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3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Osteosarcoma

3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Osteosarcoma in 2 studies

3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.

Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
He, G1
Pan, X1
Liu, X2
Zhu, Y1
Ma, Y1
Du, C1
Mao, C1
Liang, D1
Yang, M1
Guo, B1
Yang, L1
Cao, J1
Zhang, X1

Other Studies

2 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Osteosarcoma

ArticleYear
HIF-1α-Mediated Mitophagy Determines ZnO Nanoparticle-Induced Human Osteosarcoma Cell Death both In Vitro and In Vivo.
    ACS applied materials & interfaces, 2020, Oct-28, Volume: 12, Issue:43

    Topics: Antineoplastic Agents; Bone Neoplasms; Cell Death; Cell Proliferation; Drug Screening Assays, Antitu

2020
HIF-1α induced by β-elemene protects human osteosarcoma cells from undergoing apoptosis.
    Journal of cancer research and clinical oncology, 2012, Volume: 138, Issue:11

    Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Dose-R

2012