Compounds > 3--azido-2--3--dideoxycytidine

3--azido-2--3--dideoxycytidine and Body-Weight

3--azido-2--3--dideoxycytidine has been researched along with Body-Weight* in 1 studies

Other Studies

1 other study(ies) available for 3--azido-2--3--dideoxycytidine and Body-Weight

Article	Year
Synthesis and antineoplastic activity of 3'-azido and 3'-amino analogues of pyrimidine deoxyribonucleoside. Journal of medicinal chemistry, 1983, Volume: 26, Issue:4 Several new 3'-azido and 3'-amino nucleosides (8, 9, 12, and 13) have been synthesized and their biological activities evaluated. Among them, 3'-amino-2',3'-dideoxycytidine (13) was found to exhibit potent cytotoxic activity against both L1210 and S-180 cells in vitro with an ID50 of 0.7 and 4.0 microM, respectively. Furthermore, 13 has also shown antitumor activity against L1210 tumor bearing mice with a T/C X 100 value of 283. Topics: Animals; Antineoplastic Agents; Body Weight; DNA Replication; Leukemia L1210; Mice; Pyrimidine Nucleosides	1983

Article

Year

Synthesis and antineoplastic activity of 3'-azido and 3'-amino analogues of pyrimidine deoxyribonucleoside.

Journal of medicinal chemistry, 1983, Volume: 26, Issue:4

Several new 3'-azido and 3'-amino nucleosides (8, 9, 12, and 13) have been synthesized and their biological activities evaluated. Among them, 3'-amino-2',3'-dideoxycytidine (13) was found to exhibit potent cytotoxic activity against both L1210 and S-180 cells in vitro with an ID50 of 0.7 and 4.0 microM, respectively. Furthermore, 13 has also shown antitumor activity against L1210 tumor bearing mice with a T/C X 100 value of 283.

Topics: Animals; Antineoplastic Agents; Body Weight; DNA Replication; Leukemia L1210; Mice; Pyrimidine Nucleosides

1983