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3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Edema, Pulmonary

3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Edema, Pulmonary in 1 studies

3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.

Research Excerpts

ExcerptRelevanceReference
"Acute lung injury was associated with a higher degree of pulmonary HIF-1α and iNOS expression as well as apoptosis in the lungs."1.38Inhibition of hypoxia inducible factor-1α ameliorates lung injury induced by trauma and hemorrhagic shock in rats. ( Hu, R; Huang, Y; Jiang, H; Li, QF; Xu, H, 2012)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jiang, H1
Huang, Y1
Xu, H1
Hu, R1
Li, QF1

Other Studies

1 other study available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Edema, Pulmonary

ArticleYear
Inhibition of hypoxia inducible factor-1α ameliorates lung injury induced by trauma and hemorrhagic shock in rats.
    Acta pharmacologica Sinica, 2012, Volume: 33, Issue:5

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Caspase 3; Cytoprotection; Disease Models, Animal;

2012