3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid and Malaria

3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid has been researched along with Malaria in 10 studies

*Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia. [MeSH]

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (20.00)	18.2507
2000's	4 (40.00)	29.6817
2010's	4 (40.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Devreux, V; Jomaa, H; Van Calenbergh, S; Van der Eycken, J; Wiesner, J	1
Cos, P; Maes, L; Van Calenbergh, S; Verbrugghen, T	1
Bacher, A; Behrendt, C; Brücher, K; Fischer, M; Gräwert, T; Held, J; Illarionov, B; Konzuch, S; Kurz, T; Lienau, C; Maes, L; Mordmüller, B; Wittlin, S	1
Calderón, F; Fernández-Álvaro, E; Hong, WD; Nixon, GL; O'Neill, PM	1
DeSieno, MA; Griffin, BM; Johannes, TW; Kelleher, NL; Metcalf, WW; Thomas, PM; Zhao, H	1
Beck, E; Henschker, D; Jomaa, H; Ortmann, R; Reichenberg, A; Schlitzer, M; Wiesner, J	2
Altincicek, B; Beck, E; Eberl, M; Hintz, M; Jomaa, H; Lichtenthaler, HK; Sanderbrand, S; Soldati, D; Türbachova, I; Weidemeyer, C; Wiesner, J; Zeidler, J	1
Ridley, RG	1
Altincicek, B; Beck, E; Dreiseidler, E; Jomaa, H; Reichenberg, A; Sanderbrand, S; Schlitzer, M; Weidemeyer, C; Wiesner, J	1

Reviews

1 review(s) available for 3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid and Malaria

Article	Year
Antimalarial Chemotherapy: Natural Product Inspired Development of Preclinical and Clinical Candidates with Diverse Mechanisms of Action. Journal of medicinal chemistry, 2016, 06-23, Volume: 59, Issue:12 Topics: Antimalarials; Biological Products; Chemistry, Pharmaceutical; Humans; Malaria; Molecular Structure	2016

Other Studies

9 other study(ies) available for 3-(n-acetyl-n-hydroxy)aminopropylphosphonic acid and Malaria

Article	Year
Synthesis and evaluation of alpha,beta-unsaturated alpha-aryl-substituted fosmidomycin analogues as DXR inhibitors. Bioorganic & medicinal chemistry letters, 2007, Sep-01, Volume: 17, Issue:17 Topics: Aldose-Ketose Isomerases; Animals; Antimalarials; Chemistry, Pharmaceutical; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fosfomycin; Inhibitory Concentration 50; Malaria; Models, Chemical; Molecular Structure; Multienzyme Complexes; Oxidoreductases; Plasmodium falciparum; Structure-Activity Relationship	2007
Synthesis and evaluation of alpha-halogenated analogues of 3-(acetylhydroxyamino)propylphosphonic acid (FR900098) as antimalarials. Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14 Topics: Acute Disease; Animals; Antimalarials; Fosfomycin; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum; Structure-Activity Relationship	2010
Prodrugs of reverse fosmidomycin analogues. Journal of medicinal chemistry, 2015, Feb-26, Volume: 58, Issue:4 Topics: Animals; Antimalarials; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Fosfomycin; HeLa Cells; Humans; Malaria; Mice; Mice, SCID; Molecular Structure; Plasmodium berghei; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship	2015
Deciphering the late biosynthetic steps of antimalarial compound FR-900098. Chemistry & biology, 2010, Jan-29, Volume: 17, Issue:1 Topics: Antimalarials; Biosynthetic Pathways; Escherichia coli; Escherichia coli Proteins; Fosfomycin; Genes, Bacterial; Humans; Malaria	2010
Acyloxyalkyl ester prodrugs of FR900098 with improved in vivo anti-malarial activity. Bioorganic & medicinal chemistry letters, 2003, Jul-07, Volume: 13, Issue:13 Topics: Animals; Antimalarials; Biological Availability; Fosfomycin; Indicators and Reagents; Lysophospholipids; Malaria; Mevalonic Acid; Mice; Mice, Inbred BALB C; Prodrugs	2003
Alkoxycarbonyloxyethyl ester prodrugs of FR900098 with improved in vivo antimalarial activity. Archiv der Pharmazie, 2005, Volume: 338, Issue:7 Topics: Administration, Oral; Aldose-Ketose Isomerases; Animals; Antimalarials; Biological Availability; Dose-Response Relationship, Drug; Fosfomycin; Malaria; Mice; Mice, Inbred BALB C; Multienzyme Complexes; Oxidoreductases; Plasmodium; Prodrugs; Quantitative Structure-Activity Relationship	2005
Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs. Science (New York, N.Y.), 1999, Sep-03, Volume: 285, Issue:5433 Topics: Aldose-Ketose Isomerases; Amino Acid Sequence; Animals; Antimalarials; Cloning, Molecular; Enzyme Inhibitors; Fosfomycin; Genes, Protozoan; Hemiterpenes; Malaria; Malaria, Falciparum; Mevalonic Acid; Mice; Molecular Sequence Data; Multienzyme Complexes; Organelles; Organophosphorus Compounds; Oxidoreductases; Pentosephosphates; Plasmodium falciparum; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Terpenes	1999
Planting the seeds of new antimalarial drugs. Science (New York, N.Y.), 1999, Sep-03, Volume: 285, Issue:5433 Topics: Aldose-Ketose Isomerases; Animals; Antimalarials; Drug Design; Enzyme Inhibitors; Fosfomycin; Hemiterpenes; Humans; Malaria; Malaria, Falciparum; Mice; Multienzyme Complexes; Organelles; Organophosphorus Compounds; Oxidoreductases; Plasmodium falciparum; Steroids; Transferases	1999
Diaryl ester prodrugs of FR900098 with improved in vivo antimalarial activity. Bioorganic & medicinal chemistry letters, 2001, Mar-26, Volume: 11, Issue:6 Topics: Aldose-Ketose Isomerases; Animals; Antimalarials; Disease Models, Animal; Fosfomycin; Malaria; Mice; Multienzyme Complexes; Organophosphonates; Oxidoreductases; Plasmodium; Prodrugs; Treatment Outcome	2001