3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole has been researched along with Carotid Stenosis in 2 studies
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole: antineoplastic; activates platelet guanylate cyclase; a radiosensitizing agent and guanylate cyclase activator; structure in first source
lificiguat : A member of the class of indazoles that is 1H-indazole which is substituted by a benzyl group at position 1 and a 5-(hydroxymethyl)-2-furyl group at position 3. It is an activator of soluble guanylate cyclase and inhibits platelet aggregation.
Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tulis, DA | 2 |
| Durante, W | 2 |
| Peyton, KJ | 2 |
| Chapman, GB | 1 |
| Evans, AJ | 2 |
| Schafer, AI | 2 |
| Bohl Masters, KS | 1 |
| Lipke, EA | 1 |
| Schiesser, RL | 1 |
| West, JL | 1 |
2 other studies available for 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole and Carotid Stenosis
| Article | Year |
|---|---|
YC-1, a benzyl indazole derivative, stimulates vascular cGMP and inhibits neointima formation.
Topics: Angioplasty, Balloon; Animals; Carotid Arteries; Carotid Artery Injuries; Carotid Stenosis; Cyclic G | 2000 |
YC-1-mediated vascular protection through inhibition of smooth muscle cell proliferation and platelet function.
Topics: Angioplasty, Balloon; Animals; Arterial Occlusive Diseases; Blood Platelets; Carotid Stenosis; Cell | 2002 |