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3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Retinal Diseases

3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Retinal Diseases in 3 studies

3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.

Retinal Diseases: Diseases involving the RETINA.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DeNiro, M3
Al-Halafi, A1
Al-Mohanna, FH2
Alsmadi, O1
Al-Mohanna, FA3

Other Studies

3 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Retinal Diseases

ArticleYear
Pleiotropic effects of YC-1 selectively inhibit pathological retinal neovascularization and promote physiological revascularization in a mouse model of oxygen-induced retinopathy.
    Molecular pharmacology, 2010, Volume: 77, Issue:3

    Topics: Animals; Animals, Newborn; Disease Models, Animal; Indazoles; Mice; Mice, Inbred C57BL; Neovasculari

2010
Inhibition of reactive gliosis prevents neovascular growth in the mouse model of oxygen-induced retinopathy.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Animals; Blotting, Western; Cell Line; Cell Movement; Cell Proliferation; Cells, Cultured; Fluoresce

2011
Zinc transporter 8 (ZnT8) expression is reduced by ischemic insults: a potential therapeutic target to prevent ischemic retinopathy.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Animals; Cation Transport Proteins; Cell Line; Enzyme Activators; Gene Expression Regulation; Hypoxi

2012