3,3',5-triiodothyroacetic acid has been researched along with Generalized Resistance to Thyroid Hormone in 14 studies
tiratricol : A monocarboxylic acid that is (4-hydroxy-3,5-diiodophenyl)acetic acid in which the phenolic hydroxy group has been replaced by a 4-hydroxy-3-iodophenoxy group. It is a thyroid hormone analogue that has been used in the treatment of thyroid hormone resistance syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the response of TSH secretion to 3,5,3'-triiodothyronine (T3) and 3,5,3'-triiodothyroacetic acid (Triac) in patients with resistance to thyroid hormone, and compared the responses with those in patients with TSH-secreting pituitary adenoma and normal subjects." | 3.69 | Differences in response of thyrotropin to 3,5,3'-triiodothyronine and 3,5,3'-triiodothyroacetic acid in patients with resistance to thyroid hormone. ( Fukata, S; Kuma, K; Ohsawa, N; Sakata, S; Shimizu, N; Takamatsu, J; Tanaka, K; Ueda, S; Yamaji, T, 1996) |
| "Thyroid hormone resistance syndrome is characterized by a reduced target tissue response to the action of thyroid hormone, which leads to high levels of free thyroxine and free triiodothyronine with non-suppressed levels of thyrotropin (TSH)." | 1.39 | Differentiated thyroid carcinoma in a girl with resistance to thyroid hormone management with triiodothyroacetic acid. ( Antonia Pérez-Lázaro, M; Isabel del Olmo-García, M; León-de Zayas, B; Merino-Torres, JF; Moreno-Macián, F; Navas-de Solis, S; Ramos-Prol, A, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Visser, WE | 2 |
| Ramos-Prol, A | 1 |
| Antonia Pérez-Lázaro, M | 1 |
| Isabel del Olmo-García, M | 1 |
| León-de Zayas, B | 1 |
| Moreno-Macián, F | 1 |
| Navas-de Solis, S | 1 |
| Merino-Torres, JF | 1 |
| Jiskra, J | 1 |
| Límanová, Z | 1 |
| Krude, H | 1 |
| Kühnen, P | 1 |
| Biebermann, H | 1 |
| Groeneweg, S | 1 |
| Peeters, RP | 1 |
| Visser, TJ | 1 |
| Guran, T | 1 |
| Turan, S | 1 |
| Bircan, R | 1 |
| Bereket, A | 1 |
| Anzai, R | 1 |
| Adachi, M | 1 |
| Sho, N | 1 |
| Muroya, K | 1 |
| Asakura, Y | 1 |
| Onigata, K | 1 |
| Kong, AP | 1 |
| Lam, CW | 1 |
| Chan, AO | 1 |
| Yiu, SF | 1 |
| Tiu, SC | 1 |
| Ercan, O | 1 |
| Yamada, M | 1 |
| Ueda, S | 1 |
| Takamatsu, J | 1 |
| Fukata, S | 1 |
| Tanaka, K | 1 |
| Shimizu, N | 1 |
| Sakata, S | 1 |
| Yamaji, T | 1 |
| Kuma, K | 1 |
| Ohsawa, N | 1 |
| Radetti, G | 1 |
| Persani, L | 2 |
| Molinaro, G | 1 |
| Mannavola, D | 2 |
| Cortelazzi, D | 2 |
| Chatterjee, VK | 2 |
| Beck-Peccoz, P | 3 |
| Asteria, C | 1 |
| Rajanayagam, O | 1 |
| Collingwood, TN | 1 |
| Romoli, R | 1 |
| Zamperini, P | 1 |
| Buzi, F | 1 |
| Ciralli, F | 1 |
| Ciulla, MM | 1 |
| Paliotti, R | 1 |
| Tortora, G | 1 |
| Barelli, MV | 1 |
| Buonamici, V | 1 |
| Magrini, F | 1 |
6 reviews available for 3,3',5-triiodothyroacetic acid and Generalized Resistance to Thyroid Hormone
| Article | Year |
|---|---|
Therapeutic applications of thyroid hormone analogues.
Topics: Animals; Humans; Monocarboxylic Acid Transporters; Mutation; Symporters; Thyroid Diseases; Thyroid H | 2021 |
Treatment of congenital thyroid dysfunction: Achievements and challenges.
Topics: Congenital Hypothyroidism; Hormone Replacement Therapy; Humans; Hydrolases; Infant, Newborn; Iodide | 2015 |
Therapeutic applications of thyroid hormone analogues in resistance to thyroid hormone (RTH) syndromes.
Topics: Biomimetic Materials; Female; Humans; Male; Monocarboxylic Acid Transporters; Mutation; Signal Trans | 2017 |
Long-term 3,5,3'-triiodothyroacetic acid therapy in a child with hyperthyroidism caused by thyroid hormone resistance: pharmacological study and therapeutic recommendations.
Topics: Adolescent; Adult; Atrial Premature Complexes; Attention Deficit Disorder with Hyperactivity; Child; | 2012 |
Thyroid Hormone Resistance in children.
Topics: Biomarkers; Child; Dextrothyroxine; Humans; Mutation; Risk Factors; Thyroid Hormone Receptors beta; | 2003 |
[Resistance to thyroid hormone].
Topics: Biomarkers; Diagnosis, Differential; Humans; Mutation; Thyroid Hormone Receptors beta; Thyroid Hormo | 2006 |
8 other studies available for 3,3',5-triiodothyroacetic acid and Generalized Resistance to Thyroid Hormone
| Article | Year |
|---|---|
Differentiated thyroid carcinoma in a girl with resistance to thyroid hormone management with triiodothyroacetic acid.
Topics: Carcinoma; Carcinoma, Papillary; Cell Differentiation; Child; Female; Humans; Thyroid Cancer, Papill | 2013 |
[Resistance to thyroid hormones].
Topics: Arrhythmias, Cardiac; Humans; Mutation; Thyroid Hormone Receptors beta; Thyroid Hormone Resistance S | 2014 |
9 years follow-up of a patient with pituitary form of resistance to thyroid hormones (PRTH): comparison of two treatment periods of D-thyroxine and triiodothyroacetic acid (TRIAC).
Topics: Alkaline Phosphatase; Child; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Prenatal | 2009 |
Resistance to thyroid hormone in a Chinese family with R429Q mutation in the thyroid hormone receptor beta gene.
Topics: Adult; Humans; Male; Mutation; Receptors, Thyroid Hormone; Thyroid Hormone Receptors beta; Thyroid H | 2005 |
Differences in response of thyrotropin to 3,5,3'-triiodothyronine and 3,5,3'-triiodothyroacetic acid in patients with resistance to thyroid hormone.
Topics: Adenoma; Adolescent; Child, Preschool; Female; Ferritins; Glycoprotein Hormones, alpha Subunit; Huma | 1996 |
Clinical and hormonal outcome after two years of triiodothyroacetic acid treatment in a child with thyroid hormone resistance.
Topics: Biomarkers; Child, Preschool; Female; Follow-Up Studies; Humans; Male; Pituitary Gland; Point Mutati | 1997 |
Prenatal diagnosis of thyroid hormone resistance.
Topics: Adult; DNA; Female; Fetal Blood; Fetal Diseases; Gestational Age; Heterozygote; Humans; Mutation; Pr | 1999 |
Effects of thyroid hormones on cardiac structure: a tissue characterization study in patients with thyroid disorders before and after treatment.
Topics: Adult; Antithyroid Agents; Collagen; Echocardiography; Electrocardiography; Female; Humans; Hyperthy | 2001 |