3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Invasiveness, Neoplasm in 5 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The molecular mechanisms of ovarian cancer cell invasion under hypoxia remain unclear." | 1.42 | Hypoxia promotes HO-8910PM ovarian cancer cell invasion via Snail-mediated MT1-MMP upregulation. ( Deng, LL; Lin, P; Liu, Y; Lu, C; Qin, Z; Sun, L, 2015) |
| "In contrast, prostate cancer cells exposed to acute hypoxia (≤6 h) displayed increased motility, clonogenic survival, and invasive capacity." | 1.37 | Impact of hypoxia on the metastatic potential of human prostate cancer cells. ( Bae, K; Dai, Y; Siemann, DW, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, L | 1 |
| Lin, P | 1 |
| Qin, Z | 1 |
| Liu, Y | 1 |
| Deng, LL | 1 |
| Lu, C | 1 |
| Hong, B | 1 |
| Lui, VW | 1 |
| Hui, EP | 1 |
| Lu, Y | 1 |
| Leung, HS | 1 |
| Wong, EY | 1 |
| Cheng, SH | 1 |
| Ng, MH | 1 |
| Mills, GB | 1 |
| Chan, AT | 1 |
| Wang, L | 1 |
| Zhou, W | 1 |
| Gou, S | 1 |
| Wang, T | 1 |
| Liu, T | 1 |
| Wang, C | 1 |
| Dai, Y | 1 |
| Bae, K | 1 |
| Siemann, DW | 1 |
| Shin, DH | 1 |
| Kim, JH | 1 |
| Jung, YJ | 1 |
| Kim, KE | 1 |
| Jeong, JM | 1 |
| Chun, YS | 1 |
| Park, JW | 1 |
5 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Hypoxia promotes HO-8910PM ovarian cancer cell invasion via Snail-mediated MT1-MMP upregulation.
Topics: Animals; Cell Culture Techniques; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Chick Embryo; | 2015 |
Reverse phase protein array identifies novel anti-invasion mechanisms of YC-1.
Topics: Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; Checkpo | 2010 |
Insulin promotes proliferative vitality and invasive capability of pancreatic cancer cells via hypoxia-inducible factor 1alpha pathway.
Topics: Cell Line, Tumor; Cell Proliferation; Guanylate Cyclase; Humans; Hypoxia-Inducible Factor 1, alpha S | 2010 |
Impact of hypoxia on the metastatic potential of human prostate cancer cells.
Topics: Cell Death; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Enzyme | 2011 |
Preclinical evaluation of YC-1, a HIF inhibitor, for the prevention of tumor spreading.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Collagen; Drug Combinations; Drug S | 2007 |