogenic Agents; Apoptosis; Butyrates; | 2009 |
Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3'-diindolylmethane in HT-29 human colon cancer cells.
Topics: Adenocarcinoma; Anticarcinogenic Agents; CDC2 Protein Kinase; Cell Cycle; Cell Division; Cell Line, | 2009 |
3,3'-Diindolylmethane inhibits prostate cancer development in the transgenic adenocarcinoma mouse prostate model.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Antigens, Polyomavirus Transforming; Apoptosis; Ap | 2011 |
Anti-proliferative and pro-apoptotic effects of 3,3'-diindolylmethane in human cervical cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell P | 2012 |
Plant-derived 3,3'-Diindolylmethane is a strong androgen antagonist in human prostate cancer cells.
Topics: Adenocarcinoma; Androgen Antagonists; Anilides; Animals; Anticarcinogenic Agents; Binding, Competiti | 2003 |
Potent ligand-independent estrogen receptor activation by 3,3'-diindolylmethane is mediated by cross talk between the protein kinase A and mitogen-activated protein kinase signaling pathways.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dep | 2004 |
Cytostatic effects of 3,3'-diindolylmethane in human endometrial cancer cells result from an estrogen receptor-mediated increase in transforming growth factor-alpha expression.
Topics: Adenocarcinoma; Alkaline Phosphatase; Anticarcinogenic Agents; Blotting, Northern; Blotting, Western | 2001 |