3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Thrombosis in 2 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a model of fatal pulmonary thromboembolism induced by intravenous injection of ADP (300 micrograms/g), YC-1 was effective in reducing mortality when administered intraperitoneally at doses of 10-30 micrograms/g." | 1.30 | YC-1, a nitric oxide-independent activator of soluble guanylate cyclase, inhibits platelet-rich thrombosis in mice. ( Ko, FN; Kuo, SC; Lee, FY; Teng, CM; Wu, CC, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cwiklicki, A | 1 |
| Rehse, K | 1 |
| Teng, CM | 1 |
| Wu, CC | 1 |
| Ko, FN | 1 |
| Lee, FY | 1 |
| Kuo, SC | 1 |
2 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Thrombosis
| Article | Year |
|---|---|
Antiaggregating and antithrombotic activities of new 1, 2, 3-triazolecarboxamides.
Topics: Animals; Fibrinolytic Agents; Guanylate Cyclase; Indazoles; Lasers; Phosphoric Diester Hydrolases; P | 2004 |
YC-1, a nitric oxide-independent activator of soluble guanylate cyclase, inhibits platelet-rich thrombosis in mice.
Topics: Adenosine Diphosphate; Animals; Bleeding Time; Blood Coagulation; Blood Platelets; Disease Models, A | 1997 |