3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Cirrhosis in 3 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In vitro fibrosis was blocked by Ki16425 and was further amplified by oleoyl-LPA." | 2.79 | Pro-fibrotic activity of lysophosphatidic acid in adipose tissue: in vivo and in vitro evidence. ( Bascands, JL; Bouloumié, A; Decaunes, P; Gres, S; Langin, D; Rancoule, C; Saulnier-Blache, JS; Valet, P; Viaud, M; Viguerie, N, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rancoule, C | 1 |
| Viaud, M | 1 |
| Gres, S | 1 |
| Viguerie, N | 1 |
| Decaunes, P | 1 |
| Bouloumié, A | 1 |
| Langin, D | 1 |
| Bascands, JL | 1 |
| Valet, P | 1 |
| Saulnier-Blache, JS | 1 |
| Nayak, BK | 1 |
| Shanmugasundaram, K | 1 |
| Friedrichs, WE | 1 |
| Cavaglierii, RC | 1 |
| Patel, M | 1 |
| Barnes, J | 1 |
| Block, K | 1 |
| Kimura, K | 1 |
| Iwano, M | 1 |
| Higgins, DF | 1 |
| Yamaguchi, Y | 1 |
| Nakatani, K | 1 |
| Harada, K | 1 |
| Kubo, A | 1 |
| Akai, Y | 1 |
| Rankin, EB | 1 |
| Neilson, EG | 1 |
| Haase, VH | 1 |
| Saito, Y | 1 |
1 trial available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Cirrhosis
| Article | Year |
|---|---|
Pro-fibrotic activity of lysophosphatidic acid in adipose tissue: in vivo and in vitro evidence.
Topics: Actins; Adipose Tissue; Animals; Collagen; Enzyme Activators; Female; Fibrosis; Humans; Hypoxia-Indu | 2014 |
2 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Cirrhosis
| Article | Year |
|---|---|
HIF-1 Mediates Renal Fibrosis in OVE26 Type 1 Diabetic Mice.
Topics: Animals; Antioxidants; Cell Line; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Extracellular M | 2016 |
Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis.
Topics: Aging; Animals; Disease Models, Animal; Enzyme Activators; Epithelial Cells; Female; Fibrosis; Gene | 2008 |