3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Chronic Lung Injury in 2 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute lung injury was associated with a higher degree of pulmonary HIF-1α and iNOS expression as well as apoptosis in the lungs." | 1.38 | Inhibition of hypoxia inducible factor-1α ameliorates lung injury induced by trauma and hemorrhagic shock in rats. ( Hu, R; Huang, Y; Jiang, H; Li, QF; Xu, H, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, HD | 1 |
| Liu, YJ | 1 |
| Chen, J | 1 |
| Chen, MY | 1 |
| Ouyang, B | 1 |
| Guan, XD | 1 |
| Jiang, H | 1 |
| Huang, Y | 1 |
| Xu, H | 1 |
| Hu, R | 1 |
| Li, QF | 1 |
2 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Chronic Lung Injury
| Article | Year |
|---|---|
The pivotal role of HIF-1α in lung inflammatory injury induced by septic mesenteric lymph.
Topics: A549 Cells; Animals; Cell Survival; Cytokines; Endothelial Cells; Gene Silencing; Humans; Hypoxia-In | 2017 |
Inhibition of hypoxia inducible factor-1α ameliorates lung injury induced by trauma and hemorrhagic shock in rats.
Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Caspase 3; Cytoprotection; Disease Models, Animal; | 2012 |