Page last updated: 2024-09-03

3-(n-prolylamine)-2-oxo-1-pyrrolidineacetamide and Schizophrenia

3-(n-prolylamine)-2-oxo-1-pyrrolidineacetamide has been researched along with Schizophrenia in 2 studies

*Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior. [MeSH]

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Basu, D; Johnson, RL; Kwiecien, JM; Mishra, RK; Tan, ML1
Beyaert, MG; Daya, RP; Dyck, BA; Johnson, RL; Mishra, RK1

Other Studies

2 other study(ies) available for 3-(n-prolylamine)-2-oxo-1-pyrrolidineacetamide and Schizophrenia

ArticleYear
Preclinical pharmacokinetic and toxicological evaluation of MIF-1 peptidomimetic, PAOPA: examining the pharmacology of a selective dopamine D2 receptor allosteric modulator for the treatment of schizophrenia.
    Peptides, 2013, Volume: 42

    Topics: Administration, Intravenous; Administration, Oral; Animals; Antipsychotic Agents; Brain; Drug Evaluation, Preclinical; Humans; Male; Molecular Targeted Therapy; MSH Release-Inhibiting Hormone; Peptidomimetics; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Schizophrenia; Tissue Distribution

2013
PAOPA, a potent dopamine D2 receptor allosteric modulator, prevents and reverses behavioral and biochemical abnormalities in an amphetamine-sensitized preclinical animal model of schizophrenia.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2013, Volume: 23, Issue:3

    Topics: Allosteric Regulation; Amphetamine; Animals; Behavior, Animal; Brain; Disease Models, Animal; Dopamine; Male; Motor Activity; Neostriatum; Nucleus Accumbens; Prefrontal Cortex; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Schizophrenia

2013