3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Hypertension, Pulmonary in 2 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, L | 1 |
| Zhang, W | 1 |
| Lin, F | 1 |
| Lu, X | 1 |
| Chen, W | 1 |
| Li, X | 1 |
| Zhou, X | 1 |
| Su, R | 1 |
| Wang, L | 1 |
| Zheng, Z | 1 |
| Li, S | 1 |
| Huh, JW | 1 |
| Kim, SY | 1 |
| Lee, JH | 1 |
| Lee, YS | 1 |
2 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Hypertension, Pulmonary
| Article | Year |
|---|---|
Synthesis and biological evaluation of pyrazolo[3,4-b]pyridine-3-yl pyrimidine derivatives as sGC stimulators for the treatment of pulmonary hypertension.
Topics: Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Male; M | 2019 |
YC-1 attenuates hypoxia-induced pulmonary arterial hypertension in mice.
Topics: Animals; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Endothelin-1; E | 2011 |