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3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Glioma

3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Glioma in 1 studies

3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xu, Y1
Gu, Y1
Keep, RF1
Heth, J1
Muraszko, KM1
Xi, G1
Hua, Y1

Other Studies

1 other study available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Glioma

ArticleYear
Thrombin up-regulates vascular endothelial growth factor in experimental gliomas.
    Neurological research, 2009, Volume: 31, Issue:7

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Disease Models, Animal; Enzyme Inhibitors; Glioma; Hemos

2009