3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Renal Insufficiency in 1 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nayak, BK | 1 |
| Shanmugasundaram, K | 1 |
| Friedrichs, WE | 1 |
| Cavaglierii, RC | 1 |
| Patel, M | 1 |
| Barnes, J | 1 |
| Block, K | 1 |
1 other study available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Renal Insufficiency
| Article | Year |
|---|---|
HIF-1 Mediates Renal Fibrosis in OVE26 Type 1 Diabetic Mice.
Topics: Animals; Antioxidants; Cell Line; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Extracellular M | 2016 |