Compounds > 3'-azido-3'-deoxythymidine 5'phosphate
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3'-azido-3'-deoxythymidine 5'phosphate and HIV Infections

3'-azido-3'-deoxythymidine 5'phosphate has been researched along with HIV Infections in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (53.85)18.2507
2000's5 (38.46)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bodem, J; Buchholz, B; Corona, A; Di Santo, R; Jordan, M; Maccioni, E; Schneider, A; Spöring, I; Tramontano, E; Wöhrl, BM1
Aubertin, AM; Boggetto, N; Condom, R; Di Giorgio, A; Liotard, JF; Mehiri, M; Patino, N; Reboud-Ravaux, M1
Bénech, H; Dehée, A; Dollfus, C; Durand-Gasselin, L; Garbarg-Chenon, A; Grassi, J; Leverger, G; Pruvost, A; Tabone, MD; Vaudre, G1
Back, D; Barry, M; Beeching, N; Breckenridge, A; Carey, P; Fox, R; Nye, F; Timmins, D; Veal, G; Wild, M1
Hall, ET; Kuchta, RD; Melançon, P; Yan, JP1
Bardeguez, AD; Blanchard, S; Flynn, PM; Fridland, A; Jimenez, E; Robbins, B; Rodman, JH; Rodriguez, JF1
Back, DJ; Gibbons, SE; Hoggard, PG; Karbwang, J; Khoo, SH; Na Bangchang, K; Phiboonbhanakit, D; Wattanagoon, Y1
Back, DJ; Barry, MG; Dann, L; Gibbons, SE; Hoggard, PG; Khoo, SH; Lloyd, J; Loveday, C; Wilkins, EG1
Johnson, S1
Baker, RC; Brady, MT; Hunkler, JA; McOwen, NM; Nahata, MC; Sobol, BJ; Wintermeyer, SM1
Hamzeh, FM; Kornhauser, DM; Kuwahara, SK; Lewis, LD; Lietman, PS; Slusher, JT1
Britton, S; Eriksson, S; Jacobsson, B; Törnevik, Y1
de Clercq, E; Jansen, RW; Meijer, DK; Molema, G; Pauwels, R1

Trials

2 trial(s) available for 3'-azido-3'-deoxythymidine 5'phosphate and HIV Infections

ArticleYear
Zidovudine phosphorylation in HIV-infected patients and seronegative volunteers.
    AIDS (London, England), 1994, Volume: 8, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Adult; Biotransformation; Dideoxynucleotides; HIV Infections; HIV Seronegativity; Humans; Leukocytes, Mononuclear; Middle Aged; Phosphorylation; Reference Values; Thymine Nucleotides; Zidovudine

1994
Pharmacokinetics of zidovudine phosphorylation in human immunodeficiency virus-positive thai patients and healthy volunteers.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:7

    Topics: Adult; Anti-HIV Agents; Dideoxynucleotides; Female; HIV Infections; Humans; Male; Phosphorylation; Reverse Transcriptase Inhibitors; Thailand; Thymine Nucleotides; Zidovudine

2000

Other Studies

11 other study(ies) available for 3'-azido-3'-deoxythymidine 5'phosphate and HIV Infections

ArticleYear
Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors.
    Nucleic acids research, 2016, Mar-18, Volume: 44, Issue:5

    Topics: Amino Acid Sequence; Amino Acid Substitution; Anti-HIV Agents; Cloning, Molecular; Dideoxynucleotides; Drug Resistance, Multiple, Viral; Enzyme Inhibitors; Escherichia coli; Gene Expression; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Recombinant Proteins; Ribonuclease H, Human Immunodeficiency Virus; Thymine Nucleotides; Zidovudine

2016
AZT and AZT-monophosphate prodrugs incorporating HIV-protease substrate fragment: synthesis and evaluation as specific drug delivery systems.
    Antiviral chemistry & chemotherapy, 2006, Volume: 17, Issue:4

    Topics: Amides; Anti-HIV Agents; Cells, Cultured; Dideoxynucleotides; Drug Delivery Systems; Drug Evaluation; Drug Stability; Esters; HIV Infections; HIV Protease; HIV-1; Humans; Inhibitory Concentration 50; Models, Biological; Phosphoric Acids; Prodrugs; Protease Inhibitors; Thymidine Kinase; Thymine Nucleotides; Zidovudine

2006
High levels of zidovudine (AZT) and its intracellular phosphate metabolites in AZT- and AZT-lamivudine-treated newborns of human immunodeficiency virus-infected mothers.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Anti-HIV Agents; Dideoxynucleotides; Female; Follow-Up Studies; HIV Infections; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Leukocytes, Mononuclear; Male; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Thymine Nucleotides; Zidovudine

2008
3'-Azido-3'-deoxythymidine potently inhibits protein glycosylation. A novel mechanism for AZT cytotoxicity.
    The Journal of biological chemistry, 1994, May-20, Volume: 269, Issue:20

    Topics: Animals; CHO Cells; Cricetinae; Cytidine Monophosphate N-Acetylneuraminic Acid; Dideoxynucleotides; Glycosylation; Golgi Apparatus; HIV; HIV Infections; Humans; Intracellular Membranes; Kinetics; Membrane Proteins; Nucleoside Diphosphate Sugars; Protein Processing, Post-Translational; Thymine Nucleotides; Uridine Diphosphate Galactose; Uridine Diphosphate N-Acetylglucosamine; Zidovudine

1994
Systemic pharmacokinetics and cellular pharmacology of zidovudine in human immunodeficiency virus type 1-infected women and newborn infants.
    The Journal of infectious diseases, 1999, Volume: 180, Issue:6

    Topics: Adolescent; Adult; Anti-HIV Agents; Dideoxynucleotides; Female; Fetal Blood; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Phosphorylation; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine

1999
Zidovudine phosphorylation determined sequentially over 12 months in human immunodeficiency virus-infected patients with or without previous exposure to antiretroviral agents.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:3

    Topics: Adult; Anti-HIV Agents; Dideoxynucleotides; Female; HIV; HIV Infections; Humans; Longitudinal Studies; Male; Middle Aged; Phosphorylation; Thymine Nucleotides; Zidovudine

2001
Low-dose, sublingual AZT-monophosphate therapy for HIV+ patients?
    Medical hypotheses, 2001, Volume: 56, Issue:3

    Topics: Administration, Sublingual; Anti-HIV Agents; Dideoxynucleotides; HIV; HIV Infections; HIV Seropositivity; Humans; Models, Biological; Thymidine Kinase; Thymine Nucleotides; Virus Replication; Zidovudine

2001
Phosphorylated zidovudine concentrations in mononuclear cells in pediatric patients with human immunodeficiency virus infections.
    Pediatric AIDS and HIV infection, 1997, Volume: 8, Issue:2

    Topics: Adolescent; Anti-HIV Agents; Biological Availability; Child; Child, Preschool; Dideoxynucleotides; Dose-Response Relationship, Drug; Female; HIV Infections; Humans; Male; Monocytes; Phosphorylation; Thymine Nucleotides; Treatment Outcome; Zidovudine

1997
Intracellular zidovudine (ZDV) and ZDV phosphates as measured by a validated combined high-pressure liquid chromatography-radioimmunoassay procedure.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11

    Topics: Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dideoxynucleotides; Drug Stability; HIV Infections; Humans; Intracellular Fluid; Leukocytes, Mononuclear; Phosphorylation; Radioimmunoassay; Reproducibility of Results; Sensitivity and Specificity; Thymine Nucleotides; Tritium; Zidovudine

1992
Intracellular metabolism of 3'-azidothymidine in isolated human peripheral blood mononuclear cells.
    AIDS research and human retroviruses, 1991, Volume: 7, Issue:9

    Topics: Adult; Dideoxynucleotides; Female; Half-Life; HIV Infections; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Male; Middle Aged; Phosphorylation; Phytohemagglutinins; Thymine Nucleotides; Zidovudine

1991
Targeting of antiviral drugs to T4-lymphocytes. Anti-HIV activity of neoglycoprotein-AZTMP conjugates in vitro.
    Biochemical pharmacology, 1990, Dec-15, Volume: 40, Issue:12

    Topics: Antiviral Agents; CD4-Positive T-Lymphocytes; Dideoxynucleotides; Drug Carriers; Glycoproteins; HIV Infections; Humans; In Vitro Techniques; Lysine; Serum Albumin; Thymine Nucleotides; Zidovudine

1990