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3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Inflammation

3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Inflammation in 5 studies

3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Yan, Z1
An, J1
Shang, Q1
Zhou, N1
Ma, J1
Cho, JL1
Allanson, M1
Reeve, VE1
Zampell, JC1
Yan, A1
Avraham, T1
Daluvoy, S1
Weitman, ES1
Mehrara, BJ1
Subbaramaiah, K1
Yoshimatsu, K1
Scherl, E1
Das, KM1
Glazier, KD1
Golijanin, D1
Soslow, RA1
Tanabe, T1
Naraba, H1
Dannenberg, AJ1

Other Studies

5 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
YC-1 Inhibits VEGF and Inflammatory Mediators Expression on Experimental Central Retinal Vein Occlusion in Rhesus Monkey.
    Current eye research, 2018, Volume: 43, Issue:4

    Topics: Animals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Follow-Up Studies; Guanylate Cyc

2018
Hypoxia inducible factor-1α contributes to UV radiation-induced inflammation, epidermal hyperplasia and immunosuppression in mice.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2012, Volume: 11, Issue:2

    Topics: Animals; Dermatitis, Contact; Edema; Female; Gene Expression Regulation; Hyperplasia; Hypoxia-Induci

2012
HIF-1α coordinates lymphangiogenesis during wound healing and in response to inflammation.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2012, Volume: 26, Issue:3

    Topics: Animals; Blotting, Western; CD4 Antigens; Cell Hypoxia; Edema; Female; Gene Expression; Hypoxia; Hyp

2012
Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1.
    The Journal of biological chemistry, 2004, Mar-26, Volume: 279, Issue:13

    Topics: Blotting, Northern; Blotting, Western; Cell Line, Tumor; Cells, Cultured; Colon; DNA-Binding Protein

2004