3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Experimental Mammary Neoplasms in 2 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In YC-1-treated breast cancer cells and tumour specimens from YC-1-treated MDA-MB-468 xenografts, EZH2 expression was analysed by Western blotting." | 1.40 | YC-1 inhibits proliferation of breast cancer cells by down-regulating EZH2 expression via activation of c-Cbl and ERK. ( Chang, LC; Chou, RH; Hsieh, MT; Huang, LJ; Hung, HY; Kuo, SC; Lee, FY; Lin, HY; Teng, CM; Tsai, MT; Yu, YL, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, LC | 1 |
| Lin, HY | 1 |
| Tsai, MT | 1 |
| Chou, RH | 1 |
| Lee, FY | 1 |
| Teng, CM | 1 |
| Hsieh, MT | 1 |
| Hung, HY | 1 |
| Huang, LJ | 1 |
| Yu, YL | 1 |
| Kuo, SC | 1 |
| Harrison, H | 1 |
| Rogerson, L | 1 |
| Gregson, HJ | 1 |
| Brennan, KR | 1 |
| Clarke, RB | 1 |
| Landberg, G | 1 |
2 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
YC-1 inhibits proliferation of breast cancer cells by down-regulating EZH2 expression via activation of c-Cbl and ERK.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Cell Survival; Dose-Response R | 2014 |
Contrasting hypoxic effects on breast cancer stem cell hierarchy is dependent on ER-α status.
Topics: Animals; Blotting, Western; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Estrogen Antagonists; | 2013 |