3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Reperfusion Injury in 6 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our findings indicate that 20%EN is the minimally effective dosage of EN which promotes the recovery of intestinal barrier function after IRI in a rat model." | 1.43 | Partial Enteral Nutrition Mitigated Ischemia/Reperfusion-Induced Damage of Rat Small Intestinal Barrier. ( Gao, X; Jiang, T; Li, C; Li, J; Li, N; Tian, F; Wang, X; Wu, C; Zhang, L, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hong, YA | 1 |
| Jung, SY | 1 |
| Yang, KJ | 1 |
| Im, DS | 1 |
| Jeong, KH | 1 |
| Park, CW | 1 |
| Hwang, HS | 1 |
| Dong, W | 1 |
| Yu, P | 1 |
| Zhang, T | 1 |
| Zhu, C | 1 |
| Qi, J | 1 |
| Liang, J | 1 |
| Lee, WT | 1 |
| Tai, SH | 1 |
| Lin, YW | 1 |
| Wu, TS | 1 |
| Lee, EJ | 1 |
| Wu, C | 1 |
| Wang, X | 1 |
| Jiang, T | 1 |
| Li, C | 1 |
| Zhang, L | 1 |
| Gao, X | 1 |
| Tian, F | 1 |
| Li, N | 1 |
| Li, J | 1 |
| Hsieh, YH | 1 |
| Huang, SS | 1 |
| Day, YJ | 1 |
| Wei, FC | 1 |
| Hung, LM | 1 |
| Yeh, WL | 1 |
| Lu, DY | 1 |
| Lin, CJ | 1 |
| Liou, HC | 1 |
| Fu, WM | 1 |
6 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Reperfusion Injury
| Article | Year |
|---|---|
Cilastatin Preconditioning Attenuates Renal Ischemia-Reperfusion Injury via Hypoxia Inducible Factor-1α Activation.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Cilastatin; Humans; Hypoxia-Inducible Factor 1, alpha | 2020 |
Adrenomedullin serves a role in the humoral pathway of delayed remote ischemic preconditioning via a hypoxia-inducible factor-1α-associated mechanism.
Topics: Adrenomedullin; Animals; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Hypoxia-Inducible | 2018 |
YC‑1 reduces inflammatory responses by inhibiting nuclear factor‑κB translocation in mice subjected to transient focal cerebral ischemia.
Topics: Animals; Brain Edema; Brain Ischemia; Indazoles; Interleukin-1beta; Interleukin-6; Matrix Metallopro | 2018 |
Partial Enteral Nutrition Mitigated Ischemia/Reperfusion-Induced Damage of Rat Small Intestinal Barrier.
Topics: Animals; Antioxidants; Enteral Nutrition; Enzyme Activators; Hypoxia-Inducible Factor 1, alpha Subun | 2016 |
Involvement of YC-1 in extracellular signal-regulated kinase action in rat cremasteric muscle.
Topics: Animals; Capillaries; Extracellular Signal-Regulated MAP Kinases; Guanylate Cyclase; Indazoles; Leuk | 2010 |
Inhibition of hypoxia-induced increase of blood-brain barrier permeability by YC-1 through the antagonism of HIF-1alpha accumulation and VEGF expression.
Topics: Animals; Blood-Brain Barrier; Cell Hypoxia; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protei | 2007 |