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3'-azido-2',3'-dideoxyuridine and HIV

3'-azido-2',3'-dideoxyuridine has been researched along with HIV in 10 studies

*HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2. [MeSH]

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's5 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Augustyns, K; Balzarini, J; Blaton, N; De Clercq, E; De Ranter, C; Everaert, D; Janssen, G; Jie, L; Peeters, O; Van Aerschot, A1
Bhadti, VS; Boudinot, FD; Chu, CK; Doshi, KJ; Etse, JT; Gallo, JM; Schinazi, RF1
Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Janssen, G; Pauwels, R; Van Aerschot, A1
Chu, CK; Guo, JY; Lin, TS; Prusoff, WH; Schinazi, RF; Xiang, JN1
Chen, MS; Gao, YS; Ghazzouli, I; Lin, TS; McLaren, C; Prusoff, WH1
Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R1
Boudinot, FD; Chu, CK; Doshi, KJ; Etse, JT; Gallo, JM1
Chu, CK; Colby, CB; Schinazi, RF; Sommadossi, JP; Williams, GJ; Zhu, Z1
Chu, CK; Eriksson, BF; Schinazi, RF1
Balzarini, J; de Clercq, E; Herdewijn, P; van Aerschot, A1

Reviews

1 review(s) available for 3'-azido-2',3'-dideoxyuridine and HIV

ArticleYear
Targeted therapy of human immunodeficiency virus-related disease.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1991, Volume: 5, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine

1991

Other Studies

9 other study(ies) available for 3'-azido-2',3'-dideoxyuridine and HIV

ArticleYear
Synthesis and anti-HIV evaluation of 2',3'-dideoxyribo-5-chloropyrimidine analogues: reduced toxicity of 5-chlorinated 2',3'-dideoxynucleosides.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:6

    Topics: Antiviral Agents; Cell Line; Dideoxynucleosides; HIV; Humans; Molecular Conformation; X-Ray Diffraction

1990
Brain targeting of anti-HIV nucleosides: synthesis and in vitro and in vivo studies of dihydropyridine derivatives of 3'-azido-2',3'-dideoxyuridine and 3'-azido-3'-deoxythymidine.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: Animals; Antiviral Agents; Brain; Chemical Phenomena; Chemistry; Dihydropyridines; Half-Life; HIV; Humans; Mice; Molecular Structure; Prodrugs; Zidovudine

1990
Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:10

    Topics: Animals; Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; HIV; Magnetic Resonance Spectroscopy; Purine Nucleosides; Pyrimidine Nucleosides; Structure-Activity Relationship; Virus Replication; Zidovudine

1988
Synthesis and antiviral activity of various 3'-azido analogues of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1, HTLV-III/LAV).
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:2

    Topics: Antiviral Agents; HIV; Humans; Pyrimidine Nucleosides; Structure-Activity Relationship

1988
Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogues of pyrimidine deoxyribonucleosides against retroviruses.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:2

    Topics: Antiviral Agents; Cell Line; HIV; Indicators and Reagents; Magnetic Resonance Spectroscopy; Moloney murine leukemia virus; Pyrimidine Nucleosides; Spectrophotometry; Structure-Activity Relationship

1987
Hybrid pharmacokinetic models to describe anti-HIV nucleoside brain disposition following parent and prodrug administration in mice.
    Pharmaceutical research, 1991, Volume: 8, Issue:2

    Topics: Animals; Antiviral Agents; Brain; Dihydropyridines; Female; HIV; Mice; Models, Biological; Nucleosides; Prodrugs; Zidovudine

1991
Cellular metabolism of 3'-azido-2',3'-dideoxyuridine with formation of 5'-O-diphosphohexose derivatives by previously unrecognized metabolic pathways for 2'-deoxyuridine analogs.
    Molecular pharmacology, 1990, Volume: 38, Issue:6

    Topics: Antiviral Agents; Bone Marrow; Chromatography, High Pressure Liquid; Dideoxynucleotides; HIV; Humans; Leukocytes, Mononuclear; Thymine Nucleotides; Zidovudine

1990
Phosphorylation of 3'-azido-2',3'-dideoxyuridine and preferential inhibition of human and simian immunodeficiency virus reverse transcriptases by its 5'-triphosphate.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:10

    Topics: Cells, Cultured; Chromatography, High Pressure Liquid; DNA Polymerase II; HIV; Humans; Kinetics; Phosphorylation; Phosphotransferases; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Thymidine Kinase; Zidovudine

1989
5-Chloro-substituted derivatives of 2', 3'-didehydro-2',3'-dideoxyuridine, 3'-fluoro-2',3'-dideoxyuridine and 3'-azido-2',3'-dideoxyuridine as anti-HIV agents.
    Biochemical pharmacology, 1989, Mar-15, Volume: 38, Issue:6

    Topics: Animals; Antiviral Agents; Cell Line; Dideoxynucleosides; HIV; Humans; Kinetics; Thymidine Kinase; Virus Replication; Zidovudine

1989